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We develop a speckle-tracking method for x-ray phase-contrast imaging, based on the concept of geometric flow. This flow is a conserved current associated with deformation of illuminating x-ray speckles induced by passage through a sample.…

Medical Physics · Physics 2018-11-14 David M. Paganin , Helene Labriet , Emmanuel Brun , Sebastien Berujon

In the last five decades, iterative phase retrieval methods draw large amount of interest across the research community as a non-interferometric approach to recover quantitative phase distributions from one (or more) intensity measurement.…

Optics · Physics 2020-07-21 Nathaniel Hai , Joseph Rosen

Scanning probe microscopy is one of the most versatile windows into the nanoworld, providing imaging access to a variety of sample properties, depending on the probe employed. Tunneling probes map electronic properties of samples, magnetic…

Mesoscale and Nanoscale Physics · Physics 2015-01-09 Thomas Häberle , Dominik Schmid-Lorch , Friedemann Reinhard , Jörg Wrachtrup

Phase contrast transmission electron microscopy (TEM) is a powerful tool for imaging the local atomic structure of materials. TEM has been used heavily in studies of defect structures of 2D materials such as monolayer graphene due to its…

Materials Science · Physics 2021-09-01 Robbie Sadre , Colin Ophus , Anstasiia Butko , Gunther H Weber

X-ray microscopy has been an indispensable tool to image nanoscale properties for materials research. One of its recent advances is to extend microscopic studies to the time domain for visualizing the dynamics of nanoscale phenomena.…

Mesoscale and Nanoscale Physics · Physics 2025-03-25 Haidan Wen , Mathew J. Cherukara , Martin V. Holt

Micro-focused X-ray beams produced by third generation synchrotron sources offer new perspective of studying strains and processes at nanoscale. Atomic force microscope setup combined with a micro-focused synchrotron beam allows precise…

Instrumentation and Detectors · Physics 2015-06-03 T. Slobodskyy , A. V. Zozulya , R. Tholapi , L. Liefeith , M. Fester , M. Sprung , W. Hansen

X-ray imaging is the most popular medical imaging technology. While x-ray radiography is rather cost-effective, tissue structures are superimposed along the x-ray paths. On the other hand, computed tomography (CT) reconstructs internal…

Medical Physics · Physics 2021-12-01 Chuang Niu , Ge Wang

Hard x-ray imaging is indispensable across diverse fields owing to its high penetrability. However, the resolution of traditional x-ray imaging modalities, such as computed tomography (CT) systems, is constrained by factors including beam…

Medical Physics · Physics 2024-02-23 O. Sefi , A. Ben Yehuda , Y. Klein , S. Bloch , H. Schwartz , E. Cohen , S. Shwartz

Amorphous, glass, and glass-ceramic materials practically always include a significant number (more than eight) of crystalline phases, with the contents of the latter ranging from a few wt.% to several hundredths or tenths of wt.%. The…

Holographic coherent X-ray imaging enables nanoscale imaging of biological cells and tissues, rendering both phase and absorption contrast, i.e. real and imaginary parts of the refractive index. Unlike the standard model, which assumes a…

Analysis of PDEs · Mathematics 2026-05-29 Thorsten Hohage , Milad Karimi , Björn Müller

Usually, lesions are not isolated but are associated with the surrounding tissues. For example, the growth of a tumour can depend on or infiltrate into the surrounding tissues. Due to the pathological nature of the lesions, it is…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Lin Wang , Xiufen Ye , Donghao Zhang , Wanji He , Lie Ju , Yi Luo , Huan Luo , Xin Wang , Wei Feng , Kaimin Song , Xin Zhao , Zongyuan Ge

Biological tissues are composed of discrete compartments of biochemical media that often exhibit subtle differences in refractive index. Light propagating through these compartments partially diffracts in a forward direction with a pi/2…

Optics · Physics 2025-05-12 Gregory N. McKay , Jerome Mertz , Nicholas J. Durr

Although defocus can be used to generate partial phase contrast in transmission electron microscope images, cryo-electron microscopy (cryo-EM) can be further improved by the development of phase plates which increase contrast by applying a…

Quantitative Methods · Quantitative Biology 2024-03-14 Jeremy J. Axelrod , Jessie T. Zhang , Petar N. Petrov , Robert M. Glaeser , Holger Mueller

In this paper, a new phase-retrieval algorithm from an X-ray schlieren image is proposed. The schlieren method allows phase-contrast imaging with an objective lens and a knife-edge filter placed at the back focal plane of the objective.…

In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field,…

Optics · Physics 2014-05-02 Guoan Zheng , Roarke Horstmeyer , Changhuei Yang

Thin filters and gas tight windows are used in Space to protect sensitive X-ray detectors from out-of-band electromagnetic radiation, low-energy particles, and molecular contamination. Though very thin and made of light materials, filters…

Instrumentation and Methods for Astrophysics · Physics 2023-05-24 Marco Barbera , Ugo Lo Cicero , Luisa Sciortino

Diffraction tomography is a widely used inverse scattering technique for quantitative imaging of weakly scattering media. In its conventional formulation, diffraction tomography assumes monochromatic plane wave illumination. This…

Numerical Analysis · Mathematics 2026-03-11 Peter Elbau , Noemi Naujoks , Otmar Scherzer

Cosmic rays interacting with the atmosphere result in a flux of secondary particles including muons and electrons. Atmospheric ray tomography (ART) uses the muons and electrons for detecting objects and their composition. This paper…

Noninvasive X-ray imaging of nanoscale three-dimensional objects, e.g. integrated circuits (ICs), generally requires two types of scanning: ptychographic, which is translational and returns estimates of complex electromagnetic field through…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Iksung Kang , Ziling Wu , Yi Jiang , Yudong Yao , Junjing Deng , Jeffrey Klug , Stefan Vogt , George Barbastathis
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