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This paper describes a technique for analyzing the stochastic structure of the vectorial capacity using moment--generating functions. In such formulation, for an infectious disease transmitted by a vector, we obtain the generating function…

Populations and Evolution · Quantitative Biology 2015-04-29 Daniel A. M. Villela

Horizontal gene transfer consists in exchanging genetic materials between microorganisms during their lives. This is a major mechanism of bacterial evolution and is believed to be of main importance in antibiotics resistance. We consider a…

Probability · Mathematics 2019-12-18 Nicolas Champagnat , Sylvie Méléard , Viet Chi Tran

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

Populations and Evolution · Quantitative Biology 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

Dynamical Systems · Mathematics 2025-10-03 Abdallah Alsammani

The purpose of this paper is to analyze the mechanism for the interplay of deterministic and stochastic models for contagious diseases. Deterministic models for contagious diseases are prone to predict global stability. Small natural birth…

Populations and Evolution · Quantitative Biology 2022-06-17 Torsten Lindström

Biological processes at the cellular level are stochastic in nature, and the immune response system is no different. Therefore, models that attempt to explain this system need to also incorporate noise or fluctuations that can account for…

Molecular Networks · Quantitative Biology 2021-06-16 Abhilasha Batra , Rati Sharma

We investigate a time-dependent spatial vector-host epidemic model with non-coincident domains for the vector and host populations. The host population resides in small non-overlapping sub-regions, while the vector population resides…

Analysis of PDEs · Mathematics 2018-09-12 W. E. Fitzgibbon , J. J. Morgan , Glenn F. Webb , Yixiang Wu

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

This paper presents a stochastic model motivated by the study of a virus-like evolving population with different mutation rates. This is a continuous time birth-death model: the birth processes are mutually-exciting Hawkes processes and the…

Probability · Mathematics 2026-03-10 Rahul Roy , Dharmaraja Selvamuthu , Paola Tardelli

Stochastic models of diffusion with excluded-volume effects are used to model many biological and physical systems at a discrete level. The average properties of the population may be described by a continuum model based on partial…

Chemical Physics · Physics 2012-12-20 Maria Bruna , S. Jonathan Chapman

Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

Applications · Statistics 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

Since the last century, deterministic compartmental models have emerged as powerful tools to predict and control epidemic outbreaks, in many cases helping to mitigate their impacts. A key quantity for these models is the so-called Basic…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Rosa Flaquer-Galmés , Manuel A. Matias

We propose a new stochastic epidemiological model defined in a continuous space of arbitrary dimension, based on SIS dynamics implemented in a spatial $\Lambda$-Fleming-Viot (SLFV) process. The model can be described by as little as three…

Probability · Mathematics 2026-01-09 Apolline Louvet , Bastian Wiederhold

We present an epidemiological model for vector-borne diseases that includes within-host viral load and antibody dynamics using structured transport equations. By incorporating the internal dynamics into the infected and recovered host…

Analysis of PDEs · Mathematics 2026-05-26 Paulo Amorim , Maria Soledad Aronna , Debora de Oliveira Medeiros

In the infectious disease literature, significant effort has been devoted to studying dynamics at a single scale. For example, compartmental models describing population-level dynamics are often formulated using differential equations. In…

Populations and Evolution · Quantitative Biology 2025-04-16 Yuan Yin , Jennifer A. Flegg , Mark B. Flegg

Modelling the transmission dynamics of an infectious disease is a complex task. Not only it is difficult to accurately model the inherent non-stationarity and heterogeneity of transmission, but it is nearly impossible to describe,…

Computation · Statistics 2023-07-19 Sanmitra Ghosh , Paul J. Birrell , Daniela De Angelis

Frequency dependent selection and demographic fluctuations play important roles in evolutionary and ecological processes. Under frequency dependent selection, the average fitness of the population may increase or decrease based on…

Populations and Evolution · Quantitative Biology 2015-06-23 Weini Huang , Christoph Hauert , Arne Traulsen

Vector-borne diseases arise from the coupled dynamics of human mobility and mosquito ecology, producing outbreaks shaped by both spatial distributions and temporal patterns of movement. Here we develop a coarse-grained hub--leaf reduction…

Populations and Evolution · Quantitative Biology 2025-08-29 Bibandhan Poudyal , Gourab Ghoshal

It is well-established that including spatial structure and stochastic noise in models for predator-prey interactions invalidates the classical deterministic Lotka-Volterra picture of neutral population cycles. In contrast, stochastic…

Populations and Evolution · Quantitative Biology 2011-09-20 Uwe C. Tauber

We develop a new structured compartmental model for the coevolutionary dynamics between susceptible and infectious individuals in heterogeneous SI epidemiological systems. In this model, the susceptible compartment is structured by a…

Populations and Evolution · Quantitative Biology 2024-10-10 Tommaso Lorenzi , Elisa Paparelli , Andrea Tosin