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Current efforts in the biomedical sciences and related interdisciplinary fields are focused on gaining a molecular understanding of health and disease, which is a problem of daunting complexity that spans many orders of magnitude in…

Quantitative Methods · Quantitative Biology 2014-01-24 Julián Candia , Jayanth R. Banavar , Wolfgang Losert

Mass spectrometry-based proteomics has become the tool of choice for identifying and quantifying the proteome of an organism. Though recent years have seen a tremendous improvement in instrument performance and the computational tools used,…

Over the past decade, the revolution in single-cell sequencing has enabled the simultaneous molecular profiling of various modalities across thousands of individual cells, allowing scientists to investigate the diverse functions of complex…

Computation and Language · Computer Science 2024-12-05 Junhao Liu , Siwei Xu , Lei Zhang , Jing Zhang

The great majority of current voice technology applications relies on acoustic features characterizing the vocal tract response, such as the widely used MFCC of LPC parameters. Nonetheless, the airflow passing through the vocal folds, and…

Sound · Computer Science 2020-01-01 Thomas Drugman , Paavo Alku , Abeer Alwan , Bayya Yegnanarayana

Experiments in research on memory, language, and in other areas of cognitive science are increasingly being analyzed using Bayesian methods. This has been facilitated by the development of probabilistic programming languages such as Stan,…

Methodology · Statistics 2020-03-02 Daniel J. Schad , Michael Betancourt , Shravan Vasishth

Non-invasive estimation of respiratory physiology using computational algorithms promises to be a valuable technique for future clinicians to detect detrimental changes in patient pathophysiology. However, few clinical algorithms used to…

Quantitative Methods · Quantitative Biology 2021-09-22 Gregory Rehm , Jimmy Nguyen , Chelsea Gilbeau , Marc T Bomactao , Chen-Nee Chuah , Jason Adams

Traditional data science education often omits training on research workflows: the process that moves a scientific investigation from raw data to coherent research question to insightful contribution. In this paper, we elaborate basic…

Computers and Society · Computer Science 2021-06-09 Sara Stoudt , Valeri N. Vasquez , Ciera C. Martinez

The spatial information of sound plays a crucial role in various situations, ranging from daily activities to advanced engineering technologies. To fully utilize its potential, numerous research studies on spatial audio signal processing…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-14 Natsuki Ueno , Shoichi Koyama

Machine Learning (ML) has already fundamentally changed several businesses. More recently, it has also been profoundly impacting the computational science and engineering domains, like geoscience, climate science, and health science. In…

The development and approval of new treatments generates large volumes of results, such as summaries of efficacy and safety. However, it is commonly overlooked that analyzing clinical study data also produces data in the form of results.…

Computers and Society · Computer Science 2022-04-22 Joana M Barros , Lukas A Widmer , Mark Baillie , Simon Wandel

As the world population gets older, the healthcare system must be adapted, among others by providing continuous health monitoring at home and in the city. The social activities have a significant role in everyone health status. Hence, this…

Computers and Society · Computer Science 2016-12-01 Loïc Sevrin , Bertrand Massot , Norbert Noury , Nacer Abouchi , Fabrice Jumel , Jacques Saraydaryan

Clinical coding is crucial for healthcare billing and data analysis. Manual clinical coding is labour-intensive and error-prone, which has motivated research towards full automation of the process. However, our analysis, based on US English…

Computation and Language · Computer Science 2025-06-19 Yidong Gan , Maciej Rybinski , Ben Hachey , Jonathan K. Kummerfeld

Live-cell imaging (LCI) technology enables the detailed spatio-temporal characterization of living cells at the single-cell level, which is critical for advancing research in the life sciences, from biomedical applications to bioprocessing.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Johannes Seiffarth , Keitaro Kasahara , Michelle Bund , Benita Lückel , Richard D. Paul , Matthias Pesch , Lennart Witting , Michael Bott , Dietrich Kohlheyer , Katharina Nöh

High-throughput metabolomics investigations, when conducted in large human cohorts, represent a potentially powerful tool for elucidating the biochemical diversity and mechanisms underlying human health and disease. Large-scale metabolomics…

This report characterized the suitability of existing datasets for devising new Machine Learning models, decision making methods, and analysis algorithms to improve Collaborative Problem Solving and then enumerated requirements for future…

Machine Learning · Computer Science 2024-12-25 Gnaneswar Villuri , Alex Doboli

Computing practice today depends on visual output to drive almost all user interaction. Other senses, such as audition, may be totally neglected, or used tangentially, or used in highly restricted specialized ways. We have excellent audio…

Sound · Computer Science 2015-06-25 Michael J. O'Donnell , Ilia Bisnovatyi

Development and homeostasis in multicellular systems both require exquisite control over spatial molecular pattern formation and maintenance. Advances in spatially-resolved and high-throughput molecular imaging methods such as multiplexed…

Quantitative Methods · Quantitative Biology 2023-03-30 Alex J. Lee , Robert Cahill , Reza Abbasi-Asl

Advances in single-cell omics allow for unprecedented insights into the transcription profiles of individual cells. When combined with large-scale perturbation screens, through which specific biological mechanisms can be targeted, these…

Machine Learning · Computer Science 2023-10-24 Alejandro Tejada-Lapuerta , Paul Bertin , Stefan Bauer , Hananeh Aliee , Yoshua Bengio , Fabian J. Theis

Collaborative competitions have gained popularity in the scientific and technological fields. These competitions involve defining tasks, selecting evaluation scores, and devising result verification methods. In the standard scenario,…

Machine Learning · Computer Science 2024-08-22 Sergio Nava-Muñoz , Mario Graff , Hugo Jair Escalante