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Breast cancer is the most common cancer and is the leading cause of cancer death among women worldwide. Detection of breast cancer, while it is still small and confined to the breast, provides the best chance of effective treatment.…
We present a concept for an Advanced Compton Telescope (ACT) based on the use of pixelized gas micro-well detectors to form a three-dimensional electron track imager. A micro-well detector consists of an array of individual micro-patterned…
Radiotherapy treatment for prostate cancer relies on computed tomography (CT) and/or magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk (OARs). Manual segmentation of these volumes is regarded as the gold…
We exploit the near field enhancement of nano-antennas to investigate the Raman spectra of otherwise not optically detectable carbon nanotubes (CNTs). We demonstrate that a top-down fabrication approach is particularly promising when…
The purpose of the present work is the study of reconstruction properties of a new Molecular Breast Imaging (MBI) device for the early diagnosis of breast cancer, in Limited Angle Tomography (LAT), by using two asymmetric detector heads…
The purpose of this clinical study is to test broad spectral range (635-1060 nm) time domain diffuse optical spectroscopy in monitoring the response of breast cancer patients to neoadjuvant chemotherapy (NAC). The broadband operation allows…
Delineation of tumors and organs-at-risk permits detecting and correcting changes in the patients' anatomy throughout the treatment, making it a core step of adaptive proton therapy (APT). Although AI-based auto-contouring technologies have…
Heavily obscured accretion is believed to represent an important stage in the growth of supermassive black holes, and to play an important role in shaping the observed spectrum of the Cosmic X-ray Background (CXB). Hard X-ray (E$>$10 keV)…
Adaptive therapy (AT) is designed to postpone the emergence of drug resistance by exploiting evolutionary competition among tumor subclones. Most mathematical models of AT assume a binary population structure of drug-sensitive and…
Atom probe tomography (APT) provides the three-dimensional composition of materials at near-atomic length scales, achieving detection limits in the range of tens of atomic parts-per-million regardless of element type. APT requires the…
Enhanced-accuracy ion-range verification in real time shall enable a significant step forward in the use of therapeutic ion beams. Positron-emission tomography (PET) and prompt-gamma imaging (PGI) are two of the most promising and…
The Computed Tomography (CT) for diagnosis of lesions in human internal organs is one of the most fundamental topics in medical imaging. Low-dose CT, which offers reduced radiation exposure, is preferred over standard-dose CT, and therefore…
The deployment of artificial intelligence in medical imaging is hindered by high computational complexity and resource-intensive processing of volumetric data. Although chest computed tomography (CT) volumes offer richer diagnostic…
We present the joint NuSTAR and XMM-Newton spectral analysis in the 0.6-70 keV band of three candidate Compton thick (CT-) AGN selected in the 100-month Swift-BAT catalog. These objects were previously classified as CT-AGNs based on low…
Artificial intelligence represents a new frontier in human medicine that could save more lives and reduce the costs, thereby increasing accessibility. As a consequence, the rate of advancement of AI in cancer medical imaging and more…
Early detection of breast cancer can increase treatment efficiency. Architectural Distortion (AD) is a very subtle contraction of the breast tissue and may represent the earliest sign of cancer. Since it is very likely to be unnoticed by…
Early identification of head and neck cancer (HNC) patients who would experience significant anatomical change during radiotherapy (RT) is important to optimize patient clinical benefit and treatment resources. This study aims to assess the…
Photoacoustic (PA) computed tomography (PACT) shows great potentials in various preclinical and clinical applications. A great number of measurements are the premise that obtains a high-quality image, which implies a low imaging rate or a…
Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…
Nowadays U-net-like FCNs predominate various biomedical image segmentation applications and attain promising performance, largely due to their elegant architectures, e.g., symmetric contracting and expansive paths as well as lateral…