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With the advanced imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

Applications · Statistics 2020-12-10 Esteban Fernández Morales , Cong Zhang , Guanghua Xiao , Chul Moon , Qiwei Li

Background and Objective:Computer-aided diagnosis (CAD) systems promote diagnosis effectiveness and alleviate pressure of radiologists. A CAD system for lung cancer diagnosis includes nodule candidate detection and nodule malignancy…

Image and Video Processing · Electrical Eng. & Systems 2022-01-17 Shaohua Zheng , Zhiqiang Shen , Chenhao Peia , Wangbin Ding , Haojin Lin , Jiepeng Zheng , Lin Pan , Bin Zheng , Liqin Huang

Statistical models for predicting lung cancer have the potential to facilitate earlier diagnosis of malignancy and avoid invasive workup of benign disease. Many models have been published, but comparative studies of their utility in…

For most if not all cancers, prognosis is of significant importance, and extensive modeling research has been conducted. With the genetic nature of cancer, in the past two decades, multiple types of molecular data (such as gene expressions…

Applications · Statistics 2020-06-09 Sanguo Zhang , Yu Fan , Tingyan Zhong , Shuangge Ma

Laryngeal cancer imaging research lacks standardised datasets to enable reproducible deep learning (DL) model development. We present LaryngealCT, a curated benchmark of 1,029 computed tomography (CT) scans aggregated from six collections…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Nivea Roy , Son Tran , Atul Sajjanhar , K. Devaraja , Prakashini Koteshwara , Yong Xiang , Divya Rao

Motivated by the question, "Can we generate tumors with desired attributes?'' this study leverages radiomics features to explore the feasibility of generating synthetic tumor images. Characterized by its low-dimensional yet biologically…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Inye Na , Jonghun Kim , Eun Sook Ko , Hyunjin Park

The development of machine learning models for CT imaging depends on the availability of large, high-quality, and diverse annotated datasets. Although large volumes of CT images and reports are readily available in clinical picture…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Samuel Church , Joshua D. Warner , Danyal Maqbool , Xin Tie , Junjie Hu , Meghan G. Lubner , Tyler J. Bradshaw

Public imaging datasets are critical for the development and evaluation of automated tools in cancer imaging. Unfortunately, many do not include annotations or image-derived features, complicating their downstream analysis. Artificial…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Deepa Krishnaswamy , Dennis Bontempi , Vamsi Thiriveedhi , Davide Punzo , David Clunie , Christopher P Bridge , Hugo JWL Aerts , Ron Kikinis , Andrey Fedorov

Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

Machine Learning · Computer Science 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

Breast cancer is the malignant tumor that causes the highest number of cancer deaths in females. Digital mammograms (DM or 2D mammogram) and digital breast tomosynthesis (DBT or 3D mammogram) are the two types of mammography imagery that…

Computer Vision and Pattern Recognition · Computer Science 2020-03-02 Gongbo Liang , Xiaoqin Wang , Yu Zhang , Xin Xing , Hunter Blanton , Tawfiq Salem , Nathan Jacobs

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

The National Cancer Institute (NCI) Image Data Commons (IDC) offers publicly available cancer radiology collections for cloud computing, crucial for developing advanced imaging tools and algorithms. Despite their potential, these…

Radiomics is an exciting new area of texture research for extracting quantitative and morphological characteristics of pathological tissue. However, to date, only single images have been used for texture analysis. We have extended radiomic…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Vishwa S. Parekh , John Laterra , Chetan Bettegowda , Alex E. Bocchieri , Jay J. Pillai , Michael A. Jacobs

The aim of this study was to develop a model to accurately identify corresponding points between organ segmentations of different patients for radiotherapy applications. A model for simultaneous correspondence and interpolation estimation…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Edward G. A. Henderson , Marcel van Herk , Andrew F. Green , Eliana M. Vasquez Osorio

Purpose: Radiotherapy presents unique challenges and clinical requirements for longitudinal tumor and organ-at-risk (OAR) prediction during treatment. The challenges include tumor inflammation/edema and radiation-induced changes in organ…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Donghoon Lee , Sadegh R Alam , Jue Jiang , Pengpeng Zhang , Saad Nadeem , Yu-Chi Hu

Lung cancer, particularly in its advanced stages, remains a leading cause of death globally. Though early detection via low-dose computed tomography (CT) is promising, the identification of high-risk factors crucial for surgical mode…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Xiaotong Fu , Xiangyu Meng , Jing Zhou , Ying Ji

Integrating multi-omics datasets through data-driven analysis offers a comprehensive understanding of the complex biological processes underlying various diseases, particularly cancer. Graph Neural Networks (GNNs) have recently demonstrated…

Machine Learning · Computer Science 2025-08-11 Jielong Lu , Zhihao Wu , Jiajun Yu , Jiajun Bu , Haishuai Wang

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

Purpose: The main purpose of this study was to assess the reliability of shape and heterogeneity features in both Positron Emission Tomography (PET) and low-dose Computed Tomography (CT) components of PET/CT. A secondary objective was to…

Computer Vision and Pattern Recognition · Computer Science 2016-10-06 Marie-Charlotte Desseroit , Florent Tixier , Wolfgang Weber , Barry A Siegel , Catherine Cheze Le Rest , Dimitris Visvikis , Mathieu Hatt

The computer-aided disease diagnosis from radiomic data is important in many medical applications. However, developing such a technique relies on annotating radiological images, which is a time-consuming, labor-intensive, and expensive…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Nehal A. Parikh , Lili He
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