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Neural Architecture Search (NAS) is an important yet challenging task in network design due to its high computational consumption. To address this issue, we propose the Reinforced Evolutionary Neural Architecture Search (RE- NAS), which is…

Neural and Evolutionary Computing · Computer Science 2019-04-11 Yukang Chen , Gaofeng Meng , Qian Zhang , Shiming Xiang , Chang Huang , Lisen Mu , Xinggang Wang

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Survival models are a popular tool for the analysis of time to event data with applications in medicine, engineering, economics, and many more. Advances like the Cox proportional hazard model have enabled researchers to better describe…

Machine Learning · Statistics 2021-02-16 Stefan Groha , Sebastian M Schmon , Alexander Gusev

This paper proposes a method for lifelong learning of Recurrent Neural Networks, such as NNARX, ESN, LSTM, and GRU, to be used as plant models in control system synthesis. The problem is significant because in many practical applications it…

Systems and Control · Electrical Eng. & Systems 2022-08-09 Fabio Bonassi , Jing Xie , Marcello Farina , Riccardo Scattolini

Although the Cox proportional hazards model is well established and extensively used in the analysis of survival data, the proportional hazards (PH) assumption may not always hold in practical scenarios. The class of semiparametric…

Methodology · Statistics 2025-10-21 Junkai Yin , Yue Zhang , Zhangsheng Yu

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Autoregressive (AR) models remain widely used in time series analysis due to their interpretability, but convencional parameter estimation methods can be computationally expensive and prone to convergence issues. This paper proposes a…

Machine Learning · Statistics 2026-03-20 Anaísa Lucena , Ana Martins , Armando J. Pinho , Sónia Gouveia

Intelligibility and accurate uncertainty estimation are crucial for reliable decision-making. In this paper, we propose EviNAM, an extension of evidential learning that integrates the interpretability of Neural Additive Models (NAMs) with…

Machine Learning · Computer Science 2026-01-14 Sören Schleibaum , Anton Frederik Thielmann , Julian Teusch , Benjamin Säfken , Jörg P. Müller

Purpose: Automated medical image-based prediction of clinical outcomes, such as overall survival (OS), has great potential in improving patient prognostics and personalized treatment planning. We developed a deep regression framework using…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Sambit Tarai , Ashish Chauhan , Elin Lundström , Johan Öfverstedt , Therese Sjöholm , Veronica Sanchez Rodriguez , Håkan Ahlström , Joel Kullberg

Survival analysis is an important research topic with applications in healthcare, business, and manufacturing. One essential tool in this area is the Cox proportional hazards (CPH) model, which is widely used for its interpretability,…

Machine Learning · Computer Science 2024-10-28 Jiachang Liu , Rui Zhang , Cynthia Rudin

In the absence of data from a randomized trial, researchers often aim to use observational data to draw causal inference about the effect of a treatment on a time-to-event outcome. In this context, interest often focuses on the…

Methodology · Statistics 2021-06-15 Ted Westling , Alex Luedtke , Peter Gilbert , Marco Carone

This paper establishes a series of sensitivity analyses to investigate the impact of missing values in the electronic health records (EHR) that are possibly missing not at random (MNAR). EHRs have gained tremendous interest due to their…

Methodology · Statistics 2025-03-28 Jungwun Lee , Sebastien Haneuse , Rajarshi Mukherjee , Tanayott Thaweethai

Electronic health records (EHRs) contain structured and unstructured data of significant clinical and research value. Various machine learning approaches have been developed to employ information in EHRs for risk prediction. The majority of…

In breast cancer, neoadjuvant chemotherapy (NAC) provides a standard treatment option for patients who have locally advanced cancer and some large operable tumors. A patient will have better prognosis when he has achieved a pathological…

Medical Physics · Physics 2024-11-12 Yongquan Yang , Fengling Li , Yani Wei , Yuanyuan Zhao , Jing Fu , Xiuli Xiao , Hong Bu

One of the central goals in precision health is the understanding and interpretation of high-dimensional biological data to identify genes and markers associated with disease initiation, development, and outcomes. Though significant effort…

Quantitative Methods · Quantitative Biology 2020-09-18 Zhi Huang , Paul Salama , Wei Shao , Jie Zhang , Kun Huang

Motivation: Electronic Health Records (EHR) represent a comprehensive resource of a patient's medical history. EHR are essential for utilizing advanced technologies such as deep learning (DL), enabling healthcare providers to analyze…

Machine Learning · Computer Science 2024-07-24 Mohammad Al Olaimat , Serdar Bozdag

An individualized risk prediction model that dynamically updates the probability of a clinical event from a specific cause is valuable for physicians to be able to optimize personalized treatment strategies in real-time by incorporating all…

Methodology · Statistics 2019-04-22 Qing Liu , Gong Tang , Joseph P. Costantino , Chung-Chou H. Chang

Survival analysis (SA) models have been widely studied in mining electronic health records (EHRs), particularly in forecasting the risk of critical conditions for prioritizing high-risk patients. However, their vulnerability to adversarial…

Machine Learning · Computer Science 2024-12-30 Mohsen Nayebi Kerdabadi , Arya Hadizadeh Moghaddam , Bin Liu , Mei Liu , Zijun Yao