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The current state of the art in structural biology is led by NMR, X-ray crystallography and TEM investigations. These powerful tools however all rely on averaging over a large ensemble of molecules. Here, we present an alternative concept…

Atomic and Molecular Clusters · Physics 2015-12-15 Tatiana Latychevskaia , Jean-Nicolas Longchamp , Conrad Escher , Hans-Werner Fink

Advanced accelerator-based light sources such as free electron lasers (FEL) accelerate highly relativistic electron beams to generate incredibly short (10s of femtoseconds) coherent flashes of light for dynamic imaging, whose brightness…

Accelerator Physics · Physics 2024-07-19 Alexander Scheinker

X-ray free electron laser (XFEL) experiments have brought unique capabilities and opened new directions in research, such as creating new states of matter or directly measuring atomic motion. One such area is the ability to use finely…

Advanced materials often consist of multiple elements which are arranged in a complicated structure. Quantitative scanning transmission electron microscopy is useful to determine the composition and thickness of nanostructures at the atomic…

Applied Physics · Physics 2024-05-17 Zezhong Zhang , Ivan Lobato , Annick De Backer , Sandra Van Aert , Peter Nellist

X-ray free electron lasers (FELs) have been proposed to be constructed both at SLAC in the form of the so-called Linac Coherent Light Source as well as at DESY, where the so-called XFEL laboratory is part of the design of the…

High Energy Physics - Phenomenology · Physics 2007-05-23 A. Ringwald

Material processing with femtosecond lasers has attracted enormous attention because of its potential for technology and industrial applications. In parallel, time-resolved x-ray diffraction has been successfully used to study ultrafast…

Using a time-resolved detection scheme in scanning transmission X-ray microscopy (STXM) we measured element resolved ferromagnetic resonance (FMR) at microwave frequencies up to 10\,GHz and a spatial resolution down to 20\,nm at two…

Mesoscale and Nanoscale Physics · Physics 2019-07-01 T. Schaffers , T. Feggeler , S. Pile , R. Meckenstock , M. Buchner , D. Spoddig , V. Ney , M. Farle , H. Wende , S. Wintz , M. Weigand , H. Ohldag , K. Ollefs , A. Ney

Two-color X-ray imaging with Free Electron Laser pulses offers a powerful approach for probing ultrafast structural dynamics in nanoscale systems, combining (near-)atomic spatial resolution with femtosecond temporal precision. The first…

We developed a Bessel light sheet fluorescence microscopy (LSFM) system to enable high-speed, wide-field intra-vital imaging of zebrafish and other thick biological samples. This system uses air objectives for the convenient mounting of…

Optics · Physics 2023-11-07 Chuhui Wang , Jiaju Chen , Cuiyi Peng , Zhenglin Chen , Dongmei Yu , Peiwu Qin

Coded apertures, traditionally employed in x-ray astronomy for imaging celestial objects, are now being adapted for micro-scale applications, particularly in studying microscopic specimens with synchrotron light diffraction. In this paper,…

Signal Processing · Electrical Eng. & Systems 2024-05-22 Doğa Gürsoy , Dina Sheyfer , Michael Wojcik , Wenjun Liu , Jonathan Tischler

The current progress of materials science regarding multifunctional materials (MFM) has put forward the challenges to understand the microscopic origin of their properties. Most of such MFMs have magneto-elastic correlations. To investigate…

Materials Science · Physics 2015-06-02 Aga Shahee , Shivani Sharma , K. Singh , N. P. Lalla , P. Chaddah

Ptychography has become prominent at synchrotron facilities worldwide for characterizing biological and material specimens' topological structures and properties at the nanometer or atomic scale, due to its lens - less, highly quantitative…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Tao Liu , Bingyang Wang , JiangTao Zhao , Maik Kahnt , Fucai Zhang

To leverage advancements in machine learning for metallic materials design and property prediction, it is crucial to develop a data-reduced representation of metal microstructures that surpasses the limitations of current physics-based…

X-ray free electron laser (XFEL) can provide X-ray light with about four order of magnitude higher flux than synchrotron radiation. Pulse light from XFEL interacts with the target and the resulting photons are collected by detectors. The…

Instrumentation and Detectors · Physics 2021-10-13 Shuo Zhang , Jing-Kai Xia , Xu-Dong Ju

Exciting electrons in solids with intense light pulses offers the possibility of generating new states of matter through nonthermal means and controlling their macroscopic properties on femto- to picosecond timescales. One way to manipulate…

Materials Science · Physics 2021-10-07 Alfred Zong , Anshul Kogar , Nuh Gedik

Perhaps surprisingly, the total electron microscopy (EM) data collected to date is less than a cubic millimeter. Consequently, there is an enormous demand in the materials and biological sciences to image at greater speed and lower dosage,…

Computer Vision and Pattern Recognition · Computer Science 2016-12-06 Suhas Sreehari , S. V. Venkatakrishnan , Katherine L. Bouman , Jeffrey P. Simmons , Lawrence F. Drummy , Charles A. Bouman

The accuracy of the information that can be extracted from electron diffraction patterns is often limited by the presence of optical distortions. Existing distortion characterization techniques typically require knowledge of the reciprocal…

Typical parameters of electron bunches available now in undulator X-ray FELs enable generation of induced radiation in crystal-based X-ray VFEL. An important peculiarity of an undulator X-ray FEL is electron bunch spatial modulation with…

Plasma Physics · Physics 2024-07-25 V. G. Baryshevsky

Electron microscopy techniques are instrumental in the characterization of energy storage materials, with atomic resolution images providing the detailed structural features that are needed to understand their properties. Atomically…

Materials Science · Physics 2026-04-21 Ninon Scherz , Shashwat Anand , Colin Ophus , Tucker Holstun , Mary Scott , Tara P. Mishra , Gerbrand Ceder