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The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

Big-data-based artificial intelligence (AI) supports profound evolution in almost all of science and technology. However, modeling and forecasting multi-physical systems remain a challenge due to unavoidable data scarcity and noise.…

Machine Learning · Computer Science 2022-02-08 Pengpeng Shi , Zhi Zeng , Tianshou Liang

We employ physics-informed neural networks (PINNs) to infer properties of biological materials using synthetic data. In particular, we successfully apply PINNs on inferring the thrombus permeability and visco-elastic modulus from thrombus…

Computational Physics · Physics 2021-01-22 Minglang Yin , Xiaoning Zheng , Jay D. Humphrey , George Em Karniadakis

Physics-Informed Neural Networks (PINNs) have emerged as a highly active research topic across multiple disciplines in science and engineering, including computational geomechanics. PINNs offer a promising approach in different applications…

Computational Engineering, Finance, and Science · Computer Science 2024-04-30 Yared W. Bekele

Physics-informed neural networks (PINNs) are demonstrating remarkable promise in integrating physical models with gappy and noisy observational data, but they still struggle in cases where the target functions to be approximated exhibit…

Machine Learning · Computer Science 2021-06-16 Sifan Wang , Hanwen Wang , Paris Perdikaris

Successfully training Physics Informed Neural Networks (PINNs) for highly nonlinear PDEs on complex 3D domains remains a challenging task. In this paper, PINNs are employed to solve the 3D incompressible Navier-Stokes (NS) equations at…

Computational Engineering, Finance, and Science · Computer Science 2024-08-23 Saakaar Bhatnagar , Andrew Comerford , Araz Banaeizadeh

Physics informed neural networks have been gaining popularity due to their unique ability to incorporate physics laws into data-driven models, ensuring that the predictions are not only consistent with empirical data but also align with…

Populations and Evolution · Quantitative Biology 2025-01-30 Dinh Viet Cuong , Branislava Lalić , Mina Petrić , Binh Nguyen , Mark Roantree

Physics-informed neural networks (PINNs) are a newly emerging research frontier in machine learning, which incorporate certain physical laws that govern a given data set, e.g., those described by partial differential equations (PDEs), into…

Neural and Evolutionary Computing · Computer Science 2023-07-11 Bo Wang , A. K. Qin , Sajjad Shafiei , Hussein Dia , Adriana-Simona Mihaita , Hanna Grzybowska

For decades, solutions to regional scale landslide prediction have mostly relied on data-driven models, by definition, disconnected from the physics of the failure mechanism. The success and spread of such tools came from the ability to…

Geophysics · Physics 2024-12-04 Ashok Dahal , Luigi Lombardo

Neural networks can be trained to solve partial differential equations (PDEs) by using the PDE residual as the loss function. This strategy is called "physics-informed neural networks" (PINNs), but it currently cannot produce high-accuracy…

Machine Learning · Computer Science 2024-04-11 Qi Zeng , Yash Kothari , Spencer H. Bryngelson , Florian Schäfer

Physics-informed neural networks (PINNs) provide a powerful framework for learning governing equations of dynamical systems from data. Biologically-informed neural networks (BINNs) are a variant of PINNs that preserve the known differential…

Machine Learning · Computer Science 2026-04-21 William Lavery , Jodie A. Cochrane , Christian Olesen , Dagim S. Tadele , John T. Nardini , Sara Hamis

In many scientific and engineering (e.g., physical, biochemical, medical) practices, data generated through expensive experiments or large-scale simulations, are often sparse and noisy. Physics-informed neural network (PINN) incorporates…

Machine Learning · Computer Science 2025-10-21 Kai-liang Lu

Machine learning techniques have proven to be effective in addressing the structure of atomic nuclei. Physics$-$Informed Neural Networks (PINNs) are a promising machine learning technique suitable for solving integro-differential problems…

Computational Physics · Physics 2026-02-13 Lorenzo Brevi , Antonio Mandarino , Carlo Barbieri , Enrico Prati

In this paper, we develop a deep learning approach for the accurate solution of challenging problems of near-field microscopy that leverages the powerful framework of physics-informed neural networks (PINNs) for the inversion of the complex…

Optics · Physics 2024-06-12 Yuyao Chen , Luca Dal Negro

This work addresses the development of a physics-informed neural network (PINN) with a loss term derived from a discretized time-dependent reduced-order system. In this work, first, the governing equations are discretized using a finite…

Numerical Analysis · Mathematics 2024-01-30 Rahul Halder , Giovanni Stabile , Gianluigi Rozza

Previous research in the scientific field has utilized statistical empirical models and machine learning to address fitting challenges. While empirical models have the advantage of numerical generalization, they often sacrifice accuracy.…

Computational Engineering, Finance, and Science · Computer Science 2025-02-13 Po-Han Hou , Sung-Chi Hsieh

State estimation is a cornerstone of power system control-center operations, and its robust operation is increasingly a cyber-physical security concern as modern grids become more digitalized and communication-intensive. Neural…

Machine Learning · Computer Science 2026-04-28 Solon Falas , Markos Asprou , Charalambos Konstantinou , Maria K. Michael

Physics-Informed Neural Networks (PINNs) have emerged as a promising computational framework for solving differential equations by integrating deep learning with physical constraints. However, their application in gas turbines is still in…

Computational Engineering, Finance, and Science · Computer Science 2025-06-25 Afila Ajithkumar Sophiya , Sepehr Maleki , Giuseppe Bruni , Senthil K. Krishnababu

Physics-informed neural networks (PINNs), owing to their mesh-free nature, offer a powerful approach for solving high-dimensional partial differential equations (PDEs) in complex geometries, including irregular domains. This capability…

Numerical Analysis · Mathematics 2025-06-06 Hanfei Zhou , Lei Shi

Physics Informed Neural Networks is a numerical method which uses neural networks to approximate solutions of partial differential equations. It has received a lot of attention and is currently used in numerous physical and engineering…

Numerical Analysis · Mathematics 2025-07-10 Dimitrios Gazoulis , Ioannis Gkanis , Charalambos G. Makridakis