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Models with intractable likelihood functions arise in areas including network analysis and spatial statistics, especially those involving Gibbs random fields. Posterior parameter es timation in these settings is termed a doubly-intractable…

Computation · Statistics 2018-10-16 Lampros Bouranis , Nial Friel , Florian Maire

We propose a \textit{guided multi-fidelity Bayesian optimization} framework for data-efficient controller tuning that integrates corrected digital twin simulations with real-world measurements. The method targets closed-loop systems with…

Robotics · Computer Science 2025-10-21 Mahdi Nobar , Jürg Keller , Alessandro Forino , John Lygeros , Alisa Rupenyan

Online joint estimation of unknown parameters and states in a dynamical system with uncertainty quantification is crucial in many applications. For example, digital twins dynamically update their knowledge of model parameters and states to…

Methodology · Statistics 2026-01-01 Liliang Wang , Alex Gorodetsky

Double machine learning is a statistical method for leveraging complex black-box models to construct approximately unbiased treatment effect estimates given observational data with high-dimensional covariates, under the assumption of a…

Machine Learning · Statistics 2022-06-03 Nitai Fingerhut , Matteo Sesia , Yaniv Romano

We propose a digital twin approach to improve healthcare decision support systems with a combination of domain knowledge and data. Domain knowledge helps build decision thresholds that doctors can use to determine a risk or recommend a…

Artificial Intelligence · Computer Science 2019-10-31 Dattaraj Jagdish Rao , Shraddha Mane

This paper presents a novel methodological framework, called the Actor-Simulator, that incorporates the calibration of digital twins into model-based reinforcement learning for more effective control of stochastic systems with complex…

Machine Learning · Computer Science 2025-01-07 Hua Zheng , Wei Xie , Ilya O. Ryzhov , Keilung Choy

One of the challenges in twinned systems is ensuring the digital twin remains a valid representation of the system it twins. Depending on the type of twinning occurring, it is either trivial, such as in dashboarding/visualizations that…

Software Engineering · Computer Science 2025-12-05 Joost Mertens , Joachim Denil

A digital twin contains up-to-date data-driven models of the physical world being studied and can use simulation to optimise the physical world. However, the analysis made by the digital twin is valid and reliable only when the model is…

Artificial Intelligence · Computer Science 2024-11-01 Nan Zhang , Rami Bahsoon , Nikos Tziritas , Georgios Theodoropoulos

Dual control explicitly addresses the problem of trading off active exploration and exploitation in the optimal control of partially unknown systems. While the problem can be cast in the framework of stochastic dynamic programming, exact…

Systems and Control · Electrical Eng. & Systems 2019-11-12 Elena Arcari , Lukas Hewing , Melanie N. Zeilinger

Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration of artificial intelligence technologies. This paper presents…

Deep neural networks has been increasingly applied in fault diagnostics, where it uses historical data to capture systems behavior, bypassing the need for high-fidelity physical models. However, despite their competence in prediction tasks,…

Machine Learning · Computer Science 2025-09-24 Arman Mohammadi , Mattias Krysander , Daniel Jung , Erik Frisk

Brain digital twins aim to provide faithful, individualized computational representations of brains as dynamical systems, enabling mechanistic understanding and supporting prediction of clinical interventions. Yet current approaches remain…

Computational Engineering, Finance, and Science · Computer Science 2026-04-16 Alexandre Muzy

The digital twin approach has gained recognition as a promising solution to the challenges faced by the Architecture, Engineering, Construction, Operations, and Management (AECOM) industries. However, its broader application across AECOM…

Applications · Statistics 2025-07-02 Dafydd Cotoarbă , Daniel Straub , Ian FC Smith

The design and operation of systems are conventionally viewed as a sequential decision-making process that is informed by data from physical experiments and simulations. However, the integration of these high-dimensional and heterogeneous…

Applications · Statistics 2025-03-04 Anton van Beek , Vispi Karkaria , Wei Chen

Digital twins (DTs), serving as the core enablers for real-time monitoring and predictive maintenance of complex cyber-physical systems, impose critical requirements on their virtual models: high predictive accuracy, strong…

Robotics · Computer Science 2026-01-16 He Ren , Gaowei Yan , Hang Liu , Lifeng Cao , Zhijun Zhao , Gang Dang

Most modeling approaches lie in either of the two categories: physics-based or data-driven. Recently, a third approach which is a combination of these deterministic and statistical models is emerging for scientific applications. To leverage…

Computational Physics · Physics 2021-03-29 Omer San , Adil Rasheed , Trond Kvamsdal

This paper proposes a sparse Bayesian treatment of deep neural networks (DNNs) for system identification. Although DNNs show impressive approximation ability in various fields, several challenges still exist for system identification…

Systems and Control · Electrical Eng. & Systems 2022-06-02 Hongpeng Zhou , Chahine Ibrahim , Wei Xing Zheng , Wei Pan

Digital twins are models of real-world systems that can simulate their dynamics in response to potential actions. In complex settings, the state and action variables, and available data and knowledge relevant to a system can constantly…

Computation and Language · Computer Science 2025-07-23 Harry Amad , Nicolás Astorga , Mihaela van der Schaar

Online optimisation facilitates the solution of dynamic inverse problems, such as image stabilisation, fluid flow monitoring, and dynamic medical imaging. In this paper, we improve upon previous work on predictive online primal-dual methods…

Optimization and Control · Mathematics 2025-02-28 Neil Dizon , Jyrki Jauhiainen , Tuomo Valkonen

A Bayesian data assimilation scheme is formulated for advection-dominated or hyperbolic evolutionary problems, and observations. The method is referred to as the dynamic likelihood filter because it exploits the model physics to dynamically…

Dynamical Systems · Mathematics 2017-04-26 Juan M. Restrepo