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Recent success in training deep neural networks have prompted active investigation into the features learned on their intermediate layers. Such research is difficult because it requires making sense of non-linear computations performed by…

Machine Learning · Computer Science 2016-03-01 Yixuan Li , Jason Yosinski , Jeff Clune , Hod Lipson , John Hopcroft

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Deep neural networks are often seen as different from other model classes by defying conventional notions of generalization. Popular examples of anomalous generalization behaviour include benign overfitting, double descent, and the success…

Machine Learning · Computer Science 2025-07-11 Andrew Gordon Wilson

Prevention of secondary brain injury is a core aim of neurocritical care, with Spreading Depolarizations (SDs) recognized as a significant independent cause. SDs are typically monitored through invasive, high-frequency electrocorticography…

Signal Processing · Electrical Eng. & Systems 2025-05-20 Jeanne Boyer-Chammard , Yinzhe Wu , Chenyu Zhang , Sharon Jewell , Anthony Strong , Guang Yang , Martyn Boutelle

In one-class novelty detection, a model learns solely on the in-class data to single out out-class instances. Autoencoder (AE) variants aim to compactly model the in-class data to reconstruct it exclusively, thus differentiating the…

Machine Learning · Computer Science 2022-07-25 Jaewoo Park , Yoon Gyo Jung , Andrew Beng Jin Teoh

We present a framework for the unsupervised learning of neurosymbolic encoders, which are encoders obtained by composing neural networks with symbolic programs from a domain-specific language. Our framework naturally incorporates symbolic…

Machine Learning · Computer Science 2022-12-22 Eric Zhan , Jennifer J. Sun , Ann Kennedy , Yisong Yue , Swarat Chaudhuri

Deep neural networks usually benefit from unsupervised pre-training, e.g. auto-encoders. However, the classifier further needs supervised fine-tuning methods for good discrimination. Besides, due to the limits of full-connection, the…

Computer Vision and Pattern Recognition · Computer Science 2016-05-10 Hailin Shi , Xiangyu Zhu , Zhen Lei , Shengcai Liao , Stan Z. Li

Despite their black-box nature, deep learning models are extensively used in image-based drug discovery to extract feature vectors from single cells in microscopy images. To better understand how these networks perform representation…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Vivek Gopalakrishnan , Jingzhe Ma , Zhiyong Xie

Unsupervised anomaly detection (UAD) has been widely implemented in industrial and medical applications, which reduces the cost of manual annotation and improves efficiency in disease diagnosis. Recently, deep auto-encoder with its variants…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Mingqing Wang , Jiawei Li , Zhenyang Li , Chengxiao Luo , Bin Chen , Shu-Tao Xia , Zhi Wang

Deep learning for decoding EEG signals has gained traction, with many claims to state-of-the-art accuracy. However, despite the convincing benchmark performance, successful translation to real applications is limited. The frequent…

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

We introduce Constr-DRKM, a deep kernel method for the unsupervised learning of disentangled data representations. We propose augmenting the original deep restricted kernel machine formulation for kernel PCA by orthogonality constraints on…

Machine Learning · Computer Science 2020-12-01 Francesco Tonin , Panagiotis Patrinos , Johan A. K. Suykens

Neural networks pose a privacy risk due to their propensity to memorise and leak training data. We show that unique features occurring only once in training data are memorised by discriminative multi-layer perceptrons and convolutional…

Machine Learning · Computer Science 2022-05-23 John Hartley , Sotirios A. Tsaftaris

Shortcut learning, i.e., a model's reliance on undesired features not directly relevant to the task, is a major challenge that severely limits the applications of machine learning algorithms, particularly when deploying them to assist in…

Machine Learning · Computer Science 2025-06-17 Lukas Kuhn , Sari Sadiya , Jorg Schlotterer , Florian Buettner , Christin Seifert , Gemma Roig

Systems neuroscience relies on two complementary views of neural data, characterized by single neuron tuning curves and analysis of population activity. These two perspectives combine elegantly in neural latent variable models that…

Brain folding patterns have been reported to carry clinically relevant information. The brain folds mainly during the last trimester of pregnancy, and the process might be durably disturbed by preterm birth. Yet little is known about…

Neurons and Cognition · Quantitative Biology 2024-05-15 Julien Laval , Aymeric Gaudin , Vincent Frouin , Jessica Dubois , Andrea Gondova , Jean-François Mangin , Joël Chavas , Denis Rivière

Supervised learning has become a cornerstone of modern machine learning, yet a comprehensive theory explaining its effectiveness remains elusive. Empirical phenomena, such as neural analogy-making and the linear representation hypothesis,…

Machine Learning · Computer Science 2025-02-26 Patrik Reizinger , Alice Bizeul , Attila Juhos , Julia E. Vogt , Randall Balestriero , Wieland Brendel , David Klindt

This work investigates a practical and novel method for automated unsupervised fault detection in vehicles using a fully convolutional autoencoder. The results demonstrate the algorithm we developed can detect anomalies which correspond to…

Machine Learning · Computer Science 2024-09-10 Anthony Geglio , Eisa Hedayati , Mark Tascillo , Dyche Anderson , Jonathan Barker , Timothy C. Havens

We present a weakly supervised deep learning model for classifying thoracic diseases and identifying abnormalities in chest radiography. In this work, instead of learning from medical imaging data with region-level annotations, our model…

Computer Vision and Pattern Recognition · Computer Science 2018-11-07 Bo Zhou , Yuemeng Li , Jiangcong Wang

Universal anomaly detection still remains a challenging problem in machine learning and medical image analysis. It is possible to learn an expected distribution from a single class of normative samples, e.g., through epistemic uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Johanna P. Müller , Matthew Baugh , Jeremy Tan , Mischa Dombrowski , Bernhard Kainz