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Recent advancements in protein structure prediction, particularly AlphaFold2, have revolutionized structural biology by achieving near-experimental accuracy ($\text{average RMSD} < 1.5\text{\AA}$). However, the computational demands of…

Biomolecules · Quantitative Biology 2025-06-09 Joongwon Chae , Zhenyu Wang , Ijaz Gul , Jiansong Ji , Zhenglin Chen , Peiwu Qin

This article presents an automatic approach to quickly derive a good solution for hardware resource partition and task granularity for task-based parallel applications on heterogeneous many-core architectures. Our approach employs a…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-10 Peng Zhang , Jianbin Fang , Canqun Yang , Chun Huang , Tao Tang , Zheng Wang

Currently, training large-scale deep learning models is typically achieved through parallel training across multiple GPUs. However, due to the inherent communication overhead and synchronization delays in traditional model parallelism…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Xiuyuan Guo , Chengqi Xu , Guinan Guo , Feiyu Zhu , Changpeng Cai , Peizhe Wang , Xiaoming Wei , Junhao Su , Jialin Gao

Deep reinforcement learning has led to dramatic breakthroughs in the field of artificial intelligence for the past few years. As the amount of rollout experience data and the size of neural networks for deep reinforcement learning have…

Machine Learning · Computer Science 2024-11-11 Zhihong Liu , Xin Xu , Peng Qiao , Dongsheng Li

Code localization constitutes a key bottleneck in automated software development pipelines. While concurrent tool execution can enhance discovery speed, current agents demonstrate a 34.9\% redundant invocation rate, which negates…

Artificial Intelligence · Computer Science 2026-01-28 Ke Xu , Siyang Xiao , Ming Liang , Yichen Yu , Zhixiang Wang , Jingxuan Xu , Dajun Chen , Wei Jiang , Yong Li

How can we design protein sequences folding into the desired structures effectively and efficiently? AI methods for structure-based protein design have attracted increasing attention in recent years; however, few methods can simultaneously…

Artificial Intelligence · Computer Science 2023-04-14 Zhangyang Gao , Cheng Tan , Pablo Chacón , Stan Z. Li

The increasingly deeper neural networks hinder the democratization of privacy-enhancing distributed learning, such as federated learning (FL), to resource-constrained devices. To overcome this challenge, in this paper, we advocate the…

Machine Learning · Computer Science 2024-01-25 Zheng Lin , Guangyu Zhu , Yiqin Deng , Xianhao Chen , Yue Gao , Kaibin Huang , Yuguang Fang

In cross-device Federated Learning (FL) environments, scaling synchronous FL methods is challenging as stragglers hinder the training process. Moreover, the availability of each client to join the training is highly variable over time due…

Machine Learning · Computer Science 2023-04-17 Tuo Zhang , Lei Gao , Sunwoo Lee , Mi Zhang , Salman Avestimehr

Federated learning is a recent development in the machine learning area that allows a system of devices to train on one or more tasks without sharing their data to a single location or device. However, this framework still requires a…

Machine Learning · Computer Science 2024-01-11 Guangyao Zheng , Michael A. Jacobs , Vladimir Braverman , Vishwa S. Parekh

Transformer models have emerged as the leading approach for achieving state-of-the-art performance across various application domains, serving as the foundation for advanced large-scale deep learning (DL) models. However, efficiently…

Machine Learning · Computer Science 2024-09-06 Yujie Wang , Youhe Jiang , Xupeng Miao , Fangcheng Fu , Shenhan Zhu , Xiaonan Nie , Yaofeng Tu , Bin Cui

GPUs have been favored for training deep learning models due to their highly parallelized architecture. As a result, most studies on training optimization focus on GPUs. There is often a trade-off, however, between cost and efficiency when…

Training on edge devices poses several challenges as these devices are generally resource-constrained, especially in terms of power. State-of-the-art techniques at the device level reduce the GPU frequency to enforce power constraints,…

Machine Learning · Computer Science 2025-02-26 Mohamed Aboelenien Ahmed , Kilian Pfeiffer , Heba Khdr , Osama Abboud , Ramin Khalili , Jörg Henkel

Federated learning aims to protect users' privacy while performing data analysis from different participants. However, it is challenging to guarantee the training efficiency on heterogeneous systems due to the various computational…

Machine Learning · Computer Science 2021-08-23 Junyu Luo , Jianlei Yang , Xucheng Ye , Xin Guo , Weisheng Zhao

Federated Adversarial Training (FAT) can supplement robustness against adversarial examples to Federated Learning (FL), promoting a meaningful step toward trustworthy AI. However, FAT requires large models to preserve high accuracy while…

Machine Learning · Computer Science 2025-04-16 Minxue Tang , Yitu Wang , Jingyang Zhang , Louis DiValentin , Aolin Ding , Amin Hass , Yiran Chen , Hai "Helen" Li

The growing demand for real-time DNN applications on edge devices necessitates faster inference of increasingly complex models. Although many devices include specialized accelerators (e.g., mobile GPUs), dynamic control-flow operators and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-15 Chong Tang , Hao Dai , Jagmohan Chauhan

Training recommendation models pose significant challenges regarding resource utilization and performance. Prior research has proposed an approach that categorizes embeddings into popular and non-popular classes to reduce the training time…

Information Retrieval · Computer Science 2024-04-09 Yassaman Ebrahimzadeh Maboud , Muhammad Adnan , Divya Mahajan , Prashant J. Nair

Predicting of airfoil aerodynamic performance is a key part of aircraft design optimization, but the traditional methods (such as wind tunnel test and CFD simulation) have the problems of high cost and low efficiency, and the existing…

Neural and Evolutionary Computing · Computer Science 2025-06-10 MaolinYang , Yaohui Wang , Pingyu Jiang

How can neural networks be trained on large-volume temporal data efficiently? To compute the gradients required to update parameters, backpropagation blocks computations until the forward and backward passes are completed. For temporal…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Mateusz Malinowski , Dimitrios Vytiniotis , Grzegorz Swirszcz , Viorica Patraucean , Joao Carreira

Synchronous Reinforcement Learning (RL) post-training has emerged as a crucial step for enhancing Large Language Models (LLMs) with diverse capabilities. However, many systems designed to accelerate RL post-training still suffer from low…

Diffusion models have revolutionized generative tasks through high-fidelity outputs, yet flow matching (FM) offers faster inference and empirical performance gains. However, current foundation FM models are computationally prohibitive for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Johannes Schusterbauer , Ming Gui , Frank Fundel , Björn Ommer