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We investigate numerically how the motion of an intruder within a two-dimensional granular system affects its structure and produces drag on the intruder. We made use of discrete numerical simulations in which a larger disk (intruder) is…
Solids with spatial variations in the crystalline axes naturally evolve into cells or grains separated by sharp walls. Such variations are mathematically described using the Nye dislocation density tensor. At high temperatures,…
The wear-driven structural evolution of nanocrystalline Cu was simulated with molecular dynamics under constant normal loads, followed by a quantitative analysis. While the microstructure far away from the sliding contact remains unchanged,…
The formation and dynamics of a wide variety of binary two-dimensional ordered structures and superlattices are investigated through a phase field crystal model with sublattice ordering. Various types of binary ordered phases, the phase…
Cells in tissues can organize into a broad spectrum of structures according to their function. Drastic changes of organization, such as epithelial-mesenchymal transitions or the formation of spheroidal aggregates, are often associated…
Cells collectively migrate as a cluster in three-dimensional (3D) tissues, such as in embryogenesis and cancer invasion. Here, numerical simulations using a 3D vertex model show that polarized interfacial tension, expressing cell adhesion…
Twisted and rope-like assemblies of filamentous molecules are common and vital structural elements in cells and tissue of living organisms. We study the intrinsic frustration occurring in these materials between the two-dimensional…
During plastic deformation, metals change shape while continuously becoming stronger. The microscopic origin of these processes lies in the proliferation and movement of line defects, dislocations, and the subsequent self-organisation and…
Context: Sticking of colliding dust particles through van der Waals forces is the first stage in the grain growth process in protoplanetary disks, eventually leading to the formation of comets, asteroids and planets. A key aspect of the…
We study the crushing strength of brittle materials whose internal structure (e.g., mineral particles or graining) presents a layered arrangement reminiscent of sedimentary and metamorphic rocks. Taking a discrete-element approach, we probe…
We study the aging of colloidal gels using light microscopy movies of depletion gels from the International Space Station. Under such microgravity conditions, we observe a slowdown in particle dynamics consistent with gel aging. Stronger…
The effects of cell size and deformability on the lateral migration and deformation of living cells flowing through a rectangular microchannel has been numerically investigated and compared with the inertial-microfluidics data on detection…
Folding and aggregation of proteins, the interaction between proteins and membranes, as well as the adsorption of organic soft matter to inorganic solid substrates belong to the most interesting challenges in understanding structure and…
Collective migration dominates many phenomena, from cell movement in living systems to abiotic self-propelling particles. Focusing on the early stages of tumor evolution, we enunciate the principles involved in cell dynamics and highlight…
The emergence of macroscopic variables can be effected through {\it coarse graining}. Despite practical and fundamental benefits conveyed by this partitioning of state space, the apparently subjective nature of the selection of coarse…
In this work, a numerical simulation framework is presented based on the Phase Field Method that is able to capture the evolution of heterogeneous metallic microstructures during solidification. The involved physics can prove especially…
With a loose reference to problems of penetration in biomechanics (for instance, a nanoparticle penetrating through a cell's membrane or a cell sucked with a pipette), the role of configurational forces is investigated during the process in…
This study proposes a new analytical model for grain boundary pinning by second phase particles in two-dimensional polycrystals. This approach not only considers how particles impede grain growth, but also elucidates their role in…
Granular creep is the slow, sub-yield movement of constituents in a granular packing due to the disordered nature of its grain-scale interactions. Despite the ubiquity of creep in disordered materials, it is still not understood how to best…
Numerous experimental studies have demonstrated that the microenvironment is a key regulator influencing the proliferative and migrative potentials of species. Spatial and temporal disturbances lead to adverse and hazardous…