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Over time, the performance of clinical prediction models may deteriorate due to changes in clinical management, data quality, disease risk and/or patient mix. Such prediction models must be updated in order to remain useful. Here, we…

In recent years, predictive maintenance (PMx) has gained prominence for its potential to enhance efficiency, automation, accuracy, and cost-effectiveness while reducing human involvement. Importantly, PMx has evolved in tandem with digital…

Artificial Intelligence · Computer Science 2024-10-23 Sizhe Ma , Katherine A. Flanigan , Mario Bergés

Dynamical system state estimation and parameter calibration problems are ubiquitous across science and engineering. Bayesian approaches to the problem are the gold standard as they allow for the quantification of uncertainties and enable…

Data Analysis, Statistics and Probability · Physics 2024-11-12 Kairui Hao , Ilias Bilionis

Robotic systems have become integral to smart environments, enabling applications ranging from urban surveillance and automated agriculture to industrial automation. However, their effective operation in dynamic settings - such as smart…

Deep learning models have created great opportunities for data-driven fault diagnosis but they require large amount of labeled failure data for training. In this paper, we propose to use a digital twin to support developing data-driven…

Machine Learning · Computer Science 2024-11-05 Killian Mc Court , Xavier Mc Court , Shijia Du , Zhiguo Zeng

Digital twins are sophisticated software systems for the representation, monitoring, and control of cyber-physical systems, including automotive, avionics, smart manufacturing, and many more. Existing definitions and reference models of…

Software Engineering · Computer Science 2025-07-08 Jerome Pfeiffer , Jingxi Zhang , Benoit Combemale , Judith Michael , Bernhard Rumpe , Manuel Wimmer , Andreas Wortmann

Digital Twins, virtual replicas of physical systems that enable real-time monitoring, model updates, predictions, and decision-making, present novel avenues for proactive control strategies for autonomous systems. However, achieving…

Systems and Control · Electrical Eng. & Systems 2025-05-08 Yi-Ping Chen , Ying-Kuan Tsai , Vispi Karkaria , Wei Chen

Digital Twins (DTs) are virtual representations of physical systems synchronized in real time through Internet of Things (IoT) sensors and computational models. In industrial applications, DTs enable predictive maintenance, fault diagnosis,…

Other Computer Science · Computer Science 2025-07-18 Ali Mohammad-Djafari

In many industries, the scale and complexity of systems can present significant barriers to the development of accurate digital twin models. This paper introduces a novel methodology and a modular computational tool utilizing machine…

Computational Engineering, Finance, and Science · Computer Science 2025-09-23 Deniz Karanfil , Bahram Ravani

Digital twins promise to enhance robotic manipulation by maintaining a consistent link between real-world perception and simulation. However, most existing systems struggle with the lack of a unified model, complex dynamic interactions, and…

Robotics · Computer Science 2026-03-06 Yichen Cai , Paul Jansonnie , Cristiana de Farias , Oleg Arenz , Jan Peters

The notion of duality -- that a given physical system can have two different mathematical descriptions -- is a key idea in modern theoretical physics. Establishing a duality in lattice statistical mechanics models requires the construction…

Statistical Mechanics · Physics 2024-11-08 Andrea E. V. Ferrari , Prateek Gupta , Nabil Iqbal

Recent digital advances have popularized predictive maintenance (PMx), offering enhanced efficiency, automation, accuracy, cost savings, and independence in maintenance processes. Yet, PMx continues to face numerous limitations such as poor…

Artificial Intelligence · Computer Science 2024-09-11 Sizhe Ma , Katherine A. Flanigan , Mario Bergés

Time-varying linear state-space models are powerful tools for obtaining mathematically interpretable representations of neural signals. For example, switching and decomposed models describe complex systems using latent variables that evolve…

We propose a synthesis method for the design of digital twins applicable to various systems (pneumatic, hydraulic, electrical/electronic circuits). The methodology allows representing the operation of these systems through an active digital…

Systems and Control · Electrical Eng. & Systems 2024-10-01 Veyis Gunes

While digital twins (DT) hold promise for providing real-time insights into complex energy assets, much of the current literature either does not offer a clear framework for information exchange between the model and the asset, lacks key…

Machine Learning · Computer Science 2025-07-03 Logan A. Burnett , Umme Mahbuba Nabila , Majdi I. Radaideh

Over the past decade, scientific machine learning has transformed the development of mathematical and computational frameworks for analyzing, modeling, and predicting complex systems. From inverse problems to numerical PDEs, dynamical…

Machine Learning · Computer Science 2025-09-26 Matthias Chung , Deepanshu Verma , Max Collins , Amit N. Subrahmanya , Varuni Katti Sastry , Vishwas Rao

Bayesian models quantify uncertainty and facilitate optimal decision-making in downstream applications. For most models, however, practitioners are forced to use approximate inference techniques that lead to sub-optimal decisions due to…

Machine Learning · Statistics 2019-09-12 Tomasz Kuśmierczyk , Joseph Sakaya , Arto Klami

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

This paper proposes a multitask learning framework for probabilistic model updating by jointly using strain and acceleration measurements. This framework can enhance the structural damage assessment and response prediction of existing steel…

Applications · Statistics 2024-02-01 Taro Yaoyama , Tatsuya Itoi , Jun Iyama

Shorter product life cycles and increasing individualization of production leads to an increased reconfiguration demand in the domain of industrial automation systems, which will be dominated by cyber-physical production systems in the…

Artificial Intelligence · Computer Science 2021-07-09 Timo Müller , Benjamin Lindemann , Tobias Jung , Nasser Jazdi , Michael Weyrich