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The stochastic simulation of biological systems is an increasingly popular technique in bioinformatics. It often is an enlightening technique, which may however result in being computational expensive. We discuss the main opportunities to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Marco Aldinucci , Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Massimo Torquati , Angelo Troina

Single neuron models have a long tradition in computational neuroscience. Detailed biophysical models such as the Hodgkin-Huxley model as well as simplified neuron models such as the class of integrate-and-fire models relate the input…

Neurons and Cognition · Quantitative Biology 2016-11-02 Simone Carlo Surace , Jean-Pascal Pfister

An efficient, generalizable physical simulator with universal uncertainty estimates has wide applications in robot state estimation, planning, and control. In this paper, we build such a simulator for two scenarios, planar pushing and ball…

We present a 2-dimensional cellular automaton model for the simulation of pedestrian dynamics. The model is extremely efficient and allows simulations of large crowds faster than real time since it includes only nearest-neighbour…

Statistical Mechanics · Physics 2007-05-23 Andreas Schadschneider

Combined Transmission and Distribution Systems (CoTDS) simulation for power systems requires development of algorithms and software that are numerically stable and at the same time accurately simulate dynamic events that can occur in…

Systems and Control · Computer Science 2018-01-08 Ramakrishnan Venkatraman , Siddhartha Kumar Khaitan , Venkataramana Ajjarapu

The training process of neural networks is known to be time-consuming, and having a deep architecture only aggravates the issue. This process consists mostly of matrix operations, among which matrix multiplication is the bottleneck. Several…

Machine Learning · Computer Science 2025-06-17 Sana Ebrahimi , Rishi Advani , Abolfazl Asudeh

Molecular dynamics (MD) simulations are a central tool in science and engineering enabling the study of dynamical behavior and the link between microscopic structure and macroscopic function. Their high computational cost, however, has…

Chemical Physics · Physics 2026-01-22 Salman N. Salman , Sergey A. Shteingolts , Ron Levie , Dan Mendels

Learning robot tasks or controllers using deep reinforcement learning has been proven effective in simulations. Learning in simulation has several advantages. For example, one can fully control the simulated environment, including halting…

Machine Learning · Computer Science 2018-09-18 Jeroen van Baar , Alan Sullivan , Radu Cordorel , Devesh Jha , Diego Romeres , Daniel Nikovski

The advantage of Cellular Potts Model (CPM) is due to its ability for introducing cell-cell interaction based on the well known statistical model i.e. the Potts model. On the other hand, Lattice gas Cellular Automata (LGCA) can simulate…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Mehrdad Ghaemi , Amene Shahrokhi

Center-based models are used to simulate the mechanical behavior of biological cells during embryonic development or cancer growth. To allow for the simulation of biological populations potentially growing from a few individual cells to…

Numerical Analysis · Mathematics 2022-07-27 Per Lötstedt , Sonja Mathias

This paper studies an input-driven one-state differential equation model initially developed for an experimentally demonstrated dynamic molecular switch that switches like synapses in the brain do. The linear-in-the-state and…

Machine Learning · Computer Science 2025-08-22 H. I. Nurdin , C. A. Nijhuis

Neural networks have been able to achieve groundbreaking accuracy at tasks conventionally considered only doable by humans. Using stochastic gradient descent, optimization in many dimensions is made possible, albeit at a relatively high…

Machine Learning · Computer Science 2017-07-17 Hirsh R. Agarwal , Andrew Huang

Cancer is a complex disease that is characterized by uncontrolled growth and division of cells. It involves a complex interplay between genetic and environmental factors that lead to the initiation and progression of tumors. Recent advances…

Biomolecules · Quantitative Biology 2025-02-07 Reza Bozorgpour

In this paper we study the concept of using the interaction between waves and a trainable medium in order to construct a matrix-vector multiplier. In particular we study such a device in the context of the backpropagation algorithm, which…

Neural and Evolutionary Computing · Computer Science 2015-10-14 Michiel Hermans , Thomas Van Vaerenbergh

Significant progress in computer hardware and software have enabled molecular dynamics (MD) simulations to model complex biological phenomena such as protein folding. However, enabling MD simulations to access biologically relevant…

Biomolecules · Quantitative Biology 2019-08-02 Heng Ma , Debsindhu Bhowmik , Hyungro Lee , Matteo Turilli , Michael T. Young , Shantenu Jha , Arvind Ramanathan

Even though Deep Reinforcement Learning (DRL) showed outstanding results in the fields of Robotics and Games, it is still challenging to implement it in the optimization of industrial processes like wastewater treatment. One of the…

Recent developments in Machine Learning approaches for modelling physical systems have begun to mirror the past development of numerical methods in the computational sciences. In this survey, we begin by providing an example of this with…

Machine Learning · Computer Science 2023-04-04 Artur P. Toshev , Ludger Paehler , Andrea Panizza , Nikolaus A. Adams

The advent of high-power Hall thrusters and the increasing interest towards their use as a primary propulsion system for various missions have given a new boost to the efforts aiming at self-consistent predictive modeling of this thruster…

Plasma Physics · Physics 2022-06-10 Farbod Faraji , Maryam Reza , Aaron Knoll

Navigating topological transitions in cellular mechanical systems is a significant challenge for existing simulation methods. While abstract models lack predictive capabilities at the cellular level, explicit network representations…

Graphics · Computer Science 2024-04-30 Logan Numerow , Yue Li , Stelian Coros , Bernhard Thomaszewski

Reversible bipolar nano-switches that can be set and read electronically in a solid-state two-terminal device are very promising for applications. We have performed molecular-dynamics simulations that mimic systems with oxygen vacancies…

Mesoscale and Nanoscale Physics · Physics 2015-05-20 S. E. Savel'ev , A. S. Alexandrov , A. M. Bratkovsky , R. Stanley Williams