English

Random autocatalytic networks

Molecular Networks 2007-05-23 v2 Combinatorics Populations and Evolution

Abstract

We determine conditions under which a random biochemical system is likely to contain a subsystem that is both autocatalytic and able to survive on some ambient `food' source. Such systems have previously been investigated for their relevance to origin-of-life models. In this paper we extend earlier work, by finding precisely the order of catalysation required for the emergence of such self-sustaining autocatalytic networks. This answers questions raised in earlier papers, yet also allows for a more general class of models. We also show that a recently-described polynomial time algorithm for determining whether a catalytic reaction system contains an autocatalytic, self-sustaining subsystem is unlikely to adapt to allow inhibitory catalysation - in this case we show that the associated decision problem is NP-complete.

Keywords

Cite

@article{arxiv.q-bio/0406044,
  title  = {Random autocatalytic networks},
  author = {Elchanan Mossel and Mike Steel},
  journal= {arXiv preprint arXiv:q-bio/0406044},
  year   = {2007}
}