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Deep learning-based methods have made significant achievements in music source separation. However, obtaining good results while maintaining a low model complexity remains challenging in super wide-band music source separation. Previous…

Audio and Speech Processing · Electrical Eng. & Systems 2024-01-25 Weinan Tong , Jiaxu Zhu , Jun Chen , Shiyin Kang , Tao Jiang , Yang Li , Zhiyong Wu , Helen Meng

Chemical mapping methods probe RNA structure by revealing and leveraging correlations of a nucleotide's structural accessibility or flexibility with its reactivity to various chemical probes. Pioneering work by Lucks and colleagues has…

Biomolecules · Quantitative Biology 2013-04-04 Matthew G. Seetin , Wipapat Kladwang , J. P. Bida , Rhiju Das

DNA storage technology offers new possibilities for addressing massive data storage due to its high storage density, long-term preservation, low maintenance cost, and compact size. To improve the reliability of stored information, base…

Machine Learning · Computer Science 2024-09-24 Bowen Liu , Jiankun Li

The amount of high-dimensional large-scale RNA sequencing data derived from multiple heterogeneous sources has increased exponentially in biological science. During data collection, significant technical noise or errors may occur. To…

Applications · Statistics 2025-06-24 Xiaolu Jiang , Wei Liu

We present a novel scheme to boost detection power for kernel maximum mean discrepancy based sequential change-point detection procedures. Our proposed scheme features an optimal sub-sampling of the history data before the detection…

Methodology · Statistics 2023-01-19 Song Wei , Chaofan Huang

Selecting hyperparameters for unsupervised learning problems is challenging in general due to the lack of ground truth for validation. Despite the prevalence of this issue in statistics and machine learning, especially in clustering…

Machine Learning · Statistics 2020-02-04 Xinjie Fan , Yuguang Yue , Purnamrita Sarkar , Y. X. Rachel Wang

By combining various cancer cell line (CCL) drug screening panels, the size of the data has grown significantly to begin understanding how advances in deep learning can advance drug response predictions. In this paper we train >35,000…

Accurate cell type annotation across datasets is a key challenge in single-cell analysis. snRNA-seq enables profiling of frozen or difficult-to-dissociate tissues, complementing scRNA-seq by capturing fragile or rare cell types. However,…

Genomics · Quantitative Biology 2026-03-10 Xiran Chen , Quan Zou , Qinyu Cai , Xiaofeng Chen , Weikai Li , Yansu Wang

We introduce hmmSeq, a model-based hierarchical Bayesian technique for detecting differentially expressed genes from RNA-seq data. Our novel hmmSeq methodology uses hidden Markov models to account for potential co-expression of neighboring…

Applications · Statistics 2015-09-17 Shiqi Cui , Subharup Guha , Marco A. R. Ferreira , Allison N. Tegge

Hyperspectral images are crucial for many research works. Spectral super-resolution (SSR) is a method used to obtain high spatial resolution (HR) hyperspectral images from HR multispectral images. Traditional SSR methods include…

Image and Video Processing · Electrical Eng. & Systems 2020-12-09 Jiang He , Jie Li , Qiangqiang Yuan , Huanfeng Shen , Liangpei Zhang

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

Fitting models with high predictive accuracy that include all relevant but no irrelevant or redundant features is a challenging task on data sets with similar (e.g. highly correlated) features. We propose the approach of tuning the…

Machine Learning · Statistics 2022-03-23 Andrea Bommert , Jörg Rahnenführer , Michel Lang

Pretraining large language models effectively requires strategic data selection, blending and ordering. However, key details about data mixtures especially their scalability to longer token horizons and larger model sizes remain…

Computation and Language · Computer Science 2024-12-23 Steven Feng , Shrimai Prabhumoye , Kezhi Kong , Dan Su , Mostofa Patwary , Mohammad Shoeybi , Bryan Catanzaro

Functional or non-coding RNAs are attracting more attention as they are now potentially considered valuable resources in the development of new drugs intended to cure several human diseases. The identification of drugs targeting the…

Genomics · Quantitative Biology 2019-12-25 Muhammad Nabeel Asima , Muhammad Imran Malik , Andreas Dengela , Sheraz Ahmed

This paper presents enhancement strategies for the Hermitian and skew-Hermitian splitting method based on gradient iterations. The spectral properties are exploited for the parameter estimation, often resulting in a better convergence. In…

Numerical Analysis · Mathematics 2020-07-08 Qinmeng Zou , Frederic Magoules

With the frequent use of self-supervised monocular depth estimation in robotics and autonomous driving, the model's efficiency is becoming increasingly important. Most current approaches apply much larger and more complex networks to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Wang Boya , Wang Shuo , Ye Dong , Dou Ziwen

Collecting and annotating real-world data for the development of object detection models is a time-consuming and expensive process. In the military domain in particular, data collection can also be dangerous or infeasible. Training models…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Frank A. Ruis , Alma M. Liezenga , Friso G. Heslinga , Luca Ballan , Thijs A. Eker , Richard J. M. den Hollander , Martin C. van Leeuwen , Judith Dijk , Wyke Huizinga

Recent advances in technology have enabled the measurement of RNA levels for individual cells. Compared to traditional tissue-level bulk RNA-seq data, single cell sequencing yields valuable insights about gene expression profiles for…

Applications · Statistics 2019-04-16 Lingxue Zhu , Jing Lei , Bernie Devlin , Kathryn Roeder

Hyperparameters in machine learning (ML) have received a fair amount of attention, and hyperparameter tuning has come to be regarded as an important step in the ML pipeline. But just how useful is said tuning? While smaller-scale…

Machine Learning · Computer Science 2022-09-05 Moshe Sipper

As a long-standing problem in computer vision, face detection has attracted much attention in recent decades for its practical applications. With the availability of face detection benchmark WIDER FACE dataset, much of the progresses have…

Computer Vision and Pattern Recognition · Computer Science 2019-01-31 Shifeng Zhang , Rui Zhu , Xiaobo Wang , Hailin Shi , Tianyu Fu , Shuo Wang , Tao Mei , Stan Z. Li