Related papers: Random traction yielding transition in epithelial …
We consider a system composed of a stack of weakly Josephson coupled superfluid layers with c-axis disorder in the form of random superfluid stiffnesses and vortex fugacities in each layer as well as random inter-layer coupling strengths.…
Using a mean field approach and simulation, we study the non-linear mechanical response of the vertex model (VM) of biological tissue under compression and dilation. The VM is known to exhibit a transition between rigid and fluid-like, or…
We focus on the probability distribution function (pdf) $P(\Delta \gamma; \gamma)$ where $\Delta \gamma$ are the {\em measured} strain intervals between plastic events in an athermal strained amorphous solids, and $\gamma$ measures the…
Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…
How internal forces are transduced into motion through soft, fluid membranes remains a fundamental question in the study of active systems. To investigate this coupling, we develop a minimal system consisting of a single ferromagnetic…
In this numerical study, measurements of the contact forces inside a periodic two-dimensional sheared system of soft frictional particles are reported. The distribution of normalized normal forces exhibits a gradual broadening with…
It is known that an object translating parallel to a soft wall in a viscous fluid produces hydro- dynamic stresses that deform the wall, which, in turn, results in a lift force on the object. Recent experiments with cylinders sliding under…
The rheological properties of biological tissues are core to processes such as cancer metastasis, wound healing and embryo development. The emergence of tissue and organ structures during morphogenesis requires the precise formation of…
A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on…
Amorphous solids such as coffee foam, toothpaste or mayonnaise display a transient creep flow when a stress $\Sigma$ is suddenly imposed. The associated strain rate is commonly found to decay in time as $\dot{\gamma} \sim t^{-\nu}$,…
Cell migration plays a fundamental role in numerous physiological processes, including embryonic development, wound healing, and cancer metastasis. While cell-cell adhesion is known to regulate motion by shaping cell morphology and…
Key traits of unicellular species, like cell size, often follow scale-free or self-similar distributions, hinting at the possibility of an underlying critical process. However, linking such empirical scaling laws to the critical regime of…
Cells not only can be motile by crawling but are also capable of non-motility active motions like periodic contraction or pulsation. In this work, based on a Voronoi cell model, we show how this non-motility activity affects the structure,…
Yield-stress materials, which require a sufficiently large forcing to flow, are currently ill-understood theoretically. To gain insight into their yielding transition, here we study numerically the rheology of a suspension of deformable…
Mechanical signaling plays a key role in biological processes like embryo development and cancer growth. One prominent way to probe mechanical properties of tissues is to study their response to externally applied forces. Using a…
Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. We present a phase-field model for simulating the motility of…
Recent experiments in various cell types have shown that two-dimensional tissues often display local nematic order, with evidence of extensile stresses manifest in the dynamics of topological defects. Using a mesoscopic model where tissue…
The behavior of a colloidal suspension of rod-like {\it fd} viruses in the nematic phase, subjected to steady state and transient shear flows is studied. The monodisperse nature of these rods combined with relatively small textural…
During migration, amoeboid cells perform a cycle of quasi-periodic repetitive events (motility cycle). the cell length and the strain energy exchanged with the substrate oscillate in time with an average frequency, f, on top of which are…
Understanding the rolling and adhesion behavior of a cell on the vascular surface under viscous shear flow is important to better understand many biological processes. One of the important examples is the adhesion of the leukocytes onto…