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Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Microscopy imaging plays a vital role in understanding many biological processes in development and disease. The recent advances in automation of microscopes and development of methods and markers for live cell imaging has led to rapid…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Saad Ullah Akram , Juho Kannala , Lauri Eklund , Janne Heikkilä

The analysis of dynamic organelles remains a formidable challenge, though key to understanding biological processes. We introduce Nellie, an automated and unbiased user-friendly pipeline for segmentation, tracking, and feature extraction of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Austin E. Y. T. Lefebvre , Gabriel Sturm , Ting-Yu Lin , Emily Stoops , Magdalena Preciado Lopez , Benjamin Kaufmann-Malaga , Kayley Hake

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

Current biological and medical research is aimed at obtaining a detailed spatiotemporal map of a live cell's interior to describe and predict cell's physiological state. We present here an algorithm for complete 3-D modelling of cellular…

Quantitative Methods · Quantitative Biology 2017-04-03 Renata Rychtarikova , Tomas Nahlik , Kevin Shi , Daria Malakhova , Petr Machacek , Rebecca Smaha , Jan Urban , Dalibor Stys

This paper introduces a software architecture for real-time object detection using machine learning (ML) in an augmented reality (AR) environment. Our approach uses the recent state-of-the-art YOLOv8 network that runs onboard on the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-07 Mikołaj Łysakowski , Kamil Żywanowski , Adam Banaszczyk , Michał R. Nowicki , Piotr Skrzypczyński , Sławomir K. Tadeja

ASCRIBE-XR, a novel computational platform designed to facilitate the visualization and exploration of 3D volumetric data and mesh data in the context of synchrotron experiments, is described. Using Godot and PC-VR technologies, the…

Human-Computer Interaction · Computer Science 2025-07-08 Ronald J. Pandolfi , Jeffrey J. Donatelli , Julian Todd , Daniela Ushizima

Within the past decade, the rise of applications based on artificial intelligence (AI) in general and machine learning (ML) in specific has led to many significant contributions within different domains. The applications range from robotics…

Computer Vision and Pattern Recognition · Computer Science 2021-03-09 Christoph Sager , Patrick Zschech , Niklas Kühl

3D modeling is becoming a well-developed field of medicine, but its applicability can be limited due to the lack of software allowing for easy utilizations of generated 3D visualizations. By leveraging recent advances in virtual reality, we…

Human-Computer Interaction · Computer Science 2020-12-07 Alex J. Deakyne , Erik N. Gaasedelen , Tinen L. Iles , Paul A. Iaizzo

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

Cancer detection and classification from gigapixel whole slide images of stained tissue specimens has recently experienced enormous progress in computational histopathology. The limitation of available pixel-wise annotated scans shifted the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Mehdi Naouar , Gabriel Kalweit , Ignacio Mastroleo , Philipp Poxleitner , Marc Metzger , Joschka Boedecker , Maria Kalweit

360 video captures the complete surrounding scenes with the ultra-large field of view of 360X180. This makes 360 scene understanding tasks, eg, segmentation and tracking, crucial for appications, such as autonomous driving, robotics. With…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Weiming Zhang , Dingwen Xiao , Aobotao Dai , Yexin Liu , Tianbo Pan , Shiqi Wen , Lei Chen , Lin Wang

PiNNAcLe is an implementation of our adaptive learn-on-the-fly algorithm for running machine-learning potential (MLP)-based molecular dynamics (MD) simulations -- an emerging approach to simulate the large-scale and long-time dynamics of…

Statistical Mechanics · Physics 2024-09-16 Yunqi Shao , Chao Zhang

Freehand 3D ultrasound enables volumetric imaging by tracking a conventional ultrasound probe during freehand scanning, offering enriched spatial information that improves clinical diagnosis. However, the quality of reconstructed volumes is…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Sheng Song , Yiting Chen , Duo Xu , Songhan Ge , Yunqian Huang , Junni Shi , Man Chen , Hongbo Chen , Rui Zheng

In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…

Machine Learning · Computer Science 2020-10-12 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Manuel González-Hidalgo

In-context learning (ICL) offers a promising paradigm for universal medical image analysis, enabling models to perform diverse image processing tasks without retraining. However, current ICL models for medical imaging remain limited in two…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Jiesi Hu , Jianfeng Cao , Yanwu Yang , Chenfei Ye , Yixuan Zhang , Hanyang Peng , Ting Ma

Vision Language Models (VLMs) have demonstrated remarkable performance in open-world zero-shot visual recognition. However, their potential in space-related applications remains largely unexplored. In the space domain, accurate manual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Samet Hicsonmez , Jose Sosa , Dan Pineau , Inder Pal Singh , Arunkumar Rathinam , Abd El Rahman Shabayek , Djamila Aouada

We present a highly scalable Monte Carlo (MC) three-dimensional photon transport simulation platform designed for heterogeneous computing systems. Through the development of a massively parallel MC algorithm using the Open Computing…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-06 Leiming Yu , Fanny Nina-Paravecino , David Kaeli , Qianqian Fang

Tracking many cells in time-lapse 3D image sequences is an important challenging task of bioimage informatics. Motivated by a study of brain-wide 4D imaging of neural activity in C. elegans, we present a new method of multi-cell tracking.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Osamu Hirose , Shotaro Kawaguchi , Terumasa Tokunaga , Yu Toyoshima , Takayuki Teramoto , Sayuri Kuge , Takeshi Ishihara , Yuichi Iino , Ryo Yoshida

Annolid is a deep learning-based software package designed for the segmentation, labeling, and tracking of research targets within video files, focusing primarily on animal behavior analysis. Based on state-of-the-art instance segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Chen Yang , Thomas A. Cleland