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Related papers: FPGA-Based In-Vivo Calcium Image Decoding for Clos…

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In this paper, a real-time 105-channel data acquisition platform based on FPGA for imaging will be implemented for mm-wave imaging systems. PC platform is also realized for imaging results monitoring purpose. Mm-wave imaging expands our…

Hardware Architecture · Computer Science 2017-02-09 Chengkai Guo , Jason Y. Du

Calcium imaging permits optical measurement of neural activity. Since intracellular calcium concentration is an indirect measurement of neural activity, computational tools are necessary to infer the true underlying spiking activity from…

Machine Learning · Statistics 2017-11-07 Artur Speiser , Jinyao Yan , Evan Archer , Lars Buesing , Srinivas C. Turaga , Jakob H. Macke

Calcium imaging data promises to transform the field of neuroscience by making it possible to record from large populations of neurons simultaneously. However, determining the exact moment in time at which a neuron spikes, from a calcium…

Methodology · Statistics 2018-02-22 Sean Jewell , Toby Dylan Hocking , Paul Fearnhead , Daniela Witten

Calcium imaging is an essential tool to study the activity of neuronal populations. However, the high level of background fluorescence in images hinders the accurate identification of neurons and the extraction of neuronal activities. While…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Seungjae Han , Eun-Seo Cho , Inkyu Park , Kijung Shin , Young-Gyu Yoon

Photoacoustic (PA) imaging has been widely applied in both preclinical and clinical applications. With a significantly increasing number of data acquisition channels, fast and high-quality image reconstruction for real-time PA imaging is an…

Medical Physics · Physics 2024-08-20 Zijian Gao , Yuting Shen , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

This paper presents a comprehensive review of recent advances in deploying convolutional neural networks (CNNs) for object detection, classification, and tracking on Field Programmable Gate Arrays (FPGAs). With the increasing demand for…

Hardware Architecture · Computer Science 2025-09-05 Safa Mohammed Sali , Mahmoud Meribout , Ashiyana Abdul Majeed

Two-photon imaging of calcium indicators allows simultaneous recording of responses of hundreds of neurons over hours and even days, but provides a relatively indirect measure of their spiking activity. Existing deconvolution algorithms…

Neurons and Cognition · Quantitative Biology 2016-01-05 Elad Ganmor , Michael Krumin , Luigi F. Rossi , Matteo Carandini , Eero P. Simoncelli

Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

Methodology · Statistics 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

Mitochondrial calcium handling is a particularly active research area in the neuroscience field, as it plays key roles in the regulation of several functions of the central nervous system, such as synaptic transmission and plasticity,…

Neurons and Cognition · Quantitative Biology 2024-08-23 Roman Serrat , Alexandre Oliveira-Pinto , Giovanni Marsicano , Sandrine Pouvreau

Widefield calcium imaging has recently emerged as a powerful experimental technique to record coordinated large-scale brain activity. These measurements present a unique opportunity to characterize spatiotemporal coherent structures that…

Neurons and Cognition · Quantitative Biology 2021-09-07 Nathaniel J Linden , Dennis R Tabuena , Nicholas A Steinmetz , William J Moody , Steven L Brunton , Bingni W Brunton

Oscillations in the local field potential (LFP) of the brain are key signatures of neural information processing. Perturbing these oscillations at specific phases in order to alter neural information processing is an area of active…

Signal Processing · Electrical Eng. & Systems 2021-03-17 Christopher Thomas , Thilo Womelsdorf

As the complexity of the scan algorithm is dependent on the number of design registers, large SoC scan designs can no longer be verified in RTL simulation unless partitioned into smaller sub-blocks. This paper proposes a methodology to…

Other Computer Science · Computer Science 2014-09-12 Bill Jason Tomas , Yingtao Jiang , Mei Yang

Optical imaging of genetically encoded calcium indicators is a powerful tool to record the activity of a large number of neurons simultaneously over a long period of time from freely behaving animals. However, determining the exact time at…

Applications · Statistics 2021-03-08 Tong Shen , Kevin Johnston , Gyorgy Lur , Michele Guindani , Hernando Ombao , Zhaoxia Yu

Recent work suggests that large-scale, multi-animal modeling can significantly improve neural recording analysis. However, for functional calcium traces, existing approaches remain task-specific, limiting transfer across common neuroscience…

Quantitative Methods · Quantitative Biology 2026-04-09 Xinhong Xu , Yimeng Zhang , Qichen Qian , Yuanlong Zhang

Calcium imaging allows for the parallel measurement of large neuronal populations in a spatially resolved and minimally invasive manner, and has become a gold-standard for neuronal functionality. While deep generative models have been…

Neurons and Cognition · Quantitative Biology 2025-10-02 Berta Ros , Mireia Olives-Verger , Caterina Fuses , Josep M Canals , Jordi Soriano , Jordi Abante

High-speed optical imaging of dynamic neuronal activity is essential yet challenging in neuroscience. While calcium imaging has been firmly established as a workhorse technique for monitoring neuronal activity, its limited temporal…

Denoising is a core operation in modern video pipelines. In codecs, in-loop filters suppress sensor noise and quantisation artefacts to improve rate-distortion performance; in cinema post-production, denoisers are used for restoration,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-07 Changhong Li , Clément Bled , Rosa Fernandez , Shreejith Shanker

We develop and study FPGA implementations of algorithms for charged particle tracking based on graph neural networks. The two complementary FPGA designs are based on OpenCL, a framework for writing programs that execute across heterogeneous…

An optical flow gradient algorithm was applied to spontaneously forming net- works of neurons and glia in culture imaged by fluorescence optical microscopy in order to map functional calcium signaling with single pixel resolution. Optical…

Computational Engineering, Finance, and Science · Computer Science 2010-01-22 Marius Buibas , Diana Yu , Krystal Nizar , Gabriel A. Silva

Calcium imaging has become a powerful and popular technique to monitor the activity of large populations of neurons in vivo. However, for ethical considerations and despite recent technical developments, recordings are still constrained to…

Neurons and Cognition · Quantitative Biology 2023-02-07 Bryan M. Li , Theoklitos Amvrosiadis , Nathalie Rochefort , Arno Onken