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Fulfilling the promise of precision medicine requires accurately and precisely classifying disease states. For cancer, this includes prediction of survival time from a surfeit of covariates. Such data presents an opportunity for improved…

Applications · Statistics 2017-06-22 Shannon R. McCurdy , Annette Molinaro , Lior Pachter

Carbon taxes are increasingly popular among policymakers but remain politically contentious. A key challenge relates to their distributional impacts; the extent to which tax burdens differ across population groups. As a response, a growing…

General Economics · Economics 2026-01-13 Jules Linden , Cathal O'Donoghue , Denisa Sologon

We present a simple model of adaptive radiations in evolution based on species competition. Competition is found to promote species divergence and branching, and to dampen the net species production. In the model simulations, high taxonomic…

Populations and Evolution · Quantitative Biology 2007-05-23 Birgitte Freiesleben De Blasio , Fabio Vittorio De Blasio

In high-dimensional survival analysis, effective variable selection is crucial for both model interpretation and predictive performance. This paper investigates Cox regression with lasso and adaptive lasso penalties in genomic datasets…

Methodology · Statistics 2025-07-02 Pilar González-Barquero , Rosa E. Lillo , Álvaro Méndez-Civieta

Here we introduce a general class of multiple calibration birth-death tree priors for use in Bayesian phylogenetic inference. All tree priors in this class separate ancestral node heights into a set of "calibrated nodes" and "uncalibrated…

Populations and Evolution · Quantitative Biology 2013-11-21 Joseph Heled , Alexei J. Drummond

Causal inference on time series data is a challenging problem, especially in the presence of unobserved confounders. This work focuses on estimating the causal effect between two time series that are confounded by a third, unobserved time…

Machine Learning · Statistics 2024-11-19 Felix Schur , Jonas Peters

Estimation of molecular evolutionary divergence times requires models of rate change. These vary with regard to the assumption of what quantity is penalized. The possibilities considered are the rate of evolution, the log of the rate of…

Genomics · Quantitative Biology 2007-12-31 Peter J Waddell

The problem of how to best select variables for confounding adjustment forms one of the key challenges in the evaluation of exposure effects in observational studies, and has been the subject of vigorous recent activity in causal inference.…

Methodology · Statistics 2021-12-02 Kelly Van Lancker , Oliver Dukes , Stijn Vansteelandt

Survival analysis concerns the task of predicting the time until an event occurs. Often used in the medical field, survival analysis deals with incomplete (i.e., censored) data, for instance, from patients who did not experience the event…

Machine Learning · Computer Science 2026-05-29 Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

Theoretical ecologists have long sought to understand how the persistence of populations depends on biotic and abiotic factors. Classical work showed that demographic stochasticity causes the mean time to extinction to increase…

Populations and Evolution · Quantitative Biology 2014-08-06 Otso Ovaskainen , Baruch Meerson

Genetic information and environmental factors determine the path of an individuals life and therefore, the evolution of its entire species. We have succeeded in proposing and studying a model that captures this idea. In our model, a…

Populations and Evolution · Quantitative Biology 2021-07-28 N. Abadi , G. Abramson

The anisotropy of wood within the radial-tangential (RT) growth plane has a major influence on the cracking behavior perpendicular to grain. Within the scope of this work, a two-dimensional discrete element model is developed, consisting of…

Materials Science · Physics 2007-05-23 Falk K. Wittel , Gerhard Dill-Langer , Bernd-H. Kroeplin

Wood deformation, in particular when subject to compression, exhibits scale-free avalanche-like behavior as well as structure-dependent localization of deformation. We have taken three-dimensional (3D) x-ray tomographs during compression…

Statistical Mechanics · Physics 2022-11-10 Tero Mäkinen , Alisa Halonen , Juha Koivisto , Mikko J. Alava

Tree-based methods are popular nonparametric tools in studying time-to-event outcomes. In this article, we introduce a novel framework for survival trees and ensembles, where the trees partition the dynamic survivor population and can…

Methodology · Statistics 2020-01-14 Yifei Sun , Sy Han Chiou , Mei-Cheng Wang

We use food webs generated by a model to investigate the effects of deleting species on other species in the web and on the web as a whole. The model incorporates a realistic population dynamics, adaptive foragers and other features which…

Populations and Evolution · Quantitative Biology 2007-05-23 Christopher Quince , Paul Higgs , Alan McKane

In this article we build a mathematical model for forest growth and we compare this model with a computer forest simulator named SORTIE. The main ingredient taken into account in both models is the competition for light between trees. The…

Populations and Evolution · Quantitative Biology 2016-09-02 Pierre Magal , Zhengyang Zhang

Understanding the future climate is crucial for informed policy decisions on climate change prevention and mitigation. Earth system models play an important role in predicting future climate, requiring accurate representation of complex…

Machine Learning · Computer Science 2024-01-09 Christian Reimers , David Hafezi Rachti , Guahua Liu , Alexander J. Winkler

Destabilization of the water cycle threatens human lives and livelihoods. Meanwhile our understanding of whether and how changes in vegetation cover could trigger abrupt transitions in moisture regimes remains incomplete. This challenge…

Tumor shape is a key factor that affects tumor growth and metastasis. This paper proposes a topological feature computed by persistent homology to characterize tumor progression from digital pathology and radiology images and examines its…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Chul Moon , Qiwei Li , Guanghua Xiao

The paper introduces a PDE model for the growth of a tree stem or a vine. The equations describe the elongation due to cell growth, and the response to gravity and to external obstacles. An additional term accounts for the tendency of a…

Optimization and Control · Mathematics 2020-11-10 Alberto Bressan , Michele Palladino , Wen Shen
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