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In genomics, differential abundance and expression analyses are complicated by the compositional nature of sequence count data, which reflect only relative-not absolute-abundances or expression levels. Many existing methods attempt to…

Methodology · Statistics 2025-12-16 Won Gu , Francesca Chiaromonte , Justin D. Silverman

An accurate and up-to-date topology is critical for situational awareness of a power grid; however, wrong switch statuses due to physical damage, communication error, or cyber-attack, can often result in topology errors. To maintain…

Systems and Control · Electrical Eng. & Systems 2024-07-16 Shimiao Li , Amritanshu Pandey , Larry Pileggi

Calibrated uncertainty estimates in machine learning are crucial to many fields such as autonomous vehicles, medicine, and weather and climate forecasting. While there is extensive literature on uncertainty calibration for classification,…

Machine Learning · Computer Science 2021-03-16 Eric Zelikman , Christopher Healy , Sharon Zhou , Anand Avati

In the era of Model-as-a-Service, organizations increasingly rely on third-party AI models for rapid deployment. However, the dynamic nature of emerging AI applications, the continual introduction of new datasets, and the growing number of…

Machine Learning · Computer Science 2026-02-10 Zihan Zhu , Yanqiu Wu , Qiongkai Xu

Practical employment of Bayesian trial designs is still rare. Even if accepted in principle, the regulators have commonly required that such designs be calibrated according to an upper bound for the frequentist type I error rate. This…

Methodology · Statistics 2026-03-25 Elja Arjas , Dario Gasbarra

The joint prediction of continuous fields and statistical estimation of the underlying discrete parameters is a common problem for many physical systems, governed by PDEs. Hitherto, it has been separately addressed by employing operator…

Machine Learning · Computer Science 2024-11-06 Levi E. Lingsch , Dana Grund , Siddhartha Mishra , Georgios Kissas

In multiple testing scenarios, typically the sign of a parameter is inferred when its estimate exceeds some significance threshold in absolute value. Typically, the significance threshold is chosen to control the experimentwise type I error…

Methodology · Statistics 2018-01-03 Chaoyu Yu , Peter D. Hoff

Algorithmic bias is of increasing concern, both to the research community, and society at large. Bias in AI is more abstract and unintuitive than traditional forms of discrimination and can be more difficult to detect and mitigate. A clear…

Machine Learning · Computer Science 2021-10-12 Cody Blakeney , Gentry Atkinson , Nathaniel Huish , Yan Yan , Vangelis Metris , Ziliang Zong

Estimating longitudinal treatment effects is essential for sequential decision-making but is challenging due to treatment-confounder feedback. While Iterative Conditional Expectation (ICE) G-computation offers a principled approach, its…

Machine Learning · Computer Science 2026-02-16 Wenxin Chen , Weishen Pan , Kyra Gan , Fei Wang

Computer experiments have become ubiquitous in science and engineering. Commonly, runs of these simulations demand considerable time and computing, making experimental design extremely important in gaining high quality information with…

Statistics Theory · Mathematics 2017-05-15 Benjamin Haaland , Wenjia Wang , Vaibhav Maheshwari

Is it possible to detect if the sample paths of a stochastic process almost surely admit a finite expansion with respect to some/any basis? The determination is to be made on the basis of a finite collection of discretely/noisily observed…

Statistics Theory · Mathematics 2021-11-03 Neda Mohammadi , Victor M. Panaretos

Simulation can enable the study of recommender system (RS) evolution while circumventing many of the issues of empirical longitudinal studies; simulations are comparatively easier to implement, are highly controlled, and pose no ethical…

Computers and Society · Computer Science 2021-08-02 Amy A. Winecoff , Matthew Sun , Eli Lucherini , Arvind Narayanan

Continuous Software Engineering (CSE) is widely adopted in the industry, integrating practices such as Continuous Integration and Continuous Deployment (CI/CD). Beyond technical aspects, CSE also encompasses business activities like…

Software Engineering · Computer Science 2025-05-09 Anastasiia Tkalich , Eriks Klotins , Nils Brede Moe

We propose confidence regions for the parameters of incomplete models with exact coverage of the true parameter in finite samples. Our confidence region inverts a test, which generalizes Monte Carlo tests to incomplete models. The test…

Econometrics · Economics 2025-10-07 Lixiong Li , Marc Henry

Generalised Symbolic Trajectory Evaluation (GSTE) is a high-capacity formal verification technique for hardware. GSTE uses abstraction, meaning that details of the circuit behaviour are removed from the circuit model. A semantics for GSTE…

Logic in Computer Science · Computer Science 2015-07-01 Koen Claessen , Jan-Willem Roorda

Sequential decision making significantly speeds up research and is more cost-effective compared to fixed-n methods. We present a method for sequential decision making for stratified count data that retains Type-I error guarantee or false…

Methodology · Statistics 2023-02-23 Rosanne J. Turner , Peter D. Grünwald

We consider comparisons of statistical learning algorithms using multiple data sets, via leave-one-in cross-study validation: each of the algorithms is trained on one data set; the resulting model is then validated on each remaining data…

Applications · Statistics 2015-06-02 Lorenzo Trippa , Levi Waldron , Curtis Huttenhower , Giovanni Parmigiani

Sensitivity analysis for measurement error can be applied in the absence of validation data by means of regression calibration and simulation-extrapolation. These have not been compared for this purpose. A simulation study was conducted…

Applications · Statistics 2021-06-09 Linda Nab , Rolf H. H. Groenwold

Bayesian analysis is a framework for parameter estimation that applies even in uncertainty regimes where the commonly used local (frequentist) analysis based on the Cram\'er-Rao bound is not well defined. In particular, it applies when no…

Quantum Physics · Physics 2021-03-17 Simon Morelli , Ayaka Usui , Elizabeth Agudelo , Nicolai Friis

The lack of non-parametric statistical tests for confounding bias significantly hampers the development of robust, valid and generalizable predictive models in many fields of research. Here I propose the partial and full confounder tests,…

Machine Learning · Computer Science 2025-05-30 Tamas Spisak
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