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Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of cerebrovascular diseases such as Moyamoya, carotid stenosis, aneurysms, and stroke. Positron emission tomography (PET) is currently…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Ramy Hussein , Moss Zhao , David Shin , Jia Guo , Kevin T. Chen , Rui D. Armindo , Guido Davidzon , Michael Moseley , Greg Zaharchuk

Magnetic resonance imaging (MRI) and positron emission tomography (PET) are increasingly used in multimodal analysis of neurodegenerative disorders. While MRI is broadly utilized in clinical settings, PET is less accessible. Many studies…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Minhui Yu , Mengqi Wu , Ling Yue , Andrea Bozoki , Mingxia Liu

Positron Emission Tomography (PET) is an imaging method that can assess physiological function rather than structural disturbances by measuring cerebral perfusion or glucose consumption. However, this imaging technique relies on injection…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Sahar Yousefi , Hessam Sokooti , Wouter M. Teeuwisse , Dennis F. R. Heijtel , Aart J. Nederveen , Marius Staring , Matthias J. P. van Osch

Perfusion MRI is an important modality in many brain imaging protocols, since it probes cerebrovascular changes in aging and many diseases; however, it may not be always available. Here we introduce a method that seeks to estimate regional…

Image and Video Processing · Electrical Eng. & Systems 2019-11-20 Ganesh B Chand , Mohamad Habes , Sudipto Dolui , John A Detre , David A Wolk , Christos Davatzikos

Purpose: Arterial spin labeling (ASL) perfusion imaging indicates direct and absolute measurement of cerebral blood flow (CBF). Arterial transit time (ATT) is a related physiological parameter reflecting the duration for the labeled spins…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Yiran Li , Ze Wang

MRI and PET are crucial diagnostic tools for brain diseases, as they provide complementary information on brain structure and function. However, PET scanning is costly and involves radioactive exposure, resulting in a lack of PET. Moreover,…

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

Significance: Measuring cerebral blood flow (CBF) is crucial for diagnosing various cerebral diseases. An affordable, wearable, and fiber-free continuous-wave speckle contrast flowmetry (CW-DSCF) technique has been developed for continuous…

Quantitative Methods · Quantitative Biology 2025-02-13 Chaebeom Yeo , Xuhui Liu , Mehrana Mohtasebi , Faezeh Akbari , Faraneh Fathi , Guoqiang Yu

Speckle contrast optical spectroscopy (SCOS) offers a non-invasive and cost-effective method for monitoring cerebral blood flow (CBF). However, extracting accurate CBF from SCOS necessitates precise noise pre-calibration. Errors from this…

Signal Processing · Electrical Eng. & Systems 2025-06-23 Ninghe Liu , Yu Xi Huang , Simon Mahler , Changhuei Yang

In the realm of cerebrovascular monitoring, primary metrics typically include blood pressure, which influences cerebral blood flow (CBF) and is contingent upon vessel radius. Measuring CBF non-invasively poses a persistent challenge,…

Attenuation correction (AC) is essential for the generation of artifact-free and quantitatively accurate positron emission tomography (PET) images. However, AC of PET faces challenges including inter-scan motion and erroneous transformation…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Yu Guan , Bohui Shen , Xinchong Shi , Xiangsong Zhang , Bingxuan Li , Qiegen Liu

Early diagnosis and intervention are clinically considered the paramount part of treating cerebral palsy (CP), so it is essential to design an efficient and interpretable automatic prediction system for CP. We highlight a significant…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Haozheng Zhang , Hubert P. H. Shum , Edmond S. L. Ho

Head movement poses a significant challenge in brain positron emission tomography (PET) imaging, resulting in image artifacts and tracer uptake quantification inaccuracies. Effective head motion estimation and correction are crucial for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Zhuotong Cai , Tianyi Zeng , Jiazhen Zhang , Eléonore V. Lieffrig , Kathryn Fontaine , Chenyu You , Enette Mae Revilla , James S. Duncan , Jingmin Xin , Yihuan Lu , John A. Onofrey

[$^{18}$F]fluorodeoxyglucose (FDG) positron emission tomography (PET) has emerged as a crucial tool in identifying the epileptic focus, especially in cases where magnetic resonance imaging (MRI) diagnosis yields indeterminate results. FDG…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Wentao Chen , Jiwei Li , Xichen Xu , Hui Huang , Siyu Yuan , Miao Zhang , Tianming Xu , Jie Luo , Weimin Zhou

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Measurement of head biometrics from fetal ultrasonography images is of key importance in monitoring the healthy development of fetuses. However, the accurate measurement of relevant anatomical structures is subject to large inter-observer…

Dynamic positron emission tomography (PET) and kinetic modeling are pivotal in advancing tracer development research in small animal studies. Accurate kinetic modeling requires precise input function estimation, traditionally achieved via…

While Positron emission tomography (PET) imaging has been widely used in diagnosis of number of diseases, it has costly acquisition process which involves radiation exposure to patients. However, magnetic resonance imaging (MRI) is a safer…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Hajar Emami , Qiong Liu , Ming Dong

The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-03 Fuyou Mao , Lixin Lin , Ming Jiang , Dong Dai , Chao Yang , Hao Zhang , Yan Tang

Myocardial blood flow (MBF) and flow reserve are usually quantified in the clinic with positron emission tomography (PET) using a perfusion-specific radiotracer (e.g. 82Rbchloride). However, the clinical accessibility of existing perfusion…

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