Related papers: Designing an exploratory phase 2b platform trial i…
The Hubbard model, despite its simplicity, is remarkably successful at describing numerous many-body phenomena. However, due to the small class of problems which can be solved exactly, there has been substantial interest in quantum…
It is highly desirable to borrow information from external data to augment a control arm in a randomized clinical trial, especially in settings where the sample size for the control arm is limited. However, a main challenge in borrowing…
We study a nonlocal variant of a thermodynamically consistent phase field model for binary mixtures of micropolar fluids, i.e., fluids exhibiting internal rotations. The model is described by a Navier--Stokes--Cahn--Hilliard system that…
The US FDA's Project Optimus initiative that emphasizes dose optimization prior to marketing approval represents a pivotal shift in oncology drug development. It has a ripple effect for rethinking what changes may be made to conventional…
Nucleic acids such as mRNA have emerged as a promising therapeutic modality with the capability of addressing a wide range of diseases. Lipid nanoparticles (LNPs) as a delivery platform for nucleic acids were used in the COVID-19 vaccines…
We develop a non-cooperative game-theoretic model for the problem of graph minor-embedding to show that optimal compiling of adiabatic quantum programs in the sense of Nash equilibrium is possible.
This paper presents the first thermodynamic assessment of binary and pseudo-binary phase diagrams in the Ba--La--S and Ga--La--S systems by means of the CALPHAD method. Experimental phase diagram equilibrium data and thermodynamic…
We introduce a new phase field model for binary mixtures of incompressible micropolar fluids, which are among the simplest categories of fluids exhibiting internal rotations. The model fulfils local and global dissipation inequalities so…
We propose a two-level structural optimization method for obtaining an approximate optimal shape of piecewise developable surface without specifying internal boundaries between surface patches. The condition for developability of a…
Analysis of data from randomized controlled trials in vulnerable populations requires special attention when assessing treatment effect by a score measuring, e.g., disease stage or activity together with onset of prevalent terminal events.…
The Cahn-Hilliard system has been used to describe a wide number of phase separation processes, from co-polymer systems to lipid membranes. In this work the convergence properties of a closest-point based scheme is investigated. In place of…
We present a nonadiabatic classical-trajectory approach that offers the best of both worlds between fewest-switches surface hopping (FSSH) and quasiclassical mapping dynamics. This mapping approach to surface hopping (MASH) propagates the…
Theoretical models of a spin-polarized voltage probe (SPVP) tunnel-coupled to the helical edge states (HES) of a quantum spin Hall system (QSHS) are studied. Our first model of the SPVP comprises $N_{P}$ spin-polarized modes (subprobes),…
Objective: Natural language processing can help minimize human intervention in identifying patients meeting eligibility criteria for clinical trials, but there is still a long way to go to obtain a general and systematic approach that is…
Emerging technologies based on liquid crystal (LC) materials increasingly leverage the presence of nanoscale defects, unlike the canonical application of LCs -- LC displays. The inherent nanoscale characteristics of LC defects present both…
Surface nanobubbles (NBs) are stable gaseous phases in liquids that form at the interface with solid substrates. They have been particularly intriguing for their high stability that contradicts theoretical expectations and their potential…
We demonstrate a simple and scalable approach to increase conversion efficiencies of nonlinear metasurfaces by incorporating them into multipass cells and by letting the pump beam to interact with the metasurfaces multiple times. We…
Platform trials gained popularity during the last few years as they increase flexibility compared to multi-arm trials by allowing new experimental arms entering when the trial already started. Using a shared control group in platform trials…
In this publication we introduce SAMPLE, a structure search approach for commensurate organic monolayers on inorganic substrates. Such monolayers often show rich polymorphism with diverse molecular arrangements in differently shaped unit…
We investigate the spectral properties of the Su-Schrieffer-Heeger (SSH) model with sublattice-dependent onsite nonlinearity. Two complementary approaches are employed in our studies. First, Bloch state solutions under periodic boundary…