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This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

Training deep networks for semantic segmentation requires large amounts of labeled training data, which presents a major challenge in practice, as labeling segmentation masks is a highly labor-intensive process. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Lukas Hoyer , Dengxin Dai , Yuhua Chen , Adrian Köring , Suman Saha , Luc Van Gool

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

Histopathology image analysis is critical yet challenged by the demand of segmenting tissue regions and nuclei instances for tumor microenvironment and cellular morphology analysis. Existing studies focused on tissue semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Qing Xu , Wenting Duan , Zhen Chen

Scribble-supervised medical image segmentation tackles the limitation of sparse masks. Conventional approaches alternate between: labeling pseudo-masks and optimizing network parameters. However, such iterative two-stage paradigm is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Zefan Yang , Di Lin , Dong Ni , Yi Wang

The scarcity of labeled data often impedes the application of deep learning to the segmentation of medical images. Semi-supervised learning seeks to overcome this limitation by exploiting unlabeled examples in the learning process. In this…

Computer Vision and Pattern Recognition · Computer Science 2021-06-25 Jizong Peng , Marco Pedersoli , Christian Desrosiers

Self-supervised contrastive learning is an effective approach for addressing the challenge of limited labelled data. This study builds upon the previously established two-stage patch-level, multi-label classification method for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Salma Haidar , José Oramas

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

Automatic skin lesion segmentation on dermoscopic images is an essential component in computer-aided diagnosis of melanoma. Recently, many fully supervised deep learning based methods have been proposed for automatic skin lesion…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Pheng-Ann Heng

Semi-supervised learning has been employed to alleviate the need for extensive labeled data for histopathology image segmentation, but existing methods struggle with noisy pseudo-labels due to ambiguous gland boundaries and morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Thien Nguyen , Daisuke Kihara , Tianyang Wang , Xingjian Li , Min Xu

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Training deep networks for semantic segmentation requires large amounts of labeled training data, which presents a major challenge in practice, as labeling segmentation masks is a highly labor-intensive process. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Lukas Hoyer , Dengxin Dai , Qin Wang , Yuhua Chen , Luc Van Gool

The scarcity of labeled data often limits the application of supervised deep learning techniques for medical image segmentation. This has motivated the development of semi-supervised techniques that learn from a mixture of labeled and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Gerda Bortsova , Florian Dubost , Laurens Hogeweg , Ioannis Katramados , Marleen de Bruijne

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

We present our novel deep multi-task learning method for medical image segmentation. Existing multi-task methods demand ground truth annotations for both the primary and auxiliary tasks. Contrary to it, we propose to generate the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Binod Bhattarai , Ronast Subedi , Rebati Raman Gaire , Eduard Vazquez , Danail Stoyanov

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Medical ultrasound imaging is ubiquitous, but manual analysis struggles to keep pace. Automated segmentation can help but requires large labeled datasets, which are scarce. Semi-supervised learning leveraging both unlabeled and limited…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Yaxiong Chen , Yujie Wang , Zixuan Zheng , Jingliang Hu , Yilei Shi , Shengwu Xiong , Xiao Xiang Zhu , Lichao Mou