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Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between…
Here we propose and implement a generalized mathematical model to find the time evolution of population in infectious diseases and apply the model to study the recent COVID-19 pandemic. Our model at the core is a non-local generalization of…
In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…
Crowd models can be used for the simulation of people movement in the built environment. Crowd model outputs have been used for evaluating safety and comfort of pedestrians, inform crowd management and perform forensic investigations.…
Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late…
Mathematical modeling of epidemic spreading has been widely adopted to estimate the threats of epidemic diseases (i.e., the COVID-19 pandemic) as well as to evaluate epidemic control interventions. The indoor place is considered to be a…
Epidemiology models play a key role in understanding and responding to the COVID-19 pandemic. In order to build those models, scientists need to understand contributing factors and their relative importance. A large strand of literature has…
Airborne pathogen transmission mechanisms play a key role in the spread of infectious diseases such as COVID-19. In this work, we propose a computational fluid dynamics (CFD) approach to model and statistically characterize airborne…
The emergence and spread of deadly pandemics has repeatedly occurred throughout history, causing widespread infections and loss of life. The rapid spread of pandemics have made governments across the world adopt a range of actions,…
Partial differential equation (PDE) models for infectious diseases, while less common than their ordinary differential equation (ODE) counterparts, have found successful applications for many years. Such models are typically of…
A deterministic pathogen transmission model based on high-fidelity physics has been developed. The model combines computational fluid dynamics and computational crowd dynamics in order to be able to provide accurate tracing of viral matter…
The Covid-19 pandemic has taken millions of lives, demonstrating the tragedy and disruption of respiratory diseases, and how difficult they can be to manage. However, there is still significant debate in the scientific community as to which…
Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…
We propose a multi-scale lung model to investigate spatio-temporal distributions of ventilation variables. Lung envelope and large airway geometries are derived from CT scans; smaller airways are generated using a physiologically consistent…
High-resolution large-eddy simulation (LES) is exploited to study indoor air turbulence and its effect on the dispersion of respiratory virus-laden aerosols and subsequent transmission risks. The methodology is applied to assess two…
During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…
Over the past two decades there has been a number of global outbreaks of viral diseases. This has accelerated the efforts to model and forecast the disease spreading, in order to find ways to confine the spreading regionally and between…
The global public health landscape is perpetually challenged by the looming threat of infectious diseases. Central to addressing this concern is the imperative to prevent and manage disease transmission during pandemics, particularly in…
Motivated by analogies between the spreading of human-to-human infections and of chemical processes, we develop a comprehensive model that accounts both for infection and for transport. In this analogy, the three different populations of…
Among the realistic ingredients to be considered in the computational modeling of infectious diseases, human mobility represents a crucial challenge both on the theoretical side and in view of the limited availability of empirical data. In…