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Calcification has significant influence over cardiovascular diseases and interventions. Detailed characterization of calcification is thus desired for predictive modeling, but calcified heart meshes for physics-driven simulations are still…

Computational Engineering, Finance, and Science · Computer Science 2024-03-11 Daniel H. Pak , Minliang Liu , Theodore Kim , Caglar Ozturk , Raymond McKay , Ellen T. Roche , Rudolph Gleason , James S. Duncan

Effective preoperative planning requires accurate algorithms for segmenting anatomical structures across diverse datasets, but traditional models struggle with generalization. This study presents a novel machine learning methodology to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Mustafa Khanbhai , Giulia Di Nardo , Jun Ma , Vivienne Freitas , Caterina Masino , Ali Dolatabadi , Zhaoxun "Lorenz" Liu , Wey Leong , Wagner H. Souza , Amin Madani

Principal components analysis (PCA) is a well-known technique for approximating a tabular data set by a low rank matrix. Here, we extend the idea of PCA to handle arbitrary data sets consisting of numerical, Boolean, categorical, ordinal,…

Machine Learning · Statistics 2015-05-06 Madeleine Udell , Corinne Horn , Reza Zadeh , Stephen Boyd

We present a method using principal component analysis (PCA) to process x-ray pulses with severe shape variation where traditional optimal filter methods fail. We demonstrate that PCA is able to noise-filter and extract energy information…

Instrumentation and Detectors · Physics 2016-03-23 Daikang Yan , Thomas Cecil , Lisa Gades , Chris Jacobsen , Timothy Madden , Antonino Miceli

Principal component analysis (PCA) is a widely used method for data processing, such as for dimension reduction and visualization. Standard PCA is known to be sensitive to outliers, and thus, various robust PCA methods have been proposed.…

Machine Learning · Statistics 2020-08-11 Keishi Sando , Hideitsu Hino

Central venous catheters (CVC) are commonly inserted into the large veins of the neck, e.g. the internal jugular vein (IJV). CVC insertion may cause serious complications like misplacement into an artery or perforation of cervical vessels.…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Christian Schmidt , Heinrich Martin Overhoff

The Monte Carlo simulation of the dynamics of complex molecules produces trajectories with a large number of different configurations to sample configuration space. It is expected that these configurations can be classified into a small…

Computational Physics · Physics 2007-05-23 Christoph Best , Hans-Christian Hege

Early detection and analysis of calcifications in mammogram images is crucial in a breast cancer diagnosis workflow. Management of calcifications that require immediate follow-up and further analyzing its benignancy or malignancy can result…

Image and Video Processing · Electrical Eng. & Systems 2022-12-12 Adarsh Bhandary Panambur , Prathmesh Madhu , Andreas Maier

Principal Component Analysis (PCA) is known to be the most widely applied dimensionality reduction approach. A lot of improvements have been done on the traditional PCA, in order to obtain optimal results in the dimensionality reduction of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Chisom Ezinne Ogbuanya

Brillouin microscopy has recently emerged as a new bio-imaging modality that provides information on the micromechanical properties of biological materials, cells and tissues. The data collected in a typical Brillouin microscopy experiment…

Quantitative Methods · Quantitative Biology 2024-01-11 Hadi Mahmodi , Christopher G. Poulton , Mathew N. Lesley , Glenn Oldham , Hui Xin Ong , Steven J. Langford , Irina V. Kabakova

This research proposes a novel adjustable algorithm for reconstructing 3D body shapes from front and side silhouettes. Most recent silhouette-based approaches use a deep neural network trained by silhouettes and key points to estimate the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Aref Hemati , Azam Bastanfard

Dimensionality reduction algorithms like principal component analysis (PCA) are workhorses of machine learning and neuroscience, but each has well-known limitations. Variants of PCA are simple and interpretable, but not flexible enough to…

Machine Learning · Computer Science 2025-12-01 John J. Vastola , Samuel J. Gershman , Kanaka Rajan

The appearance of microcalcifications in mammograms is one of the early signs of breast cancer. So, early detection of microcalcification clusters (MCCs) in mammograms can be helpful for cancer diagnosis and better treatment of breast…

Computer Vision and Pattern Recognition · Computer Science 2012-01-31 Hajar Moradmand , Saeed Setayeshi , Hossein Khazaei Targhi

We introduce Principal Component Analysis guided Quantile Sampling (PCA QS), a novel sampling framework designed to preserve both the statistical and geometric structure of large scale datasets. Unlike conventional PCA, which reduces…

Methodology · Statistics 2026-01-13 Foo Hui-Mean , Yuan-chin Ivan Chang

Objective evaluation of new and improved methods for PET imaging requires access to images with ground truth, as can be obtained through simulation studies. However, for these studies to be clinically relevant, it is important that the…

Recent works have demonstrated the added value of dynamic amino acid positron emission tomography (PET) for glioma grading and genotyping, biopsy targeting, and recurrence diagnosis. However, most of these studies are exclusively based on…

Retrieval-Augmented Generation (RAG) has emerged as a powerful paradigm for grounding large language models in external knowledge sources, improving the precision of agents responses. However, high-dimensional language model embeddings,…

Machine Learning · Computer Science 2025-04-14 Arman Khaledian , Amirreza Ghadiridehkordi , Nariman Khaledian

Principal component analysis (PCA), a ubiquitous dimensionality reduction technique in signal processing, searches for a projection matrix that minimizes the mean squared error between the reduced dataset and the original one. Since…

Machine Learning · Computer Science 2022-08-25 Guilherme Dean Pelegrina , Leonardo Tomazeli Duarte

Principal component analysis (PCA) is often used for analyzing data in the most diverse areas. In this work, we report an integrated approach to several theoretical and practical aspects of PCA. We start by providing, in an intuitive and…

Computational Engineering, Finance, and Science · Computer Science 2021-06-09 Felipe L. Gewers , Gustavo R. Ferreira , Henrique F. de Arruda , Filipi N. Silva , Cesar H. Comin , Diego R. Amancio , Luciano da F. Costa

MR vascular Fingerprinting proposes to use the MR Fingerprinting framework to quantitatively and simultaneously map several microvascular characteristics at a sub-voxel scale. The initial implementation assessed the local blood oxygenation…