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Related papers: The current state of single-cell proteomics data a…

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In the field of computational science and engineering, workflows often entail the application of various software, for instance, for simulation or pre- and postprocessing. Typically, these components have to be combined in arbitrarily…

Software Engineering · Computer Science 2022-11-15 Philipp Diercks , Dennis Gläser , Ontje Lünsdorf , Michael Selzer , Bernd Flemisch , Jörg F. Unger

In modeling time series data, we often need to augment the existing data records to increase the modeling accuracy. In this work, we describe a number of techniques to extract dynamic information about the current state of a large…

Machine Learning · Computer Science 2022-05-20 Jeeyung Kim , Mengtian Jin , Youkow Homma , Alex Sim , Wilko Kroeger , Kesheng Wu

Objective: This study addresses conceptual issues around data standardisation in audiology, and outlines steps toward achieving it. It reports a survey of the computational audiology community on their current understanding, needs, and…

Research increasingly relies on computational methods to analyze experimental data and predict molecular properties. Current approaches often require researchers to use a variety of tools for statistical analysis and machine learning,…

Quantitative Methods · Quantitative Biology 2025-12-01 Luke Rimmo Lego , Samantha Gauthier , Denver Jn. Baptiste

In the recent years, singing voice separation systems showed increased performance due to the use of supervised training. The design of training datasets is known as a crucial factor in the performance of such systems. We investigate on how…

Sound · Computer Science 2019-06-07 Laure Prétet , Romain Hennequin , Jimena Royo-Letelier , Andrea Vaglio

Powerful detectors at modern experimental facilities routinely collect data at multiple GB/s. Online analysis methods are needed to enable the collection of only interesting subsets of such massive data streams, such as by explicitly…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-23 Rafael Vescovi , Ryan Chard , Nickolaus Saint , Ben Blaiszik , Jim Pruyne , Tekin Bicer , Alex Lavens , Zhengchun Liu , Michael E. Papka , Suresh Narayanan , Nicholas Schwarz , Kyle Chard , Ian Foster

Many pressing medical challenges - such as diagnosing disease, enhancing directed stem cell differentiation, and classifying cancers - have long been hindered by limitations in our ability to quantify proteins in single cells.…

Genomics · Quantitative Biology 2018-08-06 Harrison Specht , Nikolai Slavov

Feature selection techniques are essential for high-dimensional data analysis. In the last two decades, their popularity has been fuelled by the increasing availability of high-throughput biomolecular data where high-dimensionality is a…

Quantitative Methods · Quantitative Biology 2024-01-18 Pengyi Yang , Hao Huang , Chunlei Liu

The transformers have achieved significant accomplishments in the natural language processing as its outstanding parallel processing capabilities and highly flexible attention mechanism. In addition, increasing studies based on transformers…

Computation and Language · Computer Science 2024-07-19 Wei Lan , Guohang He , Mingyang Liu , Qingfeng Chen , Junyue Cao , Wei Peng

[Background] Nowadays, there is a massive growth of data volume and speed in many types of systems. It introduces new needs for infrastructure and applications that have to handle streams of data with low latency and high throughput.…

Software Engineering · Computer Science 2019-09-25 Alexandre Vianna , Waldemar Ferreira , Kiev Gama

Large systems biology projects can encompass several workgroups often located in different countries. An overview about existing data standards in systems biology and the management, storage, exchange and integration of the generated data…

Databases · Computer Science 2009-12-15 Gerhard Mayer

As single-cell gene expression data analysis continues to grow, the need for reliable clustering methods has become increasingly important. The prevalence of heuristic means for method choice could lead to inaccurate reports if…

Quantitative Methods · Quantitative Biology 2026-05-19 Owen Visser , Somnath Datta

Artificial intelligence is increasingly being integrated into professional audio production workflows, yet a gap persists between the tools developers produce and the requirements of practising sound designers. This paper investigates this…

Sound · Computer Science 2026-05-27 Nelly Garcia , Joshua Reiss

Over the last two decades, scientific workflow management systems (SWfMS) have emerged as a means to facilitate the design, execution, and monitoring of reusable scientific data processing pipelines. At the same time, the amounts of data…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-03-29 Marc Bux , Ulf Leser

Single-cell data integration can provide a comprehensive molecular view of cells, and many algorithms have been developed to remove unwanted technical or biological variations and integrate heterogeneous single-cell datasets. Despite their…

Quantitative Methods · Quantitative Biology 2024-03-04 Rong Ma , Eric D. Sun , David Donoho , James Zou

Current computational-emotion research has focused on applying acoustic properties to analyze how emotions are perceived mathematically or used in natural language processing machine learning models. While recent interest has focused on…

Sound · Computer Science 2021-07-06 Daniel Szelogowski

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

Mass spectrometry based clinical proteomics has emerged as a powerful tool for highthroughput protein profiling and biomarker discovery. Recent improvements in mass spectrometry technology have boosted the potential of proteomic studies in…

Methodology · Statistics 2016-02-10 Alexia Kakourou , Werner Vach , Simone Nicolardi , Yuri van der Burgt , Bart Mertens

Single-particle traces of the diffusive motion of molecules, cells, or animals are by-now routinely measured, similar to stochastic records of stock prices or weather data. Deciphering the stochastic mechanism behind the recorded dynamics…

Statistical Mechanics · Physics 2023-09-14 Henrik Seckler , Janusz Szwabinski , Ralf Metzler

Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrumentation and resulting data, sophisticated…