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It is now increasingly realized that the underlying mechanism which governs aging (ageing) is a complex interplay of genetic regulation and damage-accumulation. "Aging as a result of accumulation of 'faults' on cellular and molecular…

Tissues and Organs · Quantitative Biology 2011-03-31 Jicun Wang , Thomas Michelitsch , Arne Wunderlin , Ravi Mahadeva

Innovation and obsolescence describe the dynamics of ever-churning social and biological systems, from the development of economic markets to scientific and technological progress to biological evolution. They have been widely discussed,…

Here we study the effects of adopting different strategies against different opponent instead of adopting the same strategy against all of them in the prisoner dilemma structured in well-mixed populations. We consider an evolutionary…

Physics and Society · Physics 2015-05-14 Lucas Wardil , Jafferson K. L. da Silva

We present a simple model of adaptive radiations in evolution based on species competition. Competition is found to promote species divergence and branching, and to dampen the net species production. In the model simulations, high taxonomic…

Populations and Evolution · Quantitative Biology 2007-05-23 Birgitte Freiesleben De Blasio , Fabio Vittorio De Blasio

The unwelcome evolution of malignancy during cancer progression emerges through a selection process in a complex heterogeneous population structure. In the present work, we investigate evolutionary dynamics in a phenotypically heterogeneous…

Populations and Evolution · Quantitative Biology 2018-02-07 Ali Mahdipour Shirayeh , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

Multicellular collective migration is a ubiquitous strategy of cells to translocate spatially in diverse tissue environments to accomplish a wide variety of biological phenomena, viz. embryonic development, wound healing, and tumor…

Cell Behavior · Quantitative Biology 2022-01-20 Ushasi Roy , Tyler Collins , Mohit K. Jolly , Parag Katira

Predicting competitive outcomes typically requires fitting dynamical models to data, from which interaction strengths and coexistence indicators such as invasion criteria can be produced. Methods that allow to propagate parameter…

Populations and Evolution · Quantitative Biology 2025-04-10 Matthieu Paquet , Frédéric Barraquand

Competition for available resources is natural amongst coexisting species, and the fittest contenders dominate over the rest in evolution. The dynamics of this selection is studied using a simple linear model. It has similarities to…

Quantum Physics · Physics 2007-05-23 Apoorva Patel

Systems with simultaneous cooperation and competition among the elements are ubiquitous. In spite of their practical importance, knowledge on the evolution mechanism of this class of complex system is still very limit. In this work, by…

Physics and Society · Physics 2015-05-20 Xiu-Lian Xu , Chun-Hua Fu , Hui Chang , Da-Ren He

In human societies the probability of strategy adoption from a given person may be affected by the personal features. Now we investigate how an artificially imposed restricted ability to reproduce, overruling ones fitness, affects an…

Populations and Evolution · Quantitative Biology 2008-04-10 A. Szolnoki , M. Perc , G. Szabo

Using cyclic shear to drive a two dimensional granular system, we determine the structural characteristics for different inter-particle friction coefficients. These characteristics are the result of a competition between mechanical…

Soft Condensed Matter · Physics 2021-01-06 Xulai Sun , Walter Kob , Raphael Blumenfeld , Hua Tong , Yujie Wang , Jie Zhang

Evolutionary game dynamics are often studied in the context of different population structures. Here we propose a new population structure that is inspired by simple multicellular life forms. In our model, cells reproduce but can stay…

Populations and Evolution · Quantitative Biology 2016-05-26 Kamran Kaveh , Carl Veller , Martin A. Nowak

Bacteria regulate their motility through a variety of mechanisms, including quorum sensing (QS) and other density-dependent responses mediated by diffusible signals. While nonlinear density-dependent motility is well known in active-matter…

Populations and Evolution · Quantitative Biology 2026-01-21 Mattia Mattei , David Soriano-Paños , Alex Arenas

In the tumour microenvironment, cancer cells directly interact with both the immune system and the stroma. It is firmly established that the immune system, historically believed to be a major part of the body's defence against tumour…

Tissues and Organs · Quantitative Biology 2017-09-01 R J Seager , Cynthia Hajal , Fabian Spill , Roger D Kamm , Muhammad H Zaman

Natural selection has shaped the evolution of cells and multi-cellular organisms such that social cooperation can often be preferred over an individualistic approach to metabolic regulation. This paper extends a framework for dynamic…

Molecular Networks · Quantitative Biology 2021-01-28 David S. Tourigny

Natural Immune system plays a vital role in the survival of the all living being. It provides a mechanism to defend itself from external predates making it consistent systems, capable of adapting itself for survival incase of changes. The…

Artificial Intelligence · Computer Science 2011-03-11 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

We perform individual-based Monte Carlo simulations in a community consisting of two predator species competing for a single prey species, with the purpose of studying biodiversity stabilization in this simple model system. Predators are…

Populations and Evolution · Quantitative Biology 2018-07-11 Sheng Chen , Ulrich Dobramysl , Uwe C. Täuber

Death has long been overlooked in evolutionary algorithms. Recent research has shown that death (when applied properly) can benefit the overall fitness of a population and can outperform sub-sections of a population that are "immortal" when…

Neural and Evolutionary Computing · Computer Science 2021-09-29 Micah Burkhardt , Roman V. Yampolskiy

Combining a spatiotemporal, multi-agent based model of a foraging ecosystem with linear, genetically programmed rules for the agents' behaviors results in implicit, endogenous, objective functions and selection algorithms based on "natural…

Neural and Evolutionary Computing · Computer Science 2023-06-01 John C Stevenson

In social networks, it is conventionally thought that two individuals with more overlapped friends tend to establish a new friendship, which could be stated as homophily breeding new connections. While the recent hypothesis of maximum…

Social and Information Networks · Computer Science 2016-02-17 Jichang Zhao , Xiao Liang , Ke Xu
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