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Radiomics-based machine learning models show promise for clinical decision support but are vulnerable to distribution shifts caused by variations in imaging protocols, positioning, and segmentation. This study systematically investigates…

Machine Learning · Computer Science 2025-10-30 Sarmad Ahmad Khan , Simon Bernatz , Zahra Moslehi , Florian Buettner

Recent advancements in signal processing and machine learning coupled with developments of electronic medical record keeping in hospitals and the availability of extensive set of medical images through internal/external communication…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Parnian Afshar , Arash Mohammadi , Konstantinos N. Plataniotis , Anastasia Oikonomou , Habib Benali

The importance of radiomics features for predicting patient outcome is now well-established. Early study of prognostic features can lead to a more efficient treatment personalisation. For this reason new radiomics features obtained through…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Paul Desbordes , Diksha , Benoit Macq

Image features need to be robust against differences in positioning, acquisition and segmentation to ensure reproducibility. Radiomic models that only include robust features can be used to analyse new images, whereas models with non-robust…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Alex Zwanenburg , Stefan Leger , Linda Agolli , Karoline Pilz , Esther G. C. Troost , Christian Richter , Steffen Löck

Radiomics is a nascent field in quantitative imaging that uses advanced algorithms and considerable computing power to describe tumor phenotypes, monitor treatment response, and assess normal tissue toxicity quantifiably. Remarkable…

Medical Physics · Physics 2019-11-26 Jiwoong Jeong , Arif Ali , Tian Liu , Hui Mao , Walter J. Curran , Xiaofeng Yang

We develop and validate a novel spherical radiomics framework for predicting key molecular biomarkers using multiparametric MRI. Conventional Cartesian radiomics extract tumor features on orthogonal grids, which do not fully capture the…

Medical Physics · Physics 2025-10-22 Haotian Feng , Ke Sheng

Federated learning and its application to medical image segmentation have recently become a popular research topic. This training paradigm suffers from statistical heterogeneity between participating institutions' local datasets, incurring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-19 Matthis Manthe , Stefan Duffner , Carole Lartizien

Background: The reproducibility of machine-learning models in prostate cancer detection across different MRI vendors remains a significant challenge. Methods: This study investigates Support Vector Machines (SVM) and Random Forest (RF)…

Objective: Radiomics, an emerging tool for medical image analysis, is potential towards precisely characterizing gastric cancer (GC). Whether using one-slice 2D annotation or whole-volume 3D annotation remains a long-time debate, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Lingwei Meng , Di Dong , Xin Chen , Mengjie Fang , Rongpin Wang , Jing Li , Zaiyi Liu , Jie Tian

In patients with biochemical recurrence of prostate cancer and negative PSMA PET/CT, radiomics features extracted from recurrence-prone organs can predict clinical progression and progression-free survival. In a cohort of 132 patients,…

Medical image retrieval is a valuable field for supporting clinical decision-making, yet current methods primarily support 2D images and require fully annotated queries, limiting clinical flexibility. To address this, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Inye Na , Nejung Rue , Jiwon Chung , Hyunjin Park

Multiparametric radiological imaging is vital for detection, characterization and diagnosis of many different diseases. The use of radiomics for quantitative extraction of textural features from radiological imaging is increasing moving…

Computer Vision and Pattern Recognition · Computer Science 2020-02-07 Vishwa S. Parekh , Michael A. Jacobs

Background. Radiomic features, derived from a region of interest (ROI) in medical images, are valuable as prognostic factors. Selecting an appropriate ROI is critical, and many recent studies have focused on leveraging multiple ROIs by…

Radiomics features extract quantitative information from medical images, towards the derivation of biomarkers for clinical tasks, such as diagnosis, prognosis, or treatment response assessment. Different image discretization parameters…

As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past a few years. Recent studies in radiomics aim to investigate the relationship between tumors imaging features and…

Quantitative Methods · Quantitative Biology 2019-07-11 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

Purpose: To develop a radiomics filtering technique for characterizing spatial-encoded regional pulmonary ventilation information on lung CT. Methods: The lung volume was segmented on 46 CT images, and a 3D sliding window kernel was…

Medical Physics · Physics 2023-01-11 Zhenyu Yang , Kyle J Lafata , Xinru Chen , James Bowsher , Yushi Chang , Chunhao Wang , Fang-Fang Yin

Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

This work is devoted to the stability/resolution analysis of several imaging functionals in complex environments. We consider both linear functionals in the wavefield as well as quadratic functionals based on wavefield correlations. Using…

Analysis of PDEs · Mathematics 2015-01-27 G. Bal , O. Pinaud , L. Ryzhik

Different technical and physical factors may affect the image quality reconstructed using a Computed Tomography system. We have developed and designed a 2D Gamma Computed Tomography set up to study the effect of some physical parameters.…

Instrumentation and Detectors · Physics 2022-08-19 Kajal Kumari , Mayank Goswami

Computer aided diagnosis (CAD) of Breast Cancer (BRCA) images has been an active area of research in recent years. The main goals of this research is to develop reliable automatic methods for detecting and diagnosing different types of BRCA…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Marco A. V. M. Grinet , Nuno M. Garcia , Ana I. R. Gouveia , Jose A. F. Moutinho , Abel J. P. Gomes