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Related papers: MixUp-MIL: Novel Data Augmentation for Multiple In…

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Multiple Instance Learning (MIL) has been widely applied in pathology towards solving critical problems such as automating cancer diagnosis and grading, predicting patient prognosis, and therapy response. Deploying these models in a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Syed Ashar Javed , Dinkar Juyal , Harshith Padigela , Amaro Taylor-Weiner , Limin Yu , Aaditya Prakash

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Mixup refers to interpolation-based data augmentation, originally motivated as a way to go beyond empirical risk minimization (ERM). Its extensions mostly focus on the definition of interpolation and the space (input or feature) where it…

Machine Learning · Computer Science 2023-11-10 Shashanka Venkataramanan , Ewa Kijak , Laurent Amsaleg , Yannis Avrithis

Class-Incremental learning (CIL) refers to the ability of artificial agents to integrate new classes as they appear in a stream. It is particularly interesting in evolving environments where agents have limited access to memory and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Eden Belouadah , Arnaud Dapogny , Kevin Bailly

In recent years, a standard computational pathology workflow has emerged where whole slide images are cropped into tiles, these tiles are processed using a foundation model, and task-specific models are built using the resulting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Eric Zimmermann , Julian Viret , Michal Zelechowski , James Brian Hall , Neil Tenenholtz , Adam Casson , George Shaikovski , Eugene Vorontsov , Siqi Liu , Kristen A Severson

Mixup-based augmentation has been found to be effective for generalizing models during training, especially for Vision Transformers (ViTs) since they can easily overfit. However, previous mixup-based methods have an underlying prior…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Jie-Neng Chen , Shuyang Sun , Ju He , Philip Torr , Alan Yuille , Song Bai

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Multiple instance learning (MIL) was a weakly supervised learning approach that sought to assign binary class labels to collections of instances known as bags. However, due to their weak supervision nature, the MIL methods were susceptible…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Oana M. Dumitrascu , Yalin Wang

Data augmentation is a common practice to help generalization in the procedure of deep model training. In the context of physiological time series classification, previous research has primarily focused on label-invariant data augmentation…

Machine Learning · Computer Science 2023-09-19 Peikun Guo , Huiyuan Yang , Akane Sano

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

The differentiation between tumor recurrence and radiation-induced contrast enhancements in post-treatment glioblastoma patients remains a major clinical challenge. Existing approaches rely on clinically sparsely available diffusion MRI or…

Many medical datasets have recently been created for medical image segmentation tasks, and it is natural to question whether we can use them to sequentially train a single model that (1) performs better on all these datasets, and (2)…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Chenyu You , Jinlin Xiang , Kun Su , Xiaoran Zhang , Siyuan Dong , John Onofrey , Lawrence Staib , James S. Duncan

Multi-Instance Learning(MIL) aims to learn the mapping between a bag of instances and the bag-level label. Therefore, the relationships among instances are very important for learning the mapping. In this paper, we propose an MIL algorithm…

Machine Learning · Computer Science 2021-02-04 Yangling Ma , Zhouwang Yang

Multiple-instance Learning (MIL) is commonly used to undertake computational pathology (CPath) tasks, and the use of multi-scale patches allows diverse features across scales to be learned. Previous studies using multi-scale features in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A Fallowfield , Hakan Bilen , Timothy J Kendall

Due to the significant effort required for data collection and annotation in 3D perception tasks, mixed sample data augmentation (MSDA) has been widely studied to generate diverse training samples by mixing existing data. Recently, many…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Miao Zhang , Sherif Abdulatif , Benedikt Loesch , Marco Altmann , Bin Yang

Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…

Image and Video Processing · Electrical Eng. & Systems 2026-05-08 Tianyi Zhang , Sicheng Chen , Borui Kang , Dankai Liao , Qiaochu Xue , Bochong Zhang , Fei Xia , Zeyu Liu , Yueming Jin

Accurate and robust medical image classification is a challenging task, especially in application domains where available annotated datasets are small and present high imbalance between target classes. Considering that data acquisition is…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Neil De La Fuente , Mireia Majó , Irina Luzko , Henry Córdova , Gloria Fernández-Esparrach , Jorge Bernal

Multiple instance learning (MIL) is the dominant framework for whole-slide image analysis in computational pathology, typically combining a frozen patch encoder, a projection layer, and a slide-level aggregator. While encoders and…

Quantitative Methods · Quantitative Biology 2026-05-19 Yucheng Xing , Pei Liu , Jingying Ma , Ruping Hong , Jiangdong Qiu , Tianyu Liu , Kai He , Ling Huang , Mengling Feng

Mixup is a widely adopted strategy for training deep networks, where additional samples are augmented by interpolating inputs and labels of training pairs. Mixup has shown to improve classification performance, network calibration, and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Thomas Mensink , Pascal Mettes

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu