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Diabetic retinopathy is a leading cause of blindness in diabetic patients and early detection plays a crucial role in preventing vision loss. Traditional diagnostic methods are often time-consuming and prone to errors. The emergence of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Saif Ur Rehman Khan , Muhammad Nabeel Asim , Sebastian Vollmer , Andreas Dengel

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmenting the…

Diabetic Retinopathy (DR) is an art and science of recording and classifying the retinal images of a diabetic patient. DR classification deals with classifying retinal fundus image into five stages on the basis of severity of diabetes. One…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Nishi Doshi , Urvi Oza , Pankaj Kumar

Artificial intelligence (AI) classification holds promise as a novel and affordable screening tool for clinical management of ocular diseases. Rural and underserved areas, which suffer from lack of access to experienced ophthalmologists may…

Quantitative Methods · Quantitative Biology 2019-06-19 Minhaj Alam , David Le , Jennifer I. Lim , R. V. P. Chan , Xincheng Yao

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

OCTA is a crucial non-invasive imaging technique for diagnosing and monitoring retinal diseases like diabetic retinopathy, age-related macular degeneration, and glaucoma. Current 2D-based methods for retinal vessel (RV) segmentation offer…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Chuang Liu , Nan Guo

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

Optical Coherence Tomography Angiography (OCTA) is a promising tool for detecting Alzheimer's disease (AD) by imaging the retinal microvasculature. Ophthalmologists commonly use region-based analysis, such as the ETDRS grid, to study OCTA…

Image and Video Processing · Electrical Eng. & Systems 2023-11-13 Shouyue Liu , Jinkui Hao , Yanwu Xu , Huazhu Fu , Xinyu Guo , Jiang Liu , Yalin Zheng , Yonghuai Liu , Jiong Zhang , Yitian Zhao

Deep Ensemble Convolutional Neural Networks has become a methodology of choice for analyzing medical images with a diagnostic performance comparable to a physician, including the diagnosis of Diabetic Retinopathy. However, commonly used…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Pratinav Seth , Adil Khan , Ananya Gupta , Saurabh Kumar Mishra , Akshat Bhandari

Diabetic Retinopathy (DR) is a serious microvascular complication of diabetes, and one of the leading causes of vision loss worldwide. Although automated detection and grading, with Deep Learning (DL), can reduce the burden on…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Shramana Dey , Zahir Khan , T. A. PramodKumar , B. Uma Shankar , Ashis K. Dhara , Ramachandran Rajalakshmi , Rajiv Raman , Sushmita Mitra

Diabetic Retinopathy (DR) is among the worlds leading vision loss causes in diabetic patients. DR is a microvascular disease that affects the eye retina, which causes vessel blockage and therefore cuts the main source of nutrition for the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Israa Odeh , Mouhammd Alkasassbeh , Mohammad Alauthman

Automatic classification of Diabetic Retinopathy (DR) can assist ophthalmologists in devising personalized treatment plans, making it a critical component of clinical practice. However, imbalanced data distribution in the dataset becomes a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Abdul Hannan , Zahid Mahmood , Rizwan Qureshi , Hazrat Ali

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality for the visualisation of microvasculature in vivo that has encountered broad adoption in retinal research. OCTA potential in the assessment of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Ylenia Giarratano , Eleonora Bianchi , Calum Gray , Andrew Morris , Tom MacGillivray , Baljean Dhillon , Miguel O. Bernabeu

Optical coherence tomography angiography (OCTA) is a novel imaging modality that has been widely utilized in ophthalmology and neuroscience studies to observe retinal vessels and microvascular systems. However, publicly available OCTA…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Mingchao Li , Kun Huang , Qiuzhuo Xu , Jiadong Yang , Yuhan Zhang , Zexuan Ji , Keren Xie , Songtao Yuan , Qinghuai Liu , Qiang Chen

To explore the clinical validity of elastic deformation of optical coherence tomography (OCT) images for data augmentation in the development of deep-learning model for detection of diabetic macular edema (DME).

Image and Video Processing · Electrical Eng. & Systems 2021-07-14 Daniel Bar-David , Laura Bar-David , Yinon Shapira , Rina Leibu , Dalia Dori , Ronit Schneor , Anath Fischer , Shiri Soudry

Diabetic Retinopathy (DR) is an ocular condition caused by a sustained high level of sugar in the blood, which causes the retinal capillaries to block and bleed, causing retinal tissue damage. It usually results in blindness. Early…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Md. Simul Hasan Talukder , Ajay Kirshno Sarkar , Sharmin Akter , Md. Nuhi-Alamin

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Botond Fazekas , Guilherme Aresta , Dmitrii Lachinov , Sophie Riedl , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Purpose: This study explores the feasibility of using generative machine learning (ML) to translate Optical Coherence Tomography (OCT) images into Optical Coherence Tomography Angiography (OCTA) images, potentially bypassing the need for…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Rashadul Hasan Badhon , Atalie Carina Thompson , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam

Retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) are promising tools for the (early) diagnosis of Alzheimer's disease (AD). These non-invasive imaging techniques are cost-effective and more…

Image and Video Processing · Electrical Eng. & Systems 2022-09-09 Yasemin Turkan , F. Boray Tek