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Since the breakout of coronavirus disease (COVID-19), the computer-aided diagnosis has become a necessity to prevent the spread of the virus. Detecting COVID-19 at an early stage is essential to reduce the mortality risk of the patients. In…

We propose a novel automatic method for accurate segmentation of the prostate in T2-weighted magnetic resonance imaging (MRI). Our method is based on convolutional neural networks (CNNs). Because of the large variability in the shape, size,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-01 Davood Karimi , Golnoosh Samei , Yanan Shao , Septimiu Salcudean

Timely and rapid diagnoses are core to informing on optimum interventions that curb the spread of COVID-19. The use of medical images such as chest X-rays and CTs has been advocated to supplement the Reverse-Transcription Polymerase Chain…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Ogechukwu Ukwandu , Hanan Hindy , Elochukwu Ukwandu

This paper investigates the application of deep learning models for lung Computed Tomography (CT) image analysis. Traditional deep learning frameworks encounter compatibility issues due to variations in slice numbers and resolutions in CT…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Chih-Chung Hsu , Chih-Yu Jian , Chia-Ming Lee , Chi-Han Tsai , Sheng-Chieh Dai

Understanding the viral dynamics and immunizing antibodies of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for devising better therapeutic and prevention strategies for COVID-19. Here, we present a Bayesian…

Applications · Statistics 2023-07-27 Tracy Q. Dong , Elizabeth R. Brown

The clinical spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the strain of coronavirus that caused the COVID-19 pandemic, is broad, extending from asymptomatic infection to severe immunopulmonary reactions that, if…

Quantitative Methods · Quantitative Biology 2022-07-18 Aaron Wang , Feng Li , Samantha Chiang , Jennifer Fulcher , Otto Yang , David Wong , Fang Wei

The recent zoonotic coronavirus virus outbreak of a novel type [COVID 19] has necessitated the adequate understanding of the evolutionary pathway of zoonotic viruses which adversely affects human populations for therapeutic constructs to…

Other Quantitative Biology · Quantitative Biology 2020-05-07 Adejoke Olukayode Obajuluwa , Pius Abimbola Okiki , Tiwalola Madoc Obajuluwa , Olakunle Bamikole Afolabi

Since the onset of the COVID-19 pandemic in 2020, millions of people have succumbed to this deadly virus. Many attempts have been made to devise an automated method of testing that could detect the virus. Various researchers around the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Samyak Prajapati , Japman Singh Monga , Shaanya Singh , Amrit Raj , Yuvraj Singh Champawat , Chandra Prakash

One of the most serious global health threat is COVID-19 pandemic. The emphasis on improving diagnosis and increasing the diagnostic capability helps stopping its spread significantly. Therefore, to assist the radiologist or other medical…

Image and Video Processing · Electrical Eng. & Systems 2020-12-07 Khalfalla Awedat , Almabrok Essa

Due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) being a novel virus, there are currently no known effective antiviral drugs capable of slowing its progress. To accelerate the discovery of potential drug candidates,…

Biomolecules · Quantitative Biology 2020-09-29 Lokesh Agrawal , Thanasis Poullikkas , Scott Eisenhower , Carlo Monsanto , Ranjith Kumar Bakku

COVID-19 is a highly contagious respiratory infection that has affected a large population across the world and continues with its devastating consequences. It is imperative to detect COVID-19 at the earliest to limit the span of infection.…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Saddam Hussain Khan , Anabia Sohail , Asifullah Khan

Since the first case of COVID-19 disease in Wuhan in December 2019, there is a worldwide struggle to reduce the transmission of acute respiratory syndrome coronavirus SARS-CoV-2. Many countries worldwide decided to impose local lockdowns in…

Other Quantitative Biology · Quantitative Biology 2022-08-09 Daniela Dobrynin , Iryna Polishchuk , Boaz Pokroy

Deep learning models for COVID-19 detection from chest CT scans generally perform well when the training and test data originate from the same institution, but they often struggle when scans are drawn from multiple centres with differing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Asmita Yuki Pritha , Jason Xu , Daniel Ding , Justin Li , Aryana Hou , Xin Wang , Shu Hu

Automatic heart sound abnormality detection can play a vital role in the early diagnosis of heart diseases, particularly in low-resource settings. The state-of-the-art algorithms for this task utilize a set of Finite Impulse Response (FIR)…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Ahmed Imtiaz Humayun , Shabnam Ghaffarzadegan , Zhe Feng , Taufiq Hasan

COVID-19 was a significant challenge that led to the loss of numerous lives daily. Not only a certain country was involved in this outbreak, but even the world has suffered because of the coronavirus. Imaging techniques using computed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Sarmad Khan , Arslan Shaukat , Umer Asgher , Basim Azam

The COVID-19 pandemic has profoundly impacted global economies and healthcare systems, revealing critical vulnerabilities in both. In response, our study introduces a groundbreaking method for the detection of SARS-CoV-2 cDNA, leveraging…

We report a fast-track computationally-driven discovery of new SARS-CoV2 Main Protease (M$^{pro}$) inhibitors whose potency range from mM for initial non-covalent ligands to sub-$\mu$M for the final covalent compound (IC50=830 +/- 50 nM).…

An accurate seizure prediction system enables early warnings before seizure onset of epileptic patients. It is extremely important for drug-refractory patients. Conventional seizure prediction works usually rely on features extracted from…

Signal Processing · Electrical Eng. & Systems 2021-08-18 Yankun Xu , Jie Yang , Shiqi Zhao , Hemmings Wu , Mohamad Sawan

Lacunes of presumed vascular origin (lacunes) are associated with an increased risk of stroke, gait impairment, and dementia and are a primary imaging feature of the small vessel disease. Quantification of lacunes may be of great importance…

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