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Genomics are rapidly transforming medical practice and basic biomedical research, providing insights into disease mechanisms and improving therapeutic strategies, particularly in cancer. The ability to predict the future course of a…

Neural and Evolutionary Computing · Computer Science 2016-09-29 Safoora Yousefi , Congzheng Song , Nelson Nauata , Lee Cooper

Statistical models for predicting lung cancer have the potential to facilitate earlier diagnosis of malignancy and avoid invasive workup of benign disease. Many models have been published, but comparative studies of their utility in…

Designing modern oncology trials requires synthesizing evidence from prior studies to inform hypothesis generation and sample size determination. Trial designs based on incomplete or imprecise summaries can lead to misspecified hypotheses…

A combination of traditional image processing methods with advanced neural networks concretes a predictive and preventive healthcare paradigm. This study offers rapid, accurate, and non-invasive diagnostic solutions that can significantly…

With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer death in the United States. Lung cancer CT screening has been shown to reduce mortality by up to 40% and is now included in US screening guidelines.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Daniel Korat

Histo-genomic multimodal survival prediction has garnered growing attention for its remarkable model performance and potential contributions to precision medicine. However, a significant challenge in clinical practice arises when only…

Machine Learning · Computer Science 2025-03-17 Fengchun Liu , Linghan Cai , Zhikang Wang , Zhiyuan Fan , Jin-gang Yu , Hao Chen , Yongbing Zhang

Due to silence in early stages, lung cancer has been one of the most leading causes of mortality in cancer patients world-wide. Moreover, major symptoms of lung cancer are hard to differentiate with other respiratory disease symptoms such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Daeyoung Kim

There is currently great interest in applying neural networks to prediction tasks in medicine. It is important for predictive models to be able to use survival data, where each patient has a known follow-up time and event/censoring…

Machine Learning · Statistics 2020-02-12 Michael F. Gensheimer , Balasubramanian Narasimhan

In this paper, we propose a flexible model for survival analysis using neural networks along with scalable optimization algorithms. One key technical challenge for directly applying maximum likelihood estimation (MLE) to censored data is…

Machine Learning · Statistics 2021-12-07 Weijing Tang , Jiaqi Ma , Qiaozhu Mei , Ji Zhu

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

Survival prediction aims to evaluate the risk level of cancer patients. Existing methods primarily rely on pathology and genomics data, either individually or in combination. From the perspective of cancer pathogenesis, epigenetic changes,…

Machine Learning · Computer Science 2025-06-23 Haipeng Zhou , Sicheng Yang , Sihan Yang , Jing Qin , Lei Chen , Lei Zhu

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

Diffuse Large B-cell Lymphoma (DLBCL) is a lymphatic cancer involving one or more lymph nodes and extranodal sites. Its diagnostic and follow-up rely on Positron Emission Tomography (PET) and Computed Tomography (CT). After diagnosis, the…

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Baramee Sukumal , Aueaphum Aueawatthanaphisut

Survival prediction is a crucial task in the medical field and is essential for optimizing treatment options and resource allocation. However, current methods often rely on limited data modalities, resulting in suboptimal performance. In…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Binyu Zhang , Zhu Meng , Junhao Dong , Fei Su , Zhicheng Zhao

A comprehensive and reliable survival prediction model is of great importance to assist in the personalized management of Head and Neck Cancer (HNC) patients treated with curative Radiation Therapy (RT). In this work, we propose IMLSP, an…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Meixu Chen , Kai Wang , Jing Wang

Effective disaster management requires timely and accurate insights, yet traditional methods struggle to integrate multimodal data such as images, weather records, and textual reports. To address this, we propose DisasterNet-LLM, a…

Machine Learning · Computer Science 2025-07-01 Manaswi Kulahara , Gautam Siddharth Kashyap , Nipun Joshi , Arpita Soni

Accurately predicting the survival of cancer patients is crucial for personalized treatment. However, existing studies focus solely on the relationships between samples with known survival risks, without fully leveraging the value of…

Machine Learning · Computer Science 2025-07-23 Hailin Yue , Hulin Kuang , Jin Liu , Junjian Li , Lanlan Wang , Mengshen He , Jianxin Wang

Multi-modal biomedical time series (MBTS) data offers a holistic view of the physiological state, holding significant importance in various bio-medical applications. Owing to inherent noise and distribution gaps across different modalities,…

Machine Learning · Computer Science 2023-12-08 Hongbo Guo , Xinzi Xu , Hao Wu , Guoxing Wang

The progression of lung cancer implies the intrinsic ordinal relationship of lung nodules at different stages-from benign to unsure then to malignant. This problem can be solved by ordinal regression methods, which is between classification…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Yiming Lei , Hongming Shan , Junping Zhang