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Neuro-evolution and neural architecture search algorithms have gained increasing interest due to the challenges involved in designing optimal artificial neural networks (ANNs). While these algorithms have been shown to possess the potential…

Neural and Evolutionary Computing · Computer Science 2019-10-01 Travis J. Desell , AbdElRahman A. ElSaid , Alexander G. Ororbia

Survival analysis is essential for studying time-to-event outcomes and providing a dynamic understanding of the probability of an event occurring over time. Various survival analysis techniques, from traditional statistical models to…

Machine Learning · Computer Science 2024-03-13 Ziwen Wang , Jin Wee Lee , Tanujit Chakraborty , Yilin Ning , Mingxuan Liu , Feng Xie , Marcus Eng Hock Ong , Nan Liu

Kernel-based multi-marker tests for survival outcomes use primarily the Cox model to adjust for covariates. The proportional hazards assumption made by the Cox model could be unrealistic, especially in the long-term follow-up. We develop a…

Methodology · Statistics 2024-01-19 Chenxi Li , Di Wu , Qing Lu

Causal structure discovery in complex dynamical systems is an important challenge for many scientific domains. Although data from (interventional) experiments is usually limited, large amounts of observational time series data sets are…

Machine Learning · Computer Science 2021-10-19 Bart Bussmann , Jannes Nys , Steven Latré

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Deep neural networks (DNNs) have become powerful tools for modeling complex data structures through sequentially integrating simple functions in each hidden layer. In survival analysis, recent advances of DNNs primarily focus on enhancing…

Machine Learning · Statistics 2025-03-26 Changhui Yuan , Shishun Zhao , Shuwei Li , Xinyuan Song , Zhao Chen

This work considers the trade-off between accuracy and test-time computational cost of deep neural networks (DNNs) via \emph{anytime} predictions from auxiliary predictions. Specifically, we optimize auxiliary losses jointly in an…

Machine Learning · Computer Science 2018-05-28 Hanzhang Hu , Debadeepta Dey , Martial Hebert , J. Andrew Bagnell

Hardware-aware Neural Architecture Search (NAS) is one of the most promising techniques for designing efficient Deep Neural Networks (DNNs) for resource-constrained devices. Surrogate models play a crucial role in hardware-aware NAS as they…

Machine Learning · Computer Science 2025-08-05 Azaz-Ur-Rehman Nasir , Samroz Ahmad Shoaib , Muhammad Abdullah Hanif , Muhammad Shafique

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Deep neural networks (DNNs) have proven to be highly effective in a variety of tasks, making them the go-to method for problems requiring high-level predictive power. Despite this success, the inner workings of DNNs are often not…

Machine Learning · Statistics 2024-03-04 Anton Thielmann , René-Marcel Kruse , Thomas Kneib , Benjamin Säfken

Turbofan engine degradation under sustained operational stress necessitates robust prognostic systems capable of accurately estimating the Remaining Useful Life (RUL) of critical components. Existing deep learning approaches frequently fail…

Machine Learning · Computer Science 2026-04-21 Mohammed Ezzaldin Babiker Abdullah

Observational longitudinal data on treatments and covariates are increasingly used to investigate treatment effects, but are often subject to time-dependent confounding. Marginal structural models (MSMs), estimated using inverse probability…

Methodology · Statistics 2020-02-11 Ruth H. Keogh , Shaun R. Seaman , Jon Michael Gran , Stijn Vansteelandt

Concept-based learning enhances prediction accuracy and interpretability by leveraging high-level, human-understandable concepts. However, existing CBL frameworks do not address survival analysis tasks, which involve predicting event times…

Machine Learning · Computer Science 2025-02-11 Stanislav R. Kirpichenko , Lev V. Utkin , Andrei V. Konstantinov , Natalya M. Verbova

Automated machine learning (AutoML) has seen a resurgence in interest with the boom of deep learning over the past decade. In particular, Neural Architecture Search (NAS) has seen significant attention throughout the AutoML research…

Neural and Evolutionary Computing · Computer Science 2020-09-23 Min Shi , David A. Wilson , Xingquan Zhu , Yu Huang , Yuan Zhuang , Jianxun Liu , Yufei Tang

Cox-nnet is a neural-network based prognosis prediction method, originally applied to genomics data. Here we propose the version 2 of Cox-nnet, with significant improvement on efficiency and interpretability, making it suitable to predict…

Quantitative Methods · Quantitative Biology 2020-09-10 Di Wang , Kevin He , Lana X Garmire

We present a machine learning framework capable of consistently inferring mathematical expressions of hyperelastic energy functionals for incompressible materials from sparse experimental data and physical laws. To achieve this goal, we…

Computational Engineering, Finance, and Science · Computer Science 2024-02-13 Bahador Bahmani , WaiChing Sun

We propose a novel method for predicting time-to-event in the presence of cure fractions based on flexible survivals models integrated into a deep neural network framework. Our approach allows for non-linear relationships and…

Machine Learning · Statistics 2024-11-11 Victor Medina-Olivares , Stefan Lessmann , Nadja Klein

Identification of biomarkers is an emerging area in Oncology. In this article, we develop an efficient statistical procedure for classification of protein markers according to their effect on cancer progression. A high-dimensional…

Applications · Statistics 2021-01-08 Souvik Banerjee , Gajendra K. Vishwakarma , Atanu Bhattacharjee

We consider a joint survival and mixed-effects model to explain the survival time from longitudinal data and high-dimensional covariates in a population. The longitudinal data is modeled using a non linear mixed-effects model to account for…

Statistics Theory · Mathematics 2025-08-06 Antoine Caillebotte , Estelle Kuhn , Sarah Lemler