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We describe the design, implementation and performance of the RADICAL-Pilot task overlay (RAPTOR). RAPTOR enables the execution of heterogeneous tasks -- i.e., functions and executables with arbitrary duration -- on HPC platforms, providing…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-02 Andre Merzky , Matteo Turilli , Shantenu Jha

Nanopore sequencing technology has the potential to render other sequencing technologies obsolete with its ability to generate long reads and provide portability. However, high error rates of the technology pose a challenge while generating…

Genomics · Quantitative Biology 2019-12-20 Damla Senol Cali , Jeremie S. Kim , Saugata Ghose , Can Alkan , Onur Mutlu

A critical step of genome sequence analysis is the mapping of sequenced DNA fragments (i.e., reads) collected from an individual to a known linear reference genome sequence (i.e., sequence-to-sequence mapping). Recent works replace the…

Continual learning on edge platforms remains challenging because recurrent networks depend on energy-intensive training procedures and frequent data movement that are impractical for embedded deployments. This work introduces M2RU, a…

Machine Learning · Computer Science 2025-12-29 Abdullah M. Zyarah , Dhireesha Kudithipudi

Nowadays a diverse range of physiological data can be captured continuously for various applications in particular wellbeing and healthcare. Such data require efficient methods for classification and analysis. Deep learning algorithms have…

Machine Learning · Computer Science 2018-11-02 Hamid Soleimani , Aliasghar , Makhlooghpour , Wilten Nicola , Claudia Clopath , Emmanuel. M. Drakakis

Advances in third-generation sequencing have enabled portable and real-time genomic sequencing, but real-time data processing remains a bottleneck, hampering on-site genomic analysis due to prohibitive time and energy costs. These…

Emerging Technologies · Computer Science 2025-04-23 Peiyi He , Shengbo Wang , Ruibin Mao , Sebastian Siegel , Giacomo Pedretti , Jim Ignowski , John Paul Strachan , Ruibang Luo , Can Li

The steeply growing performance demands for highly power- and energy-constrained processing systems such as end-nodes of the internet-of-things (IoT) have led to parallel near-threshold computing (NTC), joining the energy-efficiency…

Hardware Architecture · Computer Science 2020-04-15 Florian Glaser , Giuseppe Tagliavini , Davide Rossi , Germain Haugou , Qiuting Huang , Luca Benini

One of the main limitations of utilizing optimal wavefront shaping in imaging and authentication applications is the slow speed of the optimization algorithms currently being used. To address this problem we develop a micro-genetic…

Motivation: High throughput DNA sequencing (HTS) technologies generate an excessive number of small DNA segments -- called short reads -- that cause significant computational burden. To analyze the entire genome, each of the billions of…

Genomics · Quantitative Biology 2020-09-29 Mohammed Alser , Hasan Hassan , Hongyi Xin , Oğuz Ergin , Onur Mutlu , Can Alkan

As spiking-based deep learning inference applications are increasing in embedded systems, these systems tend to integrate neuromorphic accelerators such as $\mu$Brain to improve energy efficiency. We propose a $\mu$Brain-based scalable…

Neural and Evolutionary Computing · Computer Science 2021-11-24 M. Lakshmi Varshika , Adarsha Balaji , Federico Corradi , Anup Das , Jan Stuijt , Francky Catthoor

Deploying deep neural networks (DNNs) across homogeneous edge devices (the devices with the same SKU labeled by the manufacturer) often assumes identical performance among them. However, once a device model is widely deployed, the…

Machine Learning · Computer Science 2025-12-23 Kunlong Zhang , Guiying Li , Ning Lu , Peng Yang , Ke Tang

Energy harvesting (EH) IoT devices that operate intermittently without batteries, coupled with advances in deep neural networks (DNNs), have opened up new opportunities for enabling sustainable smart applications. Nevertheless, implementing…

Machine Learning · Computer Science 2022-07-07 Sahidul Islam , Jieren Deng , Shanglin Zhou , Chen Pan , Caiwen Ding , Mimi Xie

Hardware failures are a growing challenge for machine learning accelerators, many of which are based on systolic arrays. When a permanent hardware failure occurs in a systolic array, existing solutions include localizing and isolating the…

Machine Learning · Computer Science 2024-12-24 Youssef A. Ait Alama , Sampada Sakpal , Ke Wang , Razvan Bunescu , Avinash Karanth , Ahmed Louri

Structural pruning can simplify network architecture and improve inference speed. We propose Hardware-Aware Latency Pruning (HALP) that formulates structural pruning as a global resource allocation optimization problem, aiming at maximizing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Maying Shen , Hongxu Yin , Pavlo Molchanov , Lei Mao , Jianna Liu , Jose M. Alvarez

Traditional learning-based approaches for run-time Hardware Trojan detection require complex and expensive on-chip data acquisition frameworks and thus incur high area and power overhead. To address these challenges, we propose to leverage…

Cryptography and Security · Computer Science 2020-11-25 Faiq Khalid , Syed Rafay Hasan , Sara Zia , Osman Hasan , Falah Awwad , Muhammad Shafique

Innovations in Next-Generation Sequencing are enabling generation of DNA sequence data at ever faster rates and at very low cost. Large sequencing centers typically employ hundreds of such systems. Such high-throughput and low-cost…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-31 Vasimuddin Md , Sanchit Misra , Heng Li , Srinivas Aluru

Genome analysis has revolutionized fields such as personalized medicine and forensics. Modern sequencing machines generate vast amounts of fragmented strings of genome data called reads. The alignment of these reads into a complete DNA…

Hardware Architecture · Computer Science 2024-11-22 Rotem Ben-Hur , Orian Leitersdorf , Ronny Ronen , Lidor Goldshmidt , Idan Magram , Lior Kaplun , Leonid Yavitz , Shahar Kvatinsky

Deploying deep neural networks (DNNs) across homogeneous edge devices (the devices with the same SKU labeled by the manufacturer) often assumes identical performance among them. However, once a device model is widely deployed, the…

Hardware Architecture · Computer Science 2025-12-16 Kunlong Zhang , Guiying Li , Ning Lu , Peng Yang , Ke Tang

Modern applications can generate a large amount of data from different sources with high velocity, a combination that is difficult to store and process via traditional tools. Hadoop is one framework that is used for the parallel processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-29 Rana Ghazali , Sahar Adabi , Ali Rezaee , Douglas G. Down , Ali Movaghar

As process technology continues to scale aggressively, circuit aging in a neuromorphic hardware due to negative bias temperature instability (NBTI) and time-dependent dielectric breakdown (TDDB) is becoming a critical reliability issue and…

Neural and Evolutionary Computing · Computer Science 2020-06-11 Shihao Song , Anup Das , Nagarajan Kandasamy
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