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Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

Image-based precision medicine aims to personalize treatment decisions based on an individual's unique imaging features so as to improve their clinical outcome. Machine learning frameworks that integrate uncertainty estimation as part of…

Machine Learning · Computer Science 2023-08-11 Joshua Durso-Finley , Jean-Pierre Falet , Raghav Mehta , Douglas L. Arnold , Nick Pawlowski , Tal Arbel

Deep neural networks are known to be data-driven and label noise can have a marked impact on model performance. Recent studies have shown great robustness to classic image recognition even under a high noisy rate. In medical applications,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-23 Lie Ju , Xin Wang , Lin Wang , Dwarikanath Mahapatra , Xin Zhao , Mehrtash Harandi , Tom Drummond , Tongliang Liu , Zongyuan Ge

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Ashiqur Rahman , Muhammad E. H. Chowdhury , Md Sharjis Ibne Wadud , Rusab Sarmun , Adam Mushtak , Sohaib Bassam Zoghoul , Israa Al-Hashimi

Self-paced curriculum learning (SCL) has demonstrated its great potential in computer vision, natural language processing, etc. During training, it implements easy-to-hard sampling based on online estimation of data difficulty. Most SCL…

Computer Vision and Pattern Recognition · Computer Science 2023-02-10 Han Li , Hu Han , S. Kevin Zhou

In recent years, multi-view multi-label learning (MVML) has gained popularity due to its close resemblance to real-world scenarios. However, the challenge of selecting informative features to ensure both performance and efficiency remains a…

Machine Learning · Computer Science 2025-03-19 Pingting Hao , Kunpeng Liu , Wanfu Gao

We propose a unified objective function, termed CATMIL, that augments the base segmentation loss with two auxiliary supervision terms operating at different levels. The first term, Component-Adaptive Tversky, reweights voxel contributions…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Minh Sao Khue Luu , Evgeniy N. Pavlovskiy , Bair N. Tuchinov

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies

Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Saket Maganti

Neural demyelination and brain damage accumulated in white matter appear as hyperintense areas on T2-weighted MRI scans in the form of lesions. Modeling binary images at the population level, where each voxel represents the existence of a…

Methodology · Statistics 2023-05-29 Anna Menacher , Thomas E. Nichols , Chris Holmes , Habib Ganjgahi

Deep learning techniques show success in detecting objects in medical images, but still suffer from false-positive predictions that may hinder accurate diagnosis. The estimated uncertainty of the neural network output has been used to flag…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Ishaan Bhat , Josien P. W. Pluim , Max A. Viergever , Hugo J. Kuijf

Acute stroke lesion segmentation tasks are of great clinical interest as they can help doctors make better informed treatment decisions. Magnetic resonance imaging (MRI) is time demanding but can provide images that are considered gold…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Albert Clèrigues , Sergi Valverde , Jose Bernal , Jordi Freixenet , Arnau Oliver , Xavier Lladó

Accurate lesion segmentation is crucial for clinical diagnosis and treatment planning. However, lesions often resemble surrounding tissues and exhibit ill-defined boundaries, leading to unstable predictions in boundary/transition regions.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Shuokun Cheng , Jinghao Shi , Kun Sun

This paper investigates methods for estimating uncertainty in semantic segmentation predictions derived from satellite imagery. Estimating uncertainty for segmentation presents unique challenges compared to standard image classification,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Melanie Rey , Andriy Mnih , Maxim Neumann , Matt Overlan , Drew Purves

Effective and rapid detection of lesions in the Gastrointestinal tract is critical to gastroenterologist's response to some life-threatening diseases. Wireless Capsule Endoscopy (WCE) has revolutionized traditional endoscopy procedure by…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Sodiq Adewole , Philip Fernandez , Michelle Yeghyayan , James Jablonski , Andrew Copland , Michael Porter , Sana Syed , Donald Brown

Average calibration of the (variance-based) prediction uncertainties of machine learning regression tasks can be tested in two ways: one is to estimate the calibration error (CE) as the difference between the mean absolute error (MSE) and…

Machine Learning · Statistics 2024-08-20 Pascal Pernot

In medical imaging, inter-observer variability among radiologists often introduces label uncertainty, particularly in modalities where visual interpretation is subjective. Lung ultrasound (LUS) is a prime example-it frequently presents a…