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Compton telescopes based on semiconductor technologies are being developed to explore the gamma-ray universe in an energy band 0.1--20 MeV, which is not well covered by the present or near-future gamma-ray telescopes. The key feature of…

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

We present a new metric that uses the spectral curvature (SC) above 10 keV to identify Compton-thick AGN in low-quality Swift BAT X-ray data. Using NuSTAR, we observe nine high SC-selected AGN. We find that high-sensitivity spectra show the…

225Ac is a valuable medical radionuclide for targeted alpha therapy, but 227Ac is an undesirable byproduct of an accelerator-based synthesis method under investigation. Sufficient detector sensitivity is critical for quantifying the trace…

Microwave imaging is emerging as a promising substitution diagnostic tool, for breast cancer detection. It has ignited the interest in the interaction of the microwaves with biological tissues and their respective effects on the human body…

Image and Video Processing · Electrical Eng. & Systems 2019-12-04 Vineeta Kumari , Gyanendra Sheoran , Tirupathiraju Kanumuri

We present the X-ray spectroscopic study of the Compton-thick (CT) active galactic nuclei (AGN) population within the $\textit{Chandra}$ Deep Field South (CDF-S) by using the deepest X-ray observation to date, the $\textit{Chandra}$ 7 Ms…

High Energy Astrophysical Phenomena · Physics 2019-09-18 A. Corral , I. Georgantopoulos , A. Akylas , P. Ranalli

The Nuclear Compton Telescope (NCT) is a balloon-borne Compton telescope designed for the study of astrophysical sources in the soft gamma-ray regime (200 keV--20 MeV). NCT's ten high-purity germanium crossed-strip detectors measure the…

Dosimetry in BNCT poses significant challenges due to the indirect effect of neutrons interacting with elements within the body and uncertainties associated with the uptake of boron compounds used in clinical practice. Current treatment…

Breast cancer (BC) remains a significant health threat, with no long-term cure currently available. Early detection is crucial, yet mammography interpretation is hindered by high false positives and negatives. With BC incidence projected to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Jai Vardhan , Taraka Satya Krishna Teja Malisetti

In this work, we report on the advantageous aspects of the i-TED Compton imager for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that…

The Compton camera is a gamma-ray imaging device developed in the 1970s. In the 1990s, the COMPTEL detector onboard the CGRO was the first to utilize a Compton camera for MeV all-sky survey observations. Recently, various Compton cameras…

Boron Neutron Capture Therapy (BNCT) is an innovative binary form of radiation therapy with high selectivity towards cancer tissue based on the neutron capture reaction 10B(n,$\alpha$)7Li, consisting in the exposition of patients to neutron…

We describe a code designed for hot media {(T $\ge$} a few 10$^4$ K), optically thick to Compton scattering. It computes the structure of a plane-parallel slab of gas in thermal and ionization equilibrium, illuminated on one side or on both…

Astrophysics · Physics 2009-09-25 Anne-Marie Dumont , Suzy Collin

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

Medical Physics · Physics 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

Attenuation and scatter correction (AC) is crucial for quantitative Positron Emission Tomography (PET) imaging. Recently, direct application of AC in the image domain using deep learning approaches has been proposed for the hybrid PET/MR…

Medical Physics · Physics 2022-06-30 Reza Jahangir , Alireza Kamali-Asl , Hossein Arabi

For optical coherence tomography angiography (OCTA) images, a limited scanning rate leads to a trade-off between field-of-view (FOV) and imaging resolution. Although larger FOV images may reveal more parafoveal vascular lesions, their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Weiwen Zhang , Dawei Yang , Haoxuan Che , An Ran Ran , Carol Y. Cheung , Hao Chen

The GammaTPC is an MeV-scale single-phase liquid argon time-projection-chamber gamma-ray telescope concept with a novel dual-scale pixel-based charge-readout system. It promises to enable a significant improvement in sensitivity to…

Instrumentation and Methods for Astrophysics · Physics 2023-01-25 M. Buuck , A. Mishra , E. Charles , N. Di Lalla , O. Hitchcock , M. E. Monzani , N. Omodei , T. Shutt

Trans-activating transcriptional activator (TAT), a cell-penetrating peptide, has been extensively used for facilitating cellular uptake and nuclear targeting of drug delivery systems. However, the positively charged TAT peptide usually…

Tissues and Organs · Quantitative Biology 2024-07-31 Xing Guo , Lin Wang , Kayla Duval , Jing Fan , Shaobing Zhou , Zi Chen

188Re is a beta- (Emax = 2.12 MeV) and gamma (155 keV) emitter. Since its chemistry is similar to that of the largely employed tracer, 99mTc, molecules of hyaluronic acid (HA) have been labelled with 188Re to produce a target specific…

Medical imaging faces challenges such as limited spatial resolution, interference from electronic noise and poor contrast-to-noise ratios. Photon Counting Computed Tomography (PCCT) has emerged as a solution, addressing these issues with…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Ana Carolina Alves , André Ferreira , Gijs Luijten , Jens Kleesiek , Behrus Puladi , Jan Egger , Victor Alves