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When exposed to a thermal gradient, reaction networks can convert thermal energy into the chemical selection of states that would be unfavourable at equilibrium. The kinetics of reaction paths, and thus how fast they dissipate available…

Statistical Mechanics · Physics 2021-09-01 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

Because of its nonequilibrium character, active matter in a steady state can drive engines that autonomously deliver work against a constant mechanical force or torque. As a generic model for such an engine, we consider systems that contain…

Statistical Mechanics · Physics 2019-11-15 Patrick Pietzonka , Étienne Fodor , Christoph Lohrmann , Michael E. Cates , Udo Seifert

Using the fluctuation theorem supplemented with geometric arguments, we derive universal features of the (long-time) efficiency fluctuations for thermal and isothermal machines operating under steady or periodic driving, close or far from…

Statistical Mechanics · Physics 2014-11-26 Gatien Verley , Tim Willaert , Christian Van den Broeck , Massimiliano Esposito

Brownian particles interacting sequentially with distinct temperatures and driving forces at each stroke have been tackled as a reliable alternative for the construction of engine setups. However they can behave very inefficiently depending…

Statistical Mechanics · Physics 2022-12-28 Iago N. Mamede , Angel L. L. Stable , C. E. Fiore

From the steam engine to current nano-devices, the design of efficient thermal machines has been instrumental in modern societies. In its essence a thermal engine can be thought as a working substance, in contact with two or more baths,…

Statistical Mechanics · Physics 2016-03-18 Michele Campisi , Rosario Fazio

Cells sense and predict their environment via energy-dissipating pathways. However, it is unclear whether dissipation helps or harms prediction. Here we study dissipation and prediction for a minimal sensory module of receptors that…

Molecular Networks · Quantitative Biology 2013-12-20 Nils B. Becker , Andrew Mugler , Pieter Rein ten Wolde

Many biological functions are executed by molecular machines, which consume energy and convert it into mechanical work. Biological machines have evolved to transport cargo, facilitate folding of proteins and RNA, remodel chromatin and…

Biological Physics · Physics 2020-04-15 Mauro L. Mugnai , Changbong Hyeon , Michael Hinczewski , D. Thirumalai

Dissipative structures are open dynamical systems that sustain coherent macroscopic organization by continuously exchanging energy and matter with their environment and generating entropy. A recent thermodynamic analysis of the paradigmatic…

Chaotic Dynamics · Physics 2026-05-15 Álvaro G. López , Inés P. Mariño , Alfonso Delgado-Bonal

Predicting structural and energetic properties of a molecular system is one of the fundamental tasks in molecular simulations, and it has use cases in chemistry, biology, and medicine. In the past decade, the advent of machine learning…

Chemical Physics · Physics 2022-08-23 Sajjad Heydari , Stefano Raniolo , Lorenzo Livi , Vittorio Limongelli

This work presents a performance analysis for diffusive molecular communication with mobile transmit and receive nanomachines. To begin with, the optimal test is obtained for symbol detection at the receiver nanomachine. Subsequently,…

Information Theory · Computer Science 2017-10-04 Neeraj Varshney , Aditya K. Jagannatham , Pramod K. Varshney

We demonstrate and characterize a first-principles approach to modeling the mass action dynamics of metabolism. Starting from a basic definition of entropy expressed as a multinomial probability density using Boltzmann probabilities with…

Chemical Physics · Physics 2024-07-10 William R. Cannon , Samuel Britton , Mikahl Banwarth-Kuhn , Mark Alber

As biochemical systems may frequently suffer from limited energy resources so that internal molecular fluctuation has to be utilized to induce random rhythm, it is still a great theoretical challenge to understand the elementary principles…

Chemical Physics · Physics 2021-01-04 Zhiyu Cao , Huijun Jiang , Zhonghuai Hou

We derive the general relations between the maximum power, maximum efficiency and minimum dissipation for the irreversible heat engine in nonlinear response regime. In this context, we use the minimally nonlinear irreversible model and…

Statistical Mechanics · Physics 2018-01-31 I. Iyyappan , M. Ponmurugan

We consider a general class of nonlinear diffusive models with bulk dissipation and boundary driving, and derive its hydrodynamic description in the large size limit. Both the average macroscopic behavior and the fluctuating properties of…

Statistical Mechanics · Physics 2013-10-29 A. Prados , A. Lasanta , Pablo I. Hurtado

We study quantum transport through two-terminal nanoscale devices in contact with two particle reservoirs at different temperatures and chemical potentials. We discuss the general expressions controlling the electric charge current, heat…

Mesoscale and Nanoscale Physics · Physics 2017-08-04 G. Bevilacqua , G. Grosso , G. Menichetti , G. Pastori Parravicini

Heat dissipation is ubiquitous in living systems, which constantly convert distinct forms of energy into each other. The transport of thermal energy in liquids and even within proteins is well understood but kinetic energy transfer across a…

Soft Condensed Matter · Physics 2026-01-07 Brandon Neff , Matthias Heyden

Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce broken detailed balance at the molecular scale. This molecular scale breaking of detailed balance is crucial to achieve biological functions such as…

Biological Physics · Physics 2018-05-02 F. Gnesotto , F. Mura , J. Gladrow , C. P. Broedersz

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

Biological Physics · Physics 2008-03-07 Debashish Chowdhury

This letter exposes a tight connection between the thermodynamic efficiency of information processing and predictive inference. A generalized lower bound on dissipation is derived for partially observable information engines which are…

Statistical Mechanics · Physics 2020-02-12 Susanne Still

Analytical formulas for effective drift, diffusivity, run times, and run lengths are derived for an intracellular transport system consisting of a cargo attached to two cooperative but not identical molecular motors (for example, kinesin-1…

Subcellular Processes · Quantitative Biology 2021-01-22 Joseph J. Klobusicky , John Fricks , Peter R. Kramer