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This paper presents and validates a novel lung nodule classification algorithm that uses multifractal features found in X-ray images. The proposed method includes a pre-processing step where two enhancement techniques are applied: histogram…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Isabella María Sierra-Ponce , Angela Mireya León-Mecías , Damian Valdés-Santiago

Non-small-cell lung cancer (NSCLC) represents approximately 80-85% of lung cancer diagnoses and is the leading cause of cancer-related death worldwide. Recent studies indicate that image-based radiomics features from positron emission…

Computational fluid dynamics (CFD) models are emerging as tools for assisting in diagnostic assessment of cardiovascular disease. Recent advances in image segmentation has made subject-specific modelling of the cardiovascular system a…

Quantitative Methods · Quantitative Biology 2021-01-18 Mitchel J. Colebank , L. Mihaela Paun , M. Umar Qureshi , Naomi Chesler , Dirk Husmeier , Mette S. Olufsen , Laura Ellwein Fix

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

In this study, we introduce statistical modeling methods for pneumothorax deformation using paired cone-beam computed tomography (CT) images. We designed a deformable mesh registration framework for shape changes involving non-linear…

Computational Geometry · Computer Science 2020-12-25 Megumi Nakao , Hinako Maekawa , Katsutaka Mineura , Toyofumi F. Chen-Yoshikawa , Hiroshi Date , Tetsuya Matsuda

Automated semantic image segmentation is an essential step in quantitative image analysis and disease diagnosis. This study investigates the performance of a deep learning-based model for lung segmentation from CT images for normal and…

In lung radiotherapy, the primary objective is to optimize treatment outcomes by minimizing exposure to healthy tissues while delivering the prescribed dose to the target volume. The challenge lies in accounting for lung tissue motion due…

Medical Physics · Physics 2024-11-26 Frederic Madesta , Lukas Wimmert , Tobias Gauer , René Werner , Thilo Sentker

High-resolution volumetric computed tomography (CT) is essential for accurate diagnosis and treatment planning in thoracic diseases; however, it is limited by radiation dose and hardware costs. We present the Transformer Volumetric…

Objective: Lung ultrasonography is a significant advance toward a harmless lung imagery system. This work has investigated the automatic localization of diagnostically significant features in lung ultrasound pictures which are Pleural line,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Maria Farahi , Joan Aranda , Hessam Habibian , Alicia Casals

Early detection of lung cancer is crucial as it increases the chances of successful treatment. Automatic lung image segmentation assists doctors in identifying diseases such as lung cancer, COVID-19, and respiratory disorders. However, lung…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Sadjad Rezvani , Mansoor Fateh , Yeganeh Jalali , Amirreza Fateh

Quantitative descriptors convert high-dimensional medical images into low-dimensional features capable of differentiating organ shapes that correlate with injury or disease progression for diagnostic purposes. An important example is aortic…

Tissues and Organs · Quantitative Biology 2025-11-19 Cooper Bruno , Tiago Cecchi , Joseph A. Pugar , Luka Pocivavsek , Newell Washburn

Propagation-based phase-contrast X-ray imaging is a promising technique for in~vivo medical imaging, offering lower radiation doses than traditional attenuation-based imaging. Previous studies have focused on X-ray energies below 50 keV for…

Automated segmentation of anatomical structures is a crucial step in image analysis. For lung segmentation in computed tomography, a variety of approaches exist, involving sophisticated pipelines trained and validated on different datasets.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Johannes Hofmanninger , Florian Prayer , Jeanny Pan , Sebastian Rohrich , Helmut Prosch , Georg Langs

Purpose: Interpreting chest radiographs (CXR) remains challenging due to the ambiguity of overlapping structures such as the lungs, heart, and bones. To address this issue, we propose a novel method for extracting fine-grained anatomical…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Constantin Seibold , Alexander Jaus , Matthias A. Fink , Moon Kim , Simon Reiß , Ken Herrmann , Jens Kleesiek , Rainer Stiefelhagen

Carbon-ion radiotherapy provides high dose conformity for lung cancer, but its benefit is limited by two sources of uncertainties: interplay between scanned beam delivery and tumor motion, and dose modulation from heterogeneous lung tissue.…

Medical Physics · Physics 2026-02-18 Maria Chiara Martire , Lennart Volz , Marco Durante , Christian Graeff

This study performs a comprehensive evaluation of quantitative measurements as extracted from automated deep-learning-based segmentation methods, beyond traditional Dice Similarity Coefficient assessments, focusing on six quantitative…

Image and Video Processing · Electrical Eng. & Systems 2025-04-24 Obed Korshie Dzikunu , Amirhossein Toosi , Shadab Ahamed , Sara Harsini , Francois Benard , Xiaoxiao Li , Arman Rahmim

The paper presents and comparatively analyses several deep learning approaches to automatically detect tuberculosis related lesions in lung CTs, in the context of the ImageClef 2020 Tuberculosis task. Three classes of methods, different…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 Radu Miron , Cosmin Moisii , Mihaela Breaban

The elasticity of soft tissues has been widely considered as a characteristic property to differentiate between healthy and vicious tissues and, therefore, motivated several elasticity imaging modalities, such as Ultrasound Elastography,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-30 Weiguo Cao , Marc J. Pomeroy , Zhengrong Liang , Yongfeng Gao , Yongyi Shi , Jiaxing Tan , Fangfang Han , Jing Wang , Jianhua Ma , Hongbin Lu , Almas F. Abbasi , Perry J. Pickhardt

Tumor shape plays a critical role in influencing both growth and metastasis. We introduce a novel topological radiomic feature derived from persistent homology to characterize tumor shape, focusing on its association with time-to-event…

Methodology · Statistics 2025-12-08 Yuhyeong Jang , Tu Dan , Eric Vu , Chul Moon

Background. Radiomic features, derived from a region of interest (ROI) in medical images, are valuable as prognostic factors. Selecting an appropriate ROI is critical, and many recent studies have focused on leveraging multiple ROIs by…