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Purpose: To develop a cardiac T1 mapping method for free-breathing 3D T1 mapping of the whole heart at 3T with transmit B1 (B1+) correction Methods: A free-breathing, ECG-gated inversion recovery sequence with spoiled gradient-echo readout…

Medical Physics · Physics 2021-11-16 Paul Kyu Han , Thibault Marin , Yanis Djebra , Vanessa Landes , Yue Zhuo , Georges El Fakhri , Chao Ma

An end-to-end image analysis pipeline is presented for the abdominal MRI protocol used in the UK Biobank on the first 38,971 participants. Emphasis is on the processing steps necessary to ensure a high-level of data quality and consistency…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Nicolas Basty , Yi Liu , Madeleine Cule , E. Louise Thomas , Jimmy D. Bell , Brandon Whitcher

Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Yundi Zhang , Chen Chen , Suprosanna Shit , Sophie Starck , Daniel Rueckert , Jiazhen Pan

PURPOSE: Magnetic Resonance Fingerprinting (MRF) with spiral readout enables rapid quantification of tissue relaxation times. However, it is prone to blurring due to off-resonance effects. Hence, fat blurring into adjacent regions might…

In real-time (RT) cardiac cine imaging, a stack of 2D slices is collected sequentially under free-breathing conditions. A complete heartbeat from each slice is then used for cardiac function quantification. The inter-slice respiratory…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Chong Chen , Yingmin Liu , Orlando P. Simonetti , Rizwan Ahmad

This study aimed to evaluate the potential of 3D echo-planar imaging (EPI) for improving the reliability of $T_2^*$-weighted ($T_2^*w$) data and quantification of $\textit{R}_2^*$ decay rate and susceptibility ($\chi$) compared to…

Medical Physics · Physics 2024-01-01 Yujia Huang , Lin Chen , Xu Li , Jiaen Liu

Objective: To develop an accurate myocardial T1 mapping technique at 5T using Look-Locker-based multiple inversion-recovery with the real-time spoiled gradient echo (GRE) acquisition. Approach: The proposed T1 mapping technique (mIR-rt)…

Medical Physics · Physics 2025-08-29 Linqi Ge , Yihang Zhang , Huibin Zhu , Lang Zhang , Yihang Zhou , Haifeng Wang , Dong Liang , Hairong Zheng , Yanjie Zhu

Purpose: To develop a 3D distortion-free reduced-FOV diffusion-prepared GRE sequence and demonstrate its in-vivo application for diffusion imaging of the spinal cord in healthy volunteers. Methods: A 3D multi-shot reduced-FOV…

Purpose: To develop and validate an acquisition and processing technique that enables fully self-gated 4D flow imaging with whole-heart coverage in a fixed five-minute scan. Theory and Methods: The data are acquired continuously using…

Image and Video Processing · Electrical Eng. & Systems 2020-11-26 Aaron Pruitt , Adam Rich , Yingmin Liu , Ning Jin , Lee Potter , Matthew Tong , Saurabh Rajpal , Orlando Simonetti , Rizwan Ahmad

Conventional cardiovascular magnetic resonance (CMR) cine imaging relies on binning multiple heartbeats into a single cardiac cycle, which fails in arrhythmic patients where beat-to-beat variability causes motion artifacts and loss of…

Purpose: To develop and evaluate a new pulse sequence for highly accelerated distortion-free diffusion MRI (dMRI) by inserting additional echoes without prolonging TR, when generalized slice dithered enhanced resolution (gSlider)…

Magnetic resonance fingerprinting (MRF) can successfully recover quantitative multi-parametric maps of human tissue in a very short acquisition time. Due to their pseudo-random nature, the large spatial undersampling artifacts can be…

Background: Conventional cardiovascular magnetic resonance (CMR) in paediatric and congenital heart disease uses 2D, breath-hold, balanced steady state free precession (bSSFP) cine imaging for assessment of function and cardiac-gated,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Mark Wrobel , Michele Pascale , Tina Yao , Ruaraidh Campbell , Elena Milano , Michael Quail , Jennifer Steeden , Vivek Muthurangu

Late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) can directly visualize nonviable myocardium with hyperenhanced intensities with respect to normal myocardium. For heart attack patients, it is crucial to facilitate the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-24 Dong Wei , Ying Sun , Sim-Heng Ong , Ping Chai , Lynette L Teo , Adrian F Low

Background: Cardiovascular MRI (CMR) faces challenges due to the interference of bright fat signals in visualizing anatomical structures. Effective fat suppression is crucial when using whole-heart CMR. Conventional methods often fall short…

Medical Physics · Physics 2023-11-14 Adèle L. C. Mackowiak , Davide Piccini , Jessica A. M. Bastiaansen

Purpose: Whole-heart MRA techniques typically target pre-determined motion states and address cardiac and respiratory dynamics independently. We propose a novel fast reconstruction algorithm, applicable to ungated free-running sequences,…

Purpose: To develop a fat-water separation approach that corrects bipolar readout gradient induced effects, without additional scans, that is compatible with any fat-water separation method. Theory and Methods: The proposed approach…

Medical Physics · Physics 2025-05-20 Jorge Campos Pazmino , Renée-Claude Bider , Véronique Fortier , Ives R. Levesque

The deposits of fat on the surroundings of the heart are correlated to several health risk factors such as atherosclerosis, carotid stiffness, coronary artery calcification, atrial fibrillation and many others. These deposits vary unrelated…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Érick Oliveira Rodrigues , FFC Morais , NAOS Morais , LS Conci , LV Neto , Aura Conci

In this work, we proposed a continuous-acquisition strategy using a gradient echo (GRE) inversion recovery sequence based on spiral trajectories to simultaneously obtain the $T_1$ mapping and CINE imaging. The acquisition is using a…

Image and Video Processing · Electrical Eng. & Systems 2022-05-18 Qing Zou , Mathews Jacob

The amount of fat on the surroundings of the heart is correlated to several health risk factors such as carotid stiffness, coronary artery calcification, atrial fibrillation, atherosclerosis, cancer incidence and others. Furthermore, the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 É. O. Rodrigues , A. Conci , F. F. C. Morais , M. G. Pérez