Related papers: The combinatorial code and the graph rules of Dale…
We examine a family of random firing-rate neural networks in which we enforce the neurobiological constraint of Dale's Law --- each neuron makes either excitatory or inhibitory connections onto its post-synaptic targets. We find that this…
We study a mathematical model of biological neuronal networks composed by any finite number $N \geq 2$ of non necessarily identical cells. The model is a deterministic dynamical system governed by finite-dimensional impulsive differential…
The construction of biologically plausible models of neural circuits is crucial for understanding the computational properties of the nervous system. Constructing functional networks composed of separate excitatory and inhibitory neurons…
The brain encodes spacial structure through a combinatorial code of neural activity. Experiments suggest such codes correspond to convex areas of the subject's environment. We present an intrinsic condition that implies a neural code may…
Networks of neurons in the brain encode preferred patterns of neural activity via their synaptic connections. Despite receiving considerable attention, the precise relationship between network connectivity and encoded patterns is still…
A combinatorial neural code is a subset of the power set $2^{[n]}$ on $[n]=\{1,\dots, n\}$, in which each $1\leq i\leq n$ represents a neuron and each element (codeword) represents the co-firing event of some neurons. Consider a space…
Dale's principle implies that biological neural networks are composed of neurons that are either excitatory or inhibitory. While the number of possible architectures of such Daleian networks is exponentially smaller than non-Daleian ones,…
Dale's Principle has historically guided neuroscience research as a valuable rule of thumb, namely that all synapses on each neuron release the same set of neurotransmitters. Most existing Spiking Neuron Network models share this…
This dissertation explores applications of discrete geometry in mathematical neuroscience. We begin with convex neural codes, which model the activity of hippocampal place cells and other neurons with convex receptive fields. In Chapter 4,…
In the study of randomly connected neural network dynamics there is a phase transition from a `simple' state with few equilibria to a `complex' state characterised by the number of equilibria growing exponentially with the neuron…
Neural codes allow the brain to represent, process, and store information about the world. Combinatorial codes, comprised of binary patterns of neural activity, encode information via the collective behavior of populations of neurons. A…
Neural network models in neuroscience allow one to study how the connections between neurons shape the activity of neural circuits in the brain. In this chapter, we study Combinatorial Threshold-Linear Networks (CTLNs) in order to…
This paper is concerned with the modeling and analysis of two of the most commonly used recurrent neural network models (i.e., Hopfield neural network and firing-rate neural network) with dynamic recurrent connections undergoing Hebbian…
Neural codes serve as a language for neurons in the brain. Convex codes, which arise from the pattern of intersections of convex sets in Euclidean space, are of particular relevance to neuroscience. Not every code is convex, however, and…
The power-law behavior is ubiquitous in a majority of real-world networks, and it was shown to have a strong effect on various combinatorial, structural, and dynamical properties of graphs. For example, it has been shown that in real-life…
In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…
To evaluate the nature of the neural code in the cerebral cortex, we have used a combination of theory and experiment to assess how information is represented in a realistic cortical population response. We have shown how a sensory stimulus…
Given two subsets A and B of nodes in a directed graph, the conduciveness of the graph from A to B is the ratio representing how many of the edges outgoing from nodes in A are incoming to nodes in B. When the graph's nodes stand for the…
The architecture of a neural network constrains the potential dynamics that can emerge. Some architectures may only allow for a single dynamic regime, while others display a great deal of flexibility with qualitatively different dynamics…
Convex neural codes are subsets of the Boolean lattice that record the intersection patterns of convex sets in Euclidean space. Much work in recent years has focused on finding combinatorial criteria on codes that can be used to classify…