Related papers: Signal enhancement for two-dimensional cryo-EM dat…
Weak-signal detection and single-particle selection from low-contrast micrographs of frozen hydrated biomolecules by cryo-electron microscopy (cryo-EM) presents a practical challenge. Cryo-EM image contrast degrades as the size of…
Error-control-coding (ECC) techniques are widely used in modern digital communication systems to minimize the effect of noisy channels on the quality of received signals. Motivated by the fact that both communication and imaging can be…
We propose a novel method of efficient upsampling of a single natural image. Current methods for image upsampling tend to produce high-resolution images with either blurry salient edges, or loss of fine textural detail, or spurious noise…
Cryo-electron microscopy (cryo-EM), the subject of the 2017 Nobel Prize in Chemistry, is a technology for determining the 3-D structure of macromolecules from many noisy 2-D projections of instances of these macromolecules, whose…
Discovering the 3D atomic structure of molecules such as proteins and viruses is a fundamental research problem in biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising vision-based technique for structure estimation which…
In this paper we study the formal algebraic structure underlying the intrinsic classification algorithm, recently introduced by Hadani, Shkolnisky, Singer and Zhao, for classifying noisy projection images of similar viewing directions in…
Low-light images suffer from severe noise and low illumination. Current deep learning models that are trained with real-world images have excellent noise reduction, but a ratio parameter must be chosen manually to complete the enhancement…
The growing role of data-driven approaches to scientific discovery has unveiled a large class of models that involve latent transformations with a rigid algebraic constraint. Three-dimensional molecule reconstruction in Cryo-Electron…
Particle picking is a crucial first step in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM). Selecting particles from the micrographs is difficult especially for small particles with low contrast. As…
Cryo-electron microscopy (Cryo-EM) enables high-resolution imaging of biomolecules, but structural heterogeneity remains a major challenge in 3D reconstruction. Traditional methods assume a discrete set of conformations, limiting their…
Cryo-electron microscopy (cryo-EM) has become a major experimental technique to determine the structures of large protein complexes and molecular assemblies, as evidenced by the 2017 Nobel Prize. Although cryo-EM has been drastically…
The construction of large-scale, high-quality datasets is a fundamental prerequisite for developing robust and generalizable foundation models in motor imagery (MI)-based brain-computer interfaces (BCIs). However, EEG signals collected from…
A multi-imaging strategy is proposed and experimentally tested to improve the accuracy of photon counting with an electron multiplying charge-coupled device (EMCCD), by taking into account the random nature of its on-chip gain and the…
Cryogenic electron microscopy (cryo-EM) is an invaluable technique for determining high-resolution three-dimensional structures of biological macromolecules using transmission particle images. The inherent symmetry in these macromolecules…
Multifarious image enhancement algorithms have been used in different applications. Still, some algorithms or modules are imperfect for practical use. When the image enhancement modules have been fixed or combined by a series of algorithms,…
Cryo-electron microscopy (cryo-EM) is an indispensable technique for determining the 3D structures of dynamic biomolecular complexes. While typically applied to image a single molecular species, cryo-EM has the potential for structure…
Due to numerous hardware shortcomings, medical image acquisition devices are susceptible to producing low-quality (i.e., low contrast, inappropriate brightness, noisy, etc.) images. Regrettably, perceptually degraded images directly impact…
Single-particle cryo-EM has transformed structural biology but still faces challenges in resolving conformational heterogeneity at atomic resolution. Existing cryo-EM heterogeneity analysis methods either lack atomic details or tend to…
Capturing images under extremely low-light conditions poses significant challenges for the standard camera pipeline. Images become too dark and too noisy, which makes traditional enhancement techniques almost impossible to apply. Recently,…
When one captures images in low-light conditions, the images often suffer from low visibility. This poor quality may significantly degrade the performance of many computer vision and multimedia algorithms that are primarily designed for…