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It is difficult to accurately label ambiguous and complex shaped targets manually by binary masks. The weakness of binary mask under-expression is highlighted in medical image segmentation, where blurring is prevalent. In the case of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Lin Wang , Lie Ju , Xin Wang , Wanji He , Donghao Zhang , Yelin Huang , Zhiwen Yang , Xuan Yao , Xin Zhao , Xiufen Ye , Zongyuan Ge

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

Medical image segmentation aims to identify anatomical structures at the voxel-level. Segmentation accuracy relies on distinguishing voxel differences. Compared to advancements achieved in studies of the inter-class variance, the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Yali Bi , Enyu Che , Yinan Chen , Yuanpeng He , Jingwei Qu

Lesion-symptom mapping studies provide insight into what areas of the brain are involved in different aspects of cognition. This is commonly done via behavioral testing in patients with a naturally occurring brain injury or lesions (e.g.,…

The development of accurate methods for multi-label classification (MLC) of remote sensing (RS) images is one of the most important research topics in RS. The MLC methods based on convolutional neural networks (CNNs) have shown strong…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Ahmet Kerem Aksoy , Mahdyar Ravanbakhsh , Begüm Demir

Lesion detection is an important problem within medical imaging analysis. Most previous work focuses on detecting and segmenting a specialized category of lesions (e.g., lung nodules). However, in clinical practice, radiologists are…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Ke Yan , Jinzheng Cai , Adam P. Harrison , Dakai Jin , Jing Xiao , Le Lu

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-07 Mehdi SadeghiBakhi , Hamidreza Pourreza , Hamidreza Mahyar

Segmentation and quantification of white matter hyperintensities (WMHs) are of great importance in studying and understanding various neurological and geriatric disorders. Although automatic methods have been proposed for WMH segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-03-20 Dakai Jin , Ziyue Xu , Adam P. Harrison , Daniel J. Mollura

Despite the state-of-the-art performance for medical image segmentation, deep convolutional neural networks (CNNs) have rarely provided uncertainty estimations regarding their segmentation outputs, e.g., model (epistemic) and image-based…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Guotai Wang , Wenqi Li , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

Machine learning algorithms underpin modern diagnostic-aiding software, which has proved valuable in clinical practice, particularly in radiology. However, inaccuracies, mainly due to the limited availability of clinical samples for…

The consideration of predictive uncertainty in medical imaging with deep learning is of utmost importance. We apply estimation of both aleatoric and epistemic uncertainty by variational Bayesian inference with Monte Carlo dropout to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-27 Max-Heinrich Laves , Sontje Ihler , Jacob F. Fast , Lüder A. Kahrs , Tobias Ortmaier

Many current state-of-the-art methods for anomaly localization in medical images rely on calculating a residual image between a potentially anomalous input image and its "healthy" reconstruction. As the reconstruction of the unseen…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Benedikt Wiestler , Georgios Kaissis , Daniel Rueckert

Background: Accurate lesion segmentation is critical for multiple sclerosis (MS) diagnosis, yet current deep learning approaches face robustness challenges. Aim: This study improves MS lesion segmentation by combining data fusion and deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-18 Nadezhda Alsahanova , Pavel Bartenev , Maksim Sharaev , Milos Ljubisavljevic , Taleb Al. Mansoori , Yauhen Statsenko

In multiple sclerosis, lesions interfere with automated magnetic resonance imaging analyses such as brain parcellation and deformable registration, while lesion segmentation models are hindered by the limited availability of annotated…

Large language models (LLMs) often generate fluent but factually incorrect outputs, known as hallucinations, which undermine their reliability in real-world applications. While uncertainty estimation has emerged as a promising strategy for…

Machine Learning · Computer Science 2025-05-13 Pei-Fu Guo , Yun-Da Tsai , Shou-De Lin

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

In this paper, we develop a two-stage neural network solution for the challenging task of white-matter lesion segmentation. To cope with the vast vari- ability in lesion sizes, we sample brain MR scans with patches at three differ- ent…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Zhewei Wang , Charles D. Smith , Jundong Liu

Semi-supervised learning in medical image segmentation leverages unlabeled data to reduce annotation burdens through consistency learning. However, current methods struggle with class imbalance and high uncertainty from pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Maregu Assefa , Muzammal Naseer , Iyyakutti Iyappan Ganapathi , Syed Sadaf Ali , Mohamed L Seghier , Naoufel Werghi

The damage detection problem in mechanical systems, using vibration measurements, is commonly called Structural Health Monitoring (SHM). Many tools are able to detect damages by changes in the vibration pattern, mainly, when damages induce…

Computational Engineering, Finance, and Science · Computer Science 2024-09-25 Luis Gustavo Giacon Villani , Samuel da Silva , Americo Cunha