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Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…
Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…
Positronium-based imaging requires realistic modelling of positronium (Ps) decay in matter. We introduce a modular Ps decay model implemented in GATE 9.4 and GATE 10, enabling the definition of an arbitrary number of decay channels…
This paper reviewed the machine learning-based studies for quantitative positron emission tomography (PET). Specifically, we summarized the recent developments of machine learning-based methods in PET attenuation correction and low-count…
Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…
Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…
Plastic scintillators (PSs)embedded with wavelength-shifting fibers are widely used in high-energy particle physics, such as in muon taggers,as well as in medical physics and other applications. In this study,a simulation package was built…
GePEToS is a simulation framework developed over the last few years for assessing the instrumental performance of future PET scanners. It is based on Geant4, written in Object-Oriented C++ and runs on Linux platforms. The validity of…
Current clinical PET systems utilize detectors where the scintillator typically contains single elements of 3 - 6 mm width and about 20 mm height. While providing good TOF performance, this design limits the spatial resolution and causes…
Image registration is a fundamental technique in the analysis of longitudinal and multi-phase CT images within clinical practice. However, most existing methods are tailored for single-organ applications, limiting their generalizability to…
Prostate cancer is the most common disease in men and the second leading cause of death from cancer. Generic large imaging instruments used in cancer diagnosis have sensitivity, spatial resolution, and contrast inadequate for the task of…
The TT-PET collaboration is developing an MRI-compatible small animal PET scanner in which the sensitive element is a monolithic silicon pixel ASIC targeting 30 ps RMS time resolution. The photon-detection technique is based on a stack of…
Studies of the human brain during natural activities, such as locomotion, would benefit from the ability to image deep brain structures during these activities. While Positron Emission Tomography (PET) can image these structures, the bulk…
We are investigating a prototype virtual pinhole positron emission tomography (VP-PET) system for small animal imaging applications. The PET detector modules were made up of 1.3 mm lutetium-yttrium oxyorthosilicate (LYSO) arrays, and the…
The fast scintillation decay time and the high scintillation yield of liquid xenon makes it an appropriate material for nuclear medicine. Moreover, being a continuous medium with a uniform response, liquid xenon allows one to avoid most of…
Positron emission tomography (PET) scanners continue to increase sensitivity and axial coverage by adding an ever expanding array of block detectors. As they age, one or more block detectors may lose sensitivity due to a malfunction or…
Numerous oncology indications have extensively quantified metabolically active tumors using positron emission tomography (PET) and computed tomography (CT). F-fluorodeoxyglucose-positron emission tomography (FDG-PET) is frequently utilized…
Upright position CT scans make it possible for full-length-body imaging at conditions more relevant to daily situations, but the substantial weight of the upright CT scanners increases the risks to floor's stability and patients'safety.…
Introduction: Terbium-149 ($^{149}$Tb) is a promising radionuclide for targeted $\alpha$ therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low positron branching fraction and multiple prompt…
Building large-scale foundation model for PET imaging is hindered by limited access to labeled data and insufficient computational resources. To overcome data scarcity and efficiency limitations, we propose ALL-PET, a low-resource, low-shot…