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We consider the classical problems of estimating the mean of an $n$-dimensional normally (with identity covariance matrix) or Poisson distributed vector under the squared loss. In a Bayesian setting the optimal estimator is given by the…

Statistics Theory · Mathematics 2021-09-13 Yury Polyanskiy , Yihong Wu

When dealing with Bayesian inference the choice of the prior often remains a debatable question. Empirical Bayes methods offer a data-driven solution to this problem by estimating the prior itself from an ensemble of data. In the…

Methodology · Statistics 2020-05-13 Ilja Klebanov , Alexander Sikorski , Christof Schütte , Susanna Röblitz

In applications of Bayesian procedures, once a class of priors has been chosen, it may be tempting to fix the prior's hyperparameters from the data, in an empirical Bayes (EB) fashion, usually by their maximum marginal likelihood estimates…

Statistics Theory · Mathematics 2026-04-14 Stefano Rizzelli , Judith Rousseau , Sonia Petrone

Most bandit algorithm designs are purely theoretical. Therefore, they have strong regret guarantees, but also are often too conservative in practice. In this work, we pioneer the idea of algorithm design by minimizing the empirical Bayes…

Machine Learning · Computer Science 2020-06-12 Chih-Wei Hsu , Branislav Kveton , Ofer Meshi , Martin Mladenov , Csaba Szepesvari

In this paper, we consider the problem of parametric empirical Bayes estimation of an i.i.d. prior in high-dimensional Bayesian linear regression, with random design. We obtain the asymptotic distribution of the variational Empirical Bayes…

Statistics Theory · Mathematics 2026-02-25 Seunghyun Lee , Nabarun Deb

Empirical Bayes (EB) is a popular framework for large-scale inference that aims to find data-driven estimators to compete with the Bayesian oracle that knows the true prior. Two principled approaches to EB estimation have emerged over the…

Statistics Theory · Mathematics 2024-11-21 Yandi Shen , Yihong Wu

Bayesian optimization usually assumes that a Bayesian prior is given. However, the strong theoretical guarantees in Bayesian optimization are often regrettably compromised in practice because of unknown parameters in the prior. In this…

Machine Learning · Computer Science 2018-11-26 Zi Wang , Beomjoon Kim , Leslie Pack Kaelbling

Identifying leading measurement units from a large collection is a common inference task in various domains of large-scale inference. Testing approaches, which measure evidence against a null hypothesis rather than effect magnitude, tend to…

Methodology · Statistics 2020-11-17 Nicholas C. Henderson , Michael A. Newton

The Robbins estimator is the most iconic and widely used procedure in the empirical Bayes literature for the Poisson model. On one hand, this method has been recently shown to be minimax optimal in terms of the regret (excess risk over the…

Statistics Theory · Mathematics 2025-09-16 Soham Jana , Yury Polyanskiy , Yihong Wu

We consider the problem of empirical Bayes estimation for (multivariate) Poisson means. Existing solutions that have been shown theoretically optimal for minimizing the regret (excess risk over the Bayesian oracle that knows the prior) have…

Statistics Theory · Mathematics 2023-07-06 Soham Jana , Yury Polyanskiy , Anzo Teh , Yihong Wu

Multivariate, heteroscedastic errors complicate statistical inference in many large-scale denoising problems. Empirical Bayes is attractive in such settings, but standard parametric approaches rest on assumptions about the form of the prior…

Statistics Theory · Mathematics 2024-01-02 Jake A. Soloff , Adityanand Guntuboyina , Bodhisattva Sen

Large-scale randomized experiments, sometimes called A/B tests, are increasingly prevalent in many industries. Though such experiments are often analyzed via frequentist $t$-tests, arguably such analyses are deficient: $p$-values are hard…

Methodology · Statistics 2020-03-27 F. Richard Guo , James McQueen , Thomas S. Richardson

One of the main goals of mathematical modeling in systems medicine related to medical applications is to obtain patient-specific parameterizations and model predictions. In clinical practice, however, the number of available measurements…

Methodology · Statistics 2017-06-22 Ilja Klebanov , Alexander Sikorski , Christof Schütte , Susanna Röblitz

We study the problem of preferential Bayesian optimization (BO), where we aim to optimize a black-box function with only preference feedback over a pair of candidate solutions. Inspired by the likelihood ratio idea, we construct a…

Machine Learning · Computer Science 2024-05-30 Wenjie Xu , Wenbin Wang , Yuning Jiang , Bratislav Svetozarevic , Colin N. Jones

We consider the fixed-budget best arm identification problem with rewards following normal distributions. In this problem, the forecaster is given $K$ arms (or treatments) and $T$ time steps. The forecaster attempts to find the arm with the…

Machine Learning · Statistics 2024-04-16 Junpei Komiyama

We study empirical Bayes estimation of the effect sizes of $N$ units from $K$ noisy observations on each unit. We show that it is possible to achieve near-Bayes optimal mean squared error, without any assumptions or knowledge about the…

Methodology · Statistics 2021-08-11 Nikolaos Ignatiadis , Sujayam Saha , Dennis L. Sun , Omkar Muralidharan

We develop an empirical Bayes framework for experimental design that leverages information from prior related studies. When a researcher has access to estimates from previous studies on similar parameters, they can use empirical Bayes to…

Econometrics · Economics 2026-02-25 Zhiheng You

We study best-arm identification (BAI) in the fixed-budget setting. Adaptive allocations based on upper confidence bounds (UCBs), such as UCBE, are known to work well in BAI. However, it is well-known that its optimal regret is…

Machine Learning · Computer Science 2024-10-24 Rong J. B. Zhu , Yanqi Qiu

Adding domain knowledge to a learning system is known to improve results. In multi-parameter Bayesian frameworks, such knowledge is incorporated as a prior. On the other hand, various model parameters can have different learning rates in…

Machine Learning · Computer Science 2022-06-22 Sareh Nabi , Houssam Nassif , Joseph Hong , Hamed Mamani , Guido Imbens

We study the Gaussian sequence compound decision problem and analyze a Bayesian nonparametric estimator from an empirical Bayes, regret-based perspective. Motivated by sharp results for the classical nonparametric maximum likelihood…

Statistics Theory · Mathematics 2026-02-24 Nikolaos Ignatiadis , Sid Kankanala
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