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We determine conditions under which a random biochemical system is likely to contain a subsystem that is both autocatalytic and able to survive on some ambient `food' source. Such systems have previously been investigated for their…

Molecular Networks · Quantitative Biology 2007-05-23 Elchanan Mossel , Mike Steel

This paper proposes a control theoretic framework to model and analyze the self-organized pattern formation of molecular concentrations in biomolecular communication networks, emerging applications in synthetic biology. In biomolecular…

Molecular Networks · Quantitative Biology 2019-01-08 Yutaka Hori , Hiroki Miyazako , Soichiro Kumagai , Shinji Hara

We show that active transport processes in biological systems can be understood through a local equilibrium description formulated at the mesoscale, the scale to describe stochastic processes. This new approach uses the method established…

Soft Condensed Matter · Physics 2007-05-23 S. Kjelstrup , J. M. Rubi , D. Bedeaux

This paper presents the foundation for a decomposition theory for Boolean networks, a type of discrete dynamical system that has found a wide range of applications in the life sciences, engineering, and physics. Given a Boolean network…

Dynamical Systems · Mathematics 2022-06-10 Claus Kadelka , Reinhard Laubenbacher , David Murrugarra , Alan Veliz-Cuba , Matthew Wheeler

We analyze a model of interacting agents (e.g. prebiotic chemical species) which are represended by nodes of a network, whereas their interactions are mapped onto directed links between these nodes. On a fast time scale, each agent follows…

Populations and Evolution · Quantitative Biology 2009-11-13 Adrian M. Seufert , Frank Schweitzer

In this paper, we propose Diffusion Domain Expansion (DDE), a method that efficiently extends pre-trained diffusion models to generate larger objects and handle more complex conditioning beyond their original capabilities. Our method…

Machine Learning · Computer Science 2026-05-25 Egor Lifar , Semyon Savkin , Timur Garipov , Shangyuan Tong , Tommi Jaakkola

We show that finite-size, disordered molecular networks can mediate highly efficient, coherent excitation transfer which is robust against ambient dephasing and associated with strong multi-site entanglement. Such optimal, random molecular…

Developing a mathematical understanding of autocatalysis in reaction networks has both theoretical and practical implications. We review definitions of autocatalytic networks and prove some properties for minimal autocatalytic subnetworks…

Molecular Networks · Quantitative Biology 2023-11-14 Praful Gagrani , Victor Blanco , Eric Smith , David Baum

Recently, plenty research has been done on discovering the role of energy dissipation in biological networks, most of which focus on the relationship of dissipation and functionality. However, the development of networks science urged us to…

Biological Physics · Physics 2026-05-20 Bowen Shi , Long Qian , Qi Ouyang

Normal and anomalous diffusion are ubiquitous in many complex systems [1] . Here, we define a time and space generalized diffusion equation (GDE), which uses fractional-time derivatives and transformed d-path Laplacian operators on…

Physics and Society · Physics 2022-02-02 Fernando Diaz-Diaz , Ernesto Estrada

Systems whose time evolutions are entirely deterministic can nevertheless be studied probabilistically, i.e. in terms of the evolution of probability distributions rather than individual trajectories. This approach is central to the…

Dynamical Systems · Mathematics 2019-09-06 S. Richard Taylor

The power distribution system is evolving in the form of an intelligent grid. The proliferation of distributed energy resources (DERs) makes the previously passive system active and more complicated. With the adoption of de-carbonization…

Systems and Control · Electrical Eng. & Systems 2024-06-27 Santosh Sharma

Coupling cyber and physical systems gives rise to numerous engineering challenges and opportunities. An important challenge is the contagion of failure from one system to another, which can lead to large-scale cascading failures. However,…

Social and Information Networks · Computer Science 2017-07-14 Ali Behfarnia , Ali Eslami

Conformational transitions are ubiquitous in biomolecular systems, have significant functional roles and are subject to evolutionary pressures. Here we provide a first theoretical framework for topological transition, i.e. conformational…

Disordered Systems and Neural Networks · Physics 2015-09-02 Alireza Mashaghi , Abolfazl Ramezanpour

Accurate and efficient numerical simulation of ammonia combustion is critical for advancing ammonia-based energy systems, where turbulent flame dynamics and pollutant formation strongly affect practical applicability. However, such…

Fluid Dynamics · Physics 2025-09-26 Ke Xiao , Yangchen Xu , Han Li , Zhi X. Chen

We study a stochastic differential equation driven by a Poisson point process, which models continuous changes in a population's environment, as well as the stochastic fixation of beneficial mutations that might compensate for this change.…

Probability · Mathematics 2017-07-21 Elma Nassar , Etienne Pardoux

The dynamics of a chemical reaction network (CRN) is often modelled under the assumption of mass action kinetics by a system of ordinary differential equations (ODEs) with polynomial right-hand sides that describe the time evolution of…

Dynamical Systems · Mathematics 2023-01-05 Radek Erban , Hye-Won Kang

In the quest for controlled thermonuclear fusion, tokamaks present complex challenges in understanding burning plasma dynamics. This study introduces a multi-region multi-timescale transport model, employing Neural Ordinary Differential…

Plasma Physics · Physics 2024-03-05 Zefang Liu , Weston M. Stacey

We consider an evolutionary PDE system coupling the Cahn-Hilliard equation with singular potential, mass source and transport effects, to a Brinkman-type relation for the macroscopic velocity field and to a further equation describing the…

Analysis of PDEs · Mathematics 2024-11-20 Giulio Schimperna

Chemical reaction network theory is a powerful framework to describe and analyze chemical systems. While much about the concentration profile in an equilibrium state can be determined in terms of the graph structure, the overall reaction's…

Molecular Networks · Quantitative Biology 2024-02-29 Tomoharu Suda