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Peristalsis is the driving mechanism behind a broad array of biological and engineered flows. In peristaltic pumping, a wave-like contraction of the tube wall produces local changes in volume which induce flow. Net flow arises due to…

Fluid Dynamics · Physics 2025-10-29 Aaron Winn , Eleni Katifori

We consider a Stokes flow coupled with advective-diffusive transport in an evolving domain with boundary conditions allowing for inflow and outflow. The evolution of the domain is induced by the transport process, leading to a fully coupled…

Analysis of PDEs · Mathematics 2026-02-10 Kilian Hacker , Maria Neuss-Radu

We train active neural-network flow controllers using a deep learning PDE augmentation method to optimize lift-to-drag ratios in turbulent airfoil flows at Reynolds number $5\times10^4$ and Mach number 0.4. Direct numerical simulation and…

Fluid Dynamics · Physics 2025-10-09 Xuemin Liu , Tom Hickling , Jonathan F. MacArt

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

According to the conventional approach to model neural ensembles the extracellular environment has fixed ionic concentrations. However, in many cases the extracellular concentration of potassium ions can not be regarded as constant. That…

Disordered Systems and Neural Networks · Physics 2015-05-13 D. E. Postnov , F. Müller , R. B. Schuppner , L. Schimansky-Geier

Excitable media are ubiquitous in nature, and in such systems the local excitation tends to self-organize in traveling waves, or in rotating spiral-shaped patterns in two or three spatial dimensions. Examples include waves during a pandemic…

Dynamical Systems · Mathematics 2023-12-25 Marie Cloet , Louise Arno , Desmond Kabus , Joeri Van der Veken , Alexander V. Panfilov , Hans Dierckx

In this paper, we showcase how flow obstruction by a deformable object can lead to symmetry breaking in curved domains subject to angular acceleration. Our analysis is motivated by the deflection of the cupula, a soft tissue located in the…

Fluid Dynamics · Physics 2025-11-06 Javier Chico-Vázquez , Derek E. Moulton , Dominic Vella

We consider the problem of initiation of propagating wave in a one-dimensional excitable fiber. In the FitzHugh-Nagumo theory, the key role is played by ``critical nucleus'' and ``critical pulse'' solutions whose (center-)stable manifold is…

Pattern Formation and Solitons · Physics 2009-11-13 I. Idris , V. N. Biktashev

In this study, using non-equilibrium molecular dynamics simulation, the flow of water in deformed carbon nanotubes is studied for two water models TIP4P/2005 and SPC/FH. The results demonstrated a non-uniform dependence of the flow on the…

Flow control aims at modifying a natural flow state to reach an other flow state considered as advantageous. In this paper, active feedback flow separation control is investigated with two different closed-loop control strategies, involving…

Systems and Control · Electrical Eng. & Systems 2023-09-22 T. Arnoult , G. Acher , V. Nowinski , P. Vuillemin , C. Briat , P. Pernod , C. Ghouila-Houri , A. Talbi , E. Garnier , C. Poussot-Vassal

We study a system of nonlinear differential equations simulating transport phenomena in active media. The model we are interested in is a generalization of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in…

Pattern Formation and Solitons · Physics 2019-05-07 Aleksandra Gawlik , Vsevolod Vladimirov , Sergii Skurativskyi

We introduce a geometrical extension of the FitzHugh-Nagumo equations describing propagation of electrical impulses in nerve axons. In this extension, the axon is modeled as a warped cylinder, rather than a straight line, as is usually…

Analysis of PDEs · Mathematics 2021-05-12 Afroditi Talidou , Almut Burchard , Israel Michael Sigal

The influence of time delay in systems of two coupled excitable neurons is studied in the framework of the FitzHugh-Nagumo model. Time-delay can occur in the coupling between neurons or in a self-feedback loop. The stochastic…

Pattern Formation and Solitons · Physics 2009-11-13 E. Schoell , G. Hiller , P. Hoevel , M. A. Dahlem

We discuss the synchronization of coupled neurons which are modelled as FitzHugh-Nagumo systems. As smallest entity in a larger network, we focus on two diffusively coupled subsystems, which can be interpreted as two mutually interacting…

Chaotic Dynamics · Physics 2008-09-05 Philipp Hoevel , Markus A. Dahlem , Eckehard Schoell

Tissue fluidity regulates many critical biological processes, including embryonic development, wound healing, and cancer metastasis. In confluent epithelia, where cell packing fraction is effectively fixed, the prevailing paradigm…

Biological Physics · Physics 2026-03-09 Pradip K. Bera , Anh Q. Nguyen , Molly McCord , Dapeng Bi , Jacob Notbohm

The dynamics and deformations of immersed flexible fibers are at the heart of important industrial and biological processes, induce peculiar mechanical and transport properties in the fluids that contain them, and are the basis for novel…

Fluid Dynamics · Physics 2019-05-23 O. du Roure , A. Lindner , E. N. Nazockdast , M. J. Shelley

Complex fluids flow in complex ways in complex structures. Transport of water and various organic and inorganic molecules in the central nervous system are important in a wide range of biological and medical processes [C. Nicholson, and S.…

Biological Physics · Physics 2021-05-19 Yi Zhu , Shixin Xu , Robert S. Eisenberg , Huaxiong Huang

This work explores four nonlinear classical models of neural oscillators, the Hodgkin-Huxley model, the Fitzhugh-Nagumo model, the Morris-Lecar model, and the Hindmarsh-Rose model. Nonlinear contraction theory is used to develop observers…

Neurons and Cognition · Quantitative Biology 2013-10-03 Ranjeetha Bharath , Jean-Jacques Slotine

Self-regulation of living tissue as an example of self-organization phenomena in active fractal systems of biological, ecological, and social nature is under consideration. The characteristic feature of these systems is the absence of any…

Tissues and Organs · Quantitative Biology 2008-12-02 Wassily Lubashevsky , Ihor Lubashevsky , Reinhard Mahnke

We study optical response of a resonant medium possessing nonlinear coupling to external field driven by a few-cycle pump pulse sequence. We demonstrate the possibility to directly produce unipolar half-cycle pulses from the medium…