English
Related papers

Related papers: Designing an exploratory phase 2b platform trial i…

200 papers

This paper proposes a novel approach for locally stable convergence to Nash equilibrium in duopoly noncooperative games based on a distributed event-triggered control scheme. The proposed approach employs extremum seeking, with sinusoidal…

Optimization and Control · Mathematics 2024-04-12 Victor Hugo Pereira Rodrigues , Tiago Roux Oliveira , Miroslav Krstić , Tamer Başar

Conventional approaches to statistical inference preclude structures that facilitate incorporation of supplemental information acquired from similar circumstances. For example, the analysis of data obtained using perfusion computed…

Applications · Statistics 2015-11-18 Thomas A. Murray , Brian P. Hobbs , Bradley P. Carlin

This paper proposes a mathematical approach for robust control of a nanoscale drug delivery system in treatment of atherosclerosis. First, a new nonlinear lumped model is introduced for mass transport in the arterial wall, and its accuracy…

Systems and Control · Electrical Eng. & Systems 2021-11-24 Alireza Rowhanimanesh , Mohammad-R Akbarzadeh-T

Bimetallic nanoparticles serve as a vital class of catalysts with tunable properties suitable for diverse catalytic reactions, yet a comprehensive understanding of their structural evolution under operational conditions as well as their…

Materials Science · Physics 2025-02-04 Yaxin Tang , Mingao Hou , Qian He , Guangfu Luo

In oncology, phase II or multiple expansion cohort trials are crucial for clinical development plans. This is because they aid in identifying potent agents with sufficient activity to continue development and confirm the proof of concept.…

Methodology · Statistics 2024-05-24 Takuya Yoshimoto , Satoru Shinoda , Kouji Yamamoto , Kouji Tahata

This paper aims at investigating the problem of fast convergence to the Nash equilibrium (NE) for N-Player noncooperative differential games. The proposed method is such that the players attain their NE point without steady-state…

Optimization and Control · Mathematics 2023-01-13 Zahra Zahedi , Alireza Khayatian , Mohammad Mehdi Arefi , Shen Yin

New generation in vitro high-throughput screening (HTS) assays for the assessment of engineered nanomaterials provide an opportunity to learn how these particles interact at the cellular level, particularly in relation to injury pathways.…

Applications · Statistics 2013-01-14 Trina Patel , Donatello Telesca , Saji George , André E. Nel

In order to find a measure of the dynamical features of phase separation kinetics during spinodal decomposition of a liquid binary mixture (like water and cyclohexane , water and 2,6 lutidiene or methanol and cyclohexane), we study both the…

Soft Condensed Matter · Physics 2016-04-21 Milan K. Hazra , Sarmistha Sarkar , Biman Bagchi

Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes,…

Here we study the shapes of droplets captured between chemically distinct parallel plates. This work is a preliminary step toward characterizing the influence of second-phase bridging between biomolecular surfaces on their solution…

Soft Condensed Matter · Physics 2021-08-19 L. R. Pratt , D. T. Gomez , A. Muralidharan , N. Pesika

In a real federated learning (FL) system, communication overhead for passing model parameters between the clients and the parameter server (PS) is often a bottleneck. Hierarchical federated learning (HFL) that poses multiple edge servers…

Machine Learning · Computer Science 2024-08-20 Xingrun Yan , Shiyuan Zuo , Rongfei Fan , Han Hu , Li Shen , Puning Zhao , Yong Luo

The nonadiabatic transition probabilities in the two-level systems are calculated analytically by using the monodromy matrix determining the global feature of the underlying differential equation. We study the time-dependent 2x2 Hamiltonian…

Quantum Physics · Physics 2009-11-10 T. Kato , K. Nakamura , M. Lakshmanan

The Smoothed Particle Hydrodynamics (SPH) is a particle-based, Lagrangian method for fluid-flow simulations. In this work, fundamental concepts of this method are first briefly recalled. Then, the ability to accurately model granular…

Geophysics · Physics 2016-02-26 Kamil Szewc

The constraint coordinate-momentum phase space (CPS) formulation of finite-state quantum systems has recently revealed that the triangle window function approach is an isomorphic representation of the exact population-population correlation…

Quantum Physics · Physics 2024-05-21 Xin He , Xiangsong Cheng , Baihua Wu , Jian Liu

We present preliminary results from recent high-resolution double-degenerate merger simulations with the Smooth Particle Hydrodynamics (SPH) technique. We put particular emphasis on verification and validation in our effort and show the…

Non-adiabatic molecular dynamics (NAMD) has become an essential computational technique for studying the photophysical relaxation of molecular systems after light absorption. These phenomena require approximations that go beyond the…

Federated Learning (FL) has emerged as a promising decentralized learning (DL) approach that enables the use of distributed data without compromising user privacy. However, FL poses several key challenges. First, it is frequently assumed…

Machine Learning · Computer Science 2025-09-29 Zahid Iqbal

Nonadiabatic transition dynamics lies at the core of many electron/hole transfer, photoactivated, and vacuum field-coupled processes. About a century after Ehrenfest proposed "Phasenraum" and the Ehrenfest theorem, we report a conceptually…

Quantum Physics · Physics 2024-04-09 Baihua Wu , Xin He , Jian Liu

Standard A/B tests in online experiments face statistical power challenges when testing multiple candidates simultaneously, while adaptive experimental designs (AED) alone fall short in inferring experiment statistics such as the average…

Machine Learning · Computer Science 2025-06-04 Qining Zhang , Tanner Fiez , Yi Liu , Wenyang Liu

Currently, practitioners follow a top-down approach in automotive development projects. However, recent studies have shown that this top-down approach is not suitable for the implementation and testing of modern automotive systems.…

Software Engineering · Computer Science 2021-07-13 Carsten Wiecher , Jannik Fischbach , Joel Greenyer , Andreas Vogelsang , Carsten Wolff , Roman Dumitrescu