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This paper introduces FedGenGMM, a novel one-shot federated learning approach for Gaussian Mixture Models (GMM) tailored for unsupervised learning scenarios. In federated learning (FL), where multiple decentralized clients collaboratively…

Machine Learning · Computer Science 2025-06-03 Sophia Zhang Pettersson , Kuo-Yun Liang , Juan Carlos Andresen

Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown. Human complex diseases are likely influenced by…

Methodology · Statistics 2014-05-27 Zihuai He , Min Zhang , Xiaowei Zhan , Qing Lu

Personalized medication aims to tailor healthcare to individual patient characteristics. However, the heterogeneity of patient data across healthcare systems presents significant challenges to achieving accurate and effective personalized…

Artificial Intelligence · Computer Science 2024-12-10 Jiechao Gao , Yuangang Li

Large language models (LLMs) increasingly adopt Mixture-of-Experts (MoE) architectures to scale model capacity while reducing computation. Fine-tuning these MoE-based LLMs often requires access to distributed and privacy-sensitive data,…

Machine Learning · Computer Science 2026-03-24 Zihan Fang , Qianru Wang , Haonan An , Zheng Lin , Yiqin Deng , Xianhao Chen , Yuguang Fang

As edge devices become increasingly powerful, data analytics are gradually moving from a centralized to a decentralized regime where edge compute resources are exploited to process more of the data locally. This regime of analytics is…

Applications · Statistics 2023-07-04 Xubo Yue , Raed Al Kontar , Ana María Estrada Gómez

Federated learning is a distributed paradigm that allows multiple parties to collaboratively train deep models without exchanging the raw data. However, the data distribution among clients is naturally non-i.i.d., which leads to severe…

Machine Learning · Computer Science 2023-01-31 Tianfei Zhou , Ender Konukoglu

Federated learning (FL) is a collaborative machine learning approach that enables multiple clients to train models without sharing their private data. With the rise of deep learning, large-scale models have garnered significant attention…

Machine Learning · Computer Science 2025-09-09 Ziwei Zhan , Wenkuan Zhao , Yuanqing Li , Weijie Liu , Xiaoxi Zhang , Chee Wei Tan , Chuan Wu , Deke Guo , Xu Chen

Federated Learning (FL) offers a decentralized approach to model training, where data remains local and only model parameters are shared between the clients and the central server. Traditional methods, such as Federated Averaging (FedAvg),…

Machine Learning · Computer Science 2025-02-12 Jiahao Lai , Jiaqi Li , Jian Xu , Yanru Wu , Boshi Tang , Siqi Chen , Yongfeng Huang , Wenbo Ding , Yang Li

Federated Learning (FL) is a privacy-preserving machine learning framework facilitating collaborative training across distributed clients. However, its performance is often compromised by data heterogeneity among participants, which can…

Machine Learning · Computer Science 2026-02-16 Ziru Niu , Hai Dong , A. K. Qin

Federated learning, where algorithms are trained across multiple decentralized devices without sharing local data, is increasingly popular in distributed machine learning practice. Typically, a graph structure $G$ exists behind local…

Machine Learning · Statistics 2022-09-20 Huiyuan Wang , Xuyang Zhao , Wei Lin

The increasing requirements for data protection and privacy has attracted a huge research interest on distributed artificial intelligence and specifically on federated learning, an emerging machine learning approach that allows the…

Machine Learning · Computer Science 2024-02-16 Jose L. Salmeron , Irina Arévalo , Antonio Ruiz-Celma

While large pre-trained models have achieved impressive performance across AI tasks, their deployment in privacy-sensitive and distributed environments remains challenging. Federated learning (FL) offers a viable solution by enabling…

Machine Learning · Computer Science 2025-08-26 Ruofan Jia , Weiying Xie , Jie Lei , Jitao Ma , Haonan Qin , Leyuan Fang

Federated Multi-Task Learning (FMTL) enables multiple clients performing heterogeneous tasks without exchanging their local data, offering broad potential for privacy preserving multi-task collaboration. However, most existing methods focus…

Machine Learning · Computer Science 2025-06-02 Yipan Wei , Yuchen Zou , Yapeng Li , Bo Du

Federated or multi-site studies have distinct advantages over single-site studies, including increased generalizability, the ability to study underrepresented populations, and the opportunity to study rare exposures and outcomes. However,…

Machine Learning · Statistics 2023-09-25 Larry Han , Zhu Shen , Jose Zubizarreta

Chemistry research has both high material and computational costs to conduct experiments. Institutions thus consider chemical data to be valuable and there have been few efforts to construct large public datasets for machine learning.…

Machine Learning · Computer Science 2022-05-10 Wei Zhu , Jiebo Luo , Andrew White

Federated Learning (FL) has emerged as a significant paradigm for training machine learning models. This is due to its data-privacy-preserving property and its efficient exploitation of distributed computational resources. This is achieved…

Machine Learning · Computer Science 2025-01-22 Mustafa Ghaleb , Mohanad Obeed , Muhamad Felemban , Anas Chaaban , Halim Yanikomeroglu

High-dimensional phenotypes hold promise for richer findings in association studies, but testing of several phenotype traits aggravates the grand challenge of association studies, that of multiple testing. Several methods have recently been…

Methodology · Statistics 2013-05-14 Pekka Marttinen , Jussi Gillberg , Aki Havulinna , Jukka Corander , Samuel Kaski

There is an extensive literature on methods for meta-analysis of diagnostic studies, but it mainly focuses on a single test. However, the better understanding of a particular disease has led to the development of multiple tests. A…

Methodology · Statistics 2020-10-19 Aristidis K. Nikoloulopoulos

Federated learning (FL) enables multiple clients with distributed data sources to collaboratively train a shared model without compromising data privacy. However, existing FL paradigms face challenges due to heterogeneity in client data…

Machine Learning · Computer Science 2024-10-21 Brianna Mueller , W. Nick Street , Stephen Baek , Qihang Lin , Jingyi Yang , Yankun Huang

Federated Learning (FL) facilitates collaborative model training across decentralized clients while preserving data privacy by avoiding raw data exchange. Despite its potential, FL performance is often compromised by data heterogeneity…

Machine Learning · Computer Science 2026-05-12 Qijun Hou , Yuchen Shi , Pingyi Fan , Khaled B. Letaief
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