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Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

Soft Condensed Matter · Physics 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson

Active fluid droplets surrounded by oil can spontaneously develop circulatory flows. However, the dynamics of the surrounding oil and their influence on the active fluid remain poorly understood. To investigate interactions between the…

Fluid Dynamics · Physics 2021-05-27 Yen-Chen Chen , Brock Jolicoeur , Chih-Che Chueh , Kun-Ta Wu

In this article, we are interested in the behavior of a fully connected network of $N$ neurons, where $N$ tends to infinity. We assume that the neurons follow the stochastic FitzHugh-Nagumo model, whose specificity is the non-linearity with…

Probability · Mathematics 2024-02-14 Laetitia Colombani , Pierre Le Bris

We demonstrate that nonlocal coupling enables control of the collective stochastic dynamics in the regime of coherence resonance. The control scheme based on the nonlocal interaction properties is presented by means of numerical simulation…

Adaptation and Self-Organizing Systems · Physics 2025-07-15 Aleksey Ryabov , Elena Rybalova , Andrei Bukh , Tatiana E. Vadivasova , Vladimir V. Semenov

We study the dynamics of a reaction-diffusion system composed of two mutually coupled excitable fibers. We focus on the situation in which dynamical properties of the two fibers are not identical because of the parameter difference between…

Pattern Formation and Solitons · Physics 2021-01-29 Hiromichi Suetani , Tatsuo Yanagita , Kazuyuki Aihara

We study the nonlinear dynamics of two delay-coupled neural systems each modelled by excitable dynamics of FitzHugh-Nagumo type and demonstrate that bistability between the stable fixed point and limit cycle oscillations occurs for…

Pattern Formation and Solitons · Physics 2015-05-13 M. A. Dahlem , G. Hiller , A. Panchuk , E. Schoell

The Fitzhugh-Nagumo neuronal model is used to explore the influence of the electric field on thermosensitive neurons' dynamics. This study investigates how the electric field affects polarization modulation in cell media induced by changes…

Chaotic Dynamics · Physics 2025-02-13 Ediline L. F. Nguessap , Fernando F. Ferreira , Antonio C. Roque

We apply the framework of optimal nonlinear control to steer the dynamics of a whole-brain network of FitzHugh-Nagumo oscillators. Its nodes correspond to the cortical areas of an atlas-based segmentation of the human cerebral cortex, and…

Neurons and Cognition · Quantitative Biology 2021-09-08 Teresa Chouzouris , Nicolas Roth , Caglar Cakan , Klaus Obermayer

We examine the response of type II excitable neurons to trains of synaptic pulses, as a function of the pulse frequency and amplitude. We show that the resonant behavior characteristic of type II excitability, already described for harmonic…

Neurons and Cognition · Quantitative Biology 2015-06-26 Pablo Balenzuela , Javier M. Buldu , Marcos Casanova , Jordi Garcia-Ojalvo

We explore a biomimetic model that simulates a cell, with the internal cytoplasm represented by a two-dimensional circular domain and the external cortex by a surrounding ring, both modeled using FitzHugh-Nagumo systems. The external ring…

Pattern Formation and Solitons · Physics 2025-01-08 Daniel Cebrián-Lacasa , Marcin Leda , Andrew B. Goryachev , Lendert Gelens

We demonstrate the generation of diverse material flow regimes in nematic liquid cells as driven by time-variable active surface anchoring, including no-net flow, oscillatory flow, steady flow, and pulsating flow. Specifically, we…

Soft Condensed Matter · Physics 2025-01-07 Seyed Reza Seyednejad , Miha Ravnik

We develop a continuum theory to describe the collective dynamics of deformable epithelial cells, using two tensor order parameters to distinguish the force-generating active filaments in the cells from their shape. The theory demonstrates…

Soft Condensed Matter · Physics 2025-01-13 Mehrana R. Nejad , Julia M. Yeomans , Sumesh P Thampi

A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…

Soft Condensed Matter · Physics 2025-05-12 Rajsekhar Das , Xin Li , Sumit Sinha , D. Thirumalai

Flow networks are essential for both living organisms and enginneered systems. These networks often present complex dynamics controlled, at least in part, by their topology. Previous works have shown that topologically complex networks…

Soft Condensed Matter · Physics 2020-03-24 Miguel Ruiz-Garcia , Eleni Katifori

Motivated by recent experiments on intracellular calcium dynamics, we study the general issue of fluctuation-induced nucleation of waves in excitable media. We utilize a stochastic Fitzhugh-Nagumo model for this study, a spatially-extended…

Condensed Matter · Physics 2009-11-10 Herve Henry , Herbert Levine

Active transport such as fluid flow is sought in molecular communication to extend coverage, improve reliability, and mitigate interference. Flow models are often over-simplified, assuming one-dimensional diffusion with constant drift.…

Emerging Technologies · Computer Science 2024-10-30 Wayan Wicke , Tobias Schwering , Arman Ahmadzadeh , Vahid Jamali , Adam Noel , Robert Schober

It is well known that Electroencephalography(EEG) and the respective evoked potentials have deep implications corresponding to specific cognitive tasks and in the diagnosis of several diseases such as epilepsy and schizophrenia. Some recent…

Neurons and Cognition · Quantitative Biology 2007-05-23 I. Mitra

We investigate the synchronization dynamics of two coupled noise-driven FitzHugh-Nagumo systems, representing two neural populations. For certain choices of the noise intensities and coupling strength, we find cooperative stochastic…

Adaptation and Self-Organizing Systems · Physics 2025-07-29 Philipp Hövel , Sarang A. Shah , Markus A. Dahlem , Eckehard Schöll

We study, by means of extensive direct numerical simulations, the turbulent flow produced by a two-dimensional cellular forcing in a cubic box with periodic boundary conditions. In spite of the strong anisotropy of the forcing, we find that…

Fluid Dynamics · Physics 2022-11-22 S. Berti , G. Boffetta , S. Musacchio

A normalizing flow models a complex probability density as an invertible transformation of a simple base density. Flows based on either coupling or autoregressive transforms both offer exact density evaluation and sampling, but rely on the…

Machine Learning · Statistics 2019-12-03 Conor Durkan , Artur Bekasov , Iain Murray , George Papamakarios